- Vestibular and auditory disorders
- Fungal Infections and Studies
- Acute Ischemic Stroke Management
- Autoimmune and Inflammatory Disorders Research
- Glaucoma and retinal disorders
- Atrial Fibrillation Management and Outcomes
- Ophthalmology and Eye Disorders
- Multiple Sclerosis Research Studies
- Cardiovascular Syncope and Autonomic Disorders
- Coronary Interventions and Diagnostics
- Cerebral Venous Sinus Thrombosis
Charles University
2021-2024
University Hospital in Motol
2021-2024
Background The possibility to better predict the severity of disease in a patient newly diagnosed with multiple sclerosis would allow treatment strategy be personalized and lead clinical outcomes. Prognostic biomarkers are highly needed. Objective To assess prognostic value intrathecal IgM synthesis, cerebrospinal fluid serum IL-2, IL-6, IL-10, chitinase 3-like 2 neurofilament heavy chains obtained early after onset disease. Methods 58 patients first manifestation were included. After...
Deterioration of dynamic visual acuity (DVA) as a result impaired vestibulo-ocular reflex (VOR) has been well described in peripheral vestibulopathies, however, changes DVA patients with degenerative cerebellar ataxias (CA) and its relation to VOR impairment these not yet evaluated. Our aim was assess the alterations CA evaluate vestibular function. 32 3 control groups: 13 unilateral bilateral vestibulopathy 21 age matched healthy volunteers were examined by clinical test, assessed video...
This study aimed to evaluate the ability of selected microRNAs as biomarkers atrial fibrillation (AF) in ischemic stroke patients comparison with other established biochemical biomarkers. A prospective case–control consecutive AF admitted a comprehensive center was conducted. The control group consisted no detected on prolonged (at least 3 weeks) Holter ECG monitoring. As potential AF, we analyzed plasma levels (miR-21, miR-29b, miR-133b, miR-142-5p, miR-150, miR-499, and miR-223-3p) 13 at...