A5034011474- Photodynamic Therapy Research Studies
- Head and Neck Cancer Studies
- Oral Health Pathology and Treatment
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Thyroid Cancer Diagnosis and Treatment
- Advanced Biosensing Techniques and Applications
- Head and Neck Anomalies
- Thyroid and Parathyroid Surgery
- Reconstructive Surgery and Microvascular Techniques
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Tracheal and airway disorders
- Proteoglycans and glycosaminoglycans research
- Global Public Health Policies and Epidemiology
- Health disparities and outcomes
- Global Health Care Issues
- Lung Cancer Research Studies
- Renal cell carcinoma treatment
- Ear and Head Tumors
- Insurance, Mortality, Demography, Risk Management
- Cancer Immunotherapy and Biomarkers
- Experimental Behavioral Economics Studies
- HIV/AIDS oral health manifestations
Pontificia Universidad Católica de Chile
2008-2024
Universidad Loyola Andalucía
2022
Memorial Sloan Kettering Cancer Center
2012-2021
Clínica Las Condes
2018-2020
Instituto Tecnológico de Costa Rica
2017
Instituto de Agroquímica y Tecnología de Alimentos
2016
Consejo Superior de Investigaciones Científicas
2016
Instituto Nacional de Salud Pública
2016
Kettering University
2012
ABSTRACT Background An objective definition of clinically relevant extracapsular nodal spread (ECS) in head and neck squamous cell carcinoma (SCC) is unavailable. Methods Pathologic review 245 pathologically positive oral cavity SCC dissection specimens was performed. The presence/absence ECS, its extent (in millimeters), multiple primary tumor risk factors were related to disease‐specific survival (DSS) at a follow‐up 73 months. Results ECS detected 109 patients (44%). DSS significantly...
Early diagnosis and treatment of melanoma are essential to minimizing morbidity mortality. The presence lymph node metastases is a vital prognostic predictor, accurate identification by imaging has important implications for disease staging, prognosis, clinical outcome. Sentinel (SLN) mapping procedures limited lack intraoperative visualization tools that can aid determination spread delineate nodes from adjacent critical neural vascular structures. Newer methods circumventing these issues...
Resection of the primary tumor with negative margins is gold standard treatment for squamous cell carcinoma oral tongue (SCCOT). A microscopically positive surgical margin clearly associated a higher risk local recurrence, whereas has traditionally been defined as greater than 5.0 mm clearance from tumor, lesser arbitrarily designated close. The precise cutoff at which recurrence close approximates that remains unclear.To determine whether (<5.0 mm) would portend high after resection...
This study sought to develop prognostic tools that will accurately predict overall and cancer-related mortality risk of recurrence in individual patients with oral cancer based on host tumor characteristics. These would take into account numerous prognosticators beyond those covered by the traditional TNM (tumor-node-metastasis) staging system.Demographic, host, characteristics 1617 cavity, who were treated primarily surgery at a single-institution tertiary care center between 1985 2009,...
Sentinel lymph node (SLN) mapping agents approved for current surgical practice lack sufficient brightness and target specificity high-contrast, sensitive nodal visualization.To evaluate whether an ultrasmall, molecularly targeted core-shell silica nanoparticle (Cornell prime dots) can safely reliably identify optically avid SLNs in head neck melanoma during fluorescence-guided biopsy.This nonrandomized clinical trial enrolled patients aged 18 years or older with histologically confirmed...
The purpose of this study was to describe and compare how postoperative complications after oral cavity squamous cell carcinoma (SCC) surgery are reported in medical records, institutional billing claims, national clinical registries.The records 355 previously untreated patients who underwent for SCC at our institution were retrospectively reviewed complications. Information compared with claims National Surgical Quality Improvement Program (NSQIP) data.We identified 219 (62%) experiencing...
Objective.To analyze mortality and incidence for 28 cancers by deprivation status, age sex from 1990 to 2013.Materials methods.The data methodological approaches provided the Global Burden of Disease (GBD 2013) were used.Results.Trends 2013 show important changes in cancer epidemiology Mexico.While some a decreasing trend (lung, cervical) others emerge as relevant health priorities (prostate, breast, stomach, colorectal liver cancer).Age standardized rates all are higher northern states...
Spectrally distinct ultrasmall fluorescence silica particles as multiplexing tools address cancer heterogeneity and aid surgery.
Abstract Background Whether elective lymph neck dissection (ELND) is associated with improved survival in oral squamous cell carcinomas (SCC) of the maxillary alveolus/hard palate not known. Methods One hundred ninety‐nine patients presenting de novo and receiving treatment for clinically node negative SCC at 2 cancer centers between 1985 2011 were analyzed. Results Forty‐two (21%) received ELND. Occult nodal metastases present 29% dissected necks. The ELND group had more T3 to T4 status...
The AJCC/UICC staging system is a major tool in oncology, currently used worldwide for clinical, pathological and recurrent disease staging. Squamous cell carcinomas (SCC) of the head neck are heterogeneous disease. TNM classification offers reliable method estimating prognosis patients with cancer based on certain characteristics tumor. It also planning treatment, has helped to standardize way staged treatment results reported around world. Although original was solely anatomic extent...
Molecular testing contributes to improving the diagnosis of indeterminate thyroid nodules (ITNs). ThyroidPrint® is a ten-gene classifier aimed rule out malignancy in ITN. Post-validation studies are necessary determine real-world clinical benefit patients with A single-center, prospective, noninterventional utility study was performed, analyzing impact physicians' decisions for Demographics, nodule characteristics, benign call rates (BCRs), and surgical outcomes were measured....
Head and neck squamous cell carcinoma (HNSCC) is well known as a serious health problem worldwide, especially in low-income countries or those with limited resources, such most Latin America. International guidelines cannot always be applied to population from large region specific conditions. This study established American guideline for care of patients head cancer presented evidence HNSCC management considering availability oncologic benefit. A panel composed 41 experts systematically...
<h3>Objective</h3>To describe smoking and alcohol consumption trends in patients with oral cavity cancer over the past 25 years.<h3>Design</h3>Retrospective cohort study.<h3>Setting</h3>Single-institution tertiary care center.<h3>Patients</h3>Patients treated primarily surgery from 1985 to 2009. Patients previous head neck were excluded.<h3>Main Outcome Measures</h3>The medical records of 1617 reviewed. Patient demographics details on recorded. divided 5 different cohorts according year...
Postoperative complications after head and neck surgery carry the potential for significant morbidity. Estimating risk of in an individual patient is challenging.
We investigated reflectance confocal microscopy (RCM) as a possible noninvasive approach for the diagnosis of cancer and real-time assessment surgical margins.
Objective: After initial treatment, up to 30% of patients with papillary thyroid cancer (PTC) have incomplete response, mainly cervical lymph node (LN) disease. Previous studies suggested that active surveillance (AS) is a possible option for these patients. Our aim was report the results AS in PTC and LN Materials methods: In this retrospective observational study, we included adult treated followed PTC, who presented disease [...]