- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Wheat and Barley Genetics and Pathology
- Chromosomal and Genetic Variations
- Plant Virus Research Studies
- COVID-19 Clinical Research Studies
- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Radiation Effects and Dosimetry
- Radioactive contamination and transfer
- Plant and Fungal Interactions Research
- Pediatric health and respiratory diseases
- Streptococcal Infections and Treatments
- Emergency and Acute Care Studies
- Genetic Mapping and Diversity in Plants and Animals
- Antimicrobial Resistance in Staphylococcus
- Ear Surgery and Otitis Media
- Antibiotic Use and Resistance
- Neonatal and Maternal Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Monetary Policy and Economic Impact
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2019-2024
Central Research Institute of Epidemiology
2015-2024
Central Research Institute
2020
Moscow State Agroengineering University named after V.P. Goryachkin
2014
The purpose of the study is to analyze patterns demonstrated by COVID-19 epidemic process in a megacity during increase, stabilization and reduction incidence, evaluate effectiveness prevention measures.Materials methods. comprehensive incorporating epidemiological, molecular genetic statistical research methods was conducted spread SARS-CoV-2 Moscow COVID- 19 pandemic.Results discussion. It found that exponential growth cases prevented due most stringent control restrictive measures...
Relevance. Influenza viruses have a high potential for genetic change. These are monitored annually around the world, including Russia, to determine dominant groups and select strains be included in influenza vaccines. Aims of study include: analysis circulation Russia 2019-2023, phylogenetic molecular hemagglutinin (HA) sequences virus strains, detection drug resistance mutations neuraminidase (NA) inhibitors M2-protein (M2) ion channel inhibitors. Materials methods. Biological samples...
Aim: to study the etiology of severe community - acquired pneumonia (SCAP) in adults Russian Federation. SCAP is distinguished by high mortality and socio economic burden. Both antimicrobial resistance are essential for appropriate antibiotic choice. Materials methods. A prospective cohort recruited with confirmed diagnosis admitted multi word hospitals six cities 2014-2018. Etiology was routine culture blood, respiratory (sputum, endotracheal aspirate or bronchoalveolar lavage) when...
Chronic heart failure (CHF) is one of the most common comorbidities in elderly patients with community-acquired pneumonia (CAP). The aim this study was to investigate etiology CAP concomitant CHF. Methods . This prospective observational involved adult hospitalized and confirmed by chest X-ray. Sputum samples or oropharyngeal swabs, blood urine were collected all eligible before starting therapy systemic antibiotics. cultured for «typical» bacterial pathogens, such as Streptococcus...
Group A streptococcal infections dominate among invasive infections, with the major causative agent, Streptococcus pyogenes, being quite stable in environment and bearing a large number of chromosome encoded pathogenicity factors or transmitted by horizontal transfer through bacteriophages. Different genetic variants S. pyogenes can have different set able to change during pathogen evolution determine virulence level for specific isolate. With short incubation period, disease proceed...
Журнал для непрерывного медицинского образования врачей ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ РезюмеДеструктивная пневмония -один из вариантов осложненного течения внебольничной пневмонии, характеризующийся образованием некротических полостей в легких.Частота встречаемости этой патологии у детей остается высокой, а этиологическая диагностика нередко затруднена
Introduction. SARS-CoV-2 can be transmitted by infected people without or with mild symptoms of acute respira-tory infection (ARI). Monitoring based on nucleic acid amplification techniques is used to measure the prevalence ARI pathogens and assess effectiveness preventive measures.The aim causing ARIs viral etiology, influenza, COVID-19 among individuals throughout age groups, trace changes in epidemic situation weekly monitoring during inter-epidemic period at beginning a typical season,...
Background. Bacterial superinfection is one of the most common and potentially lethal complications in severely critically ill patients with COVID-19. Objectives. To determine colonisation time frame spectrum potential bacterial pathogens respiratory samples from severe critical COVID-19, using routine culture polymerase chain reaction (PCR) tests. Methods. A prospective observational study was conducted on aged ≥18 years confirmed COVID-19 who were admitted to or transferred intensive care...
Objective. To study the etiology of community-acquired pneumonia (CAP) in adult hospitalized patients after COVID-19 pandemic. Materials and Methods. The prospective multicenter included 18 years older with confirmed diagnosis CAP admitted to 6 hospitals different regions Russia from July November 2023. Etiology was by respiratory samples (sputum, tracheal aspirate) culture, blood culture (severe cases), urinary antigen tests (Legionella pneumophila serogroup 1, Streptococcus pneumoniae)....
The Central Research Institute of Epidemiology Rospotrebnadzor presents priority data obtained from the largescale population PCR-based study changes in rates circulation SARS-CoV-2 among relatively healthy residents Moscow and Region.
Using sequences of mobile genetic elements in order to mark polymorphic sites their insertion might be the most effective approach identify specific features gene pools different groups organisms and control dynamics, which is especially important dealing with agricultural species.Sireviruses (Pseudoviridae) one oldest LTR-retrotransposons are widespread throughout plant kingdom.SIRE-1 largest detailed studied retrotransposon.Its analysis showed that insertions retroelement (particularly...
A comparative analysis was carried out of the amplification product spectra received in polymerase chain reaction with use both animal (cattle, sheep and horse breeds) plant (rice varieties) DNA flank retrotransposon PawS5 R173 family as a primer. The breed-specific traits animals variety-specific rice were revealed amplicons spectra. possible reasons for presence genomes plants homologous nucleotide sequences associated retrotransposon, their polymorphism efficiency an anchor polylocus...
Using sequences of mobile genetic elements in order to mark polymorphic sites their insertion might be the most effective approach identify specific features gene pools different groups organisms and control dynamics, which is especially important dealing with agricultural species. Sireviruses ( Pseudoviridae ) one oldest LTR-retrotransposons are widespread throughout plant kingdom. SIRE-1 largest detailed studied retrotransposon. Its analysis showed that insertions retroelement...
Aim. Establish genetic characteristics, carry out phylogenetic analysis and determination of molecular markers resistance to etiotropic preparations against influenza A/H3N2 В viruses that had circulated in Russia 2013 - 2015. Materials methods. 80 biological samples containing virus RNA 31 were studied. Sequencing PCR fragments was carried ABI-3100 PRIZMTM GeneticAnalyzer (AppliedBiosystems, USA) using MiSeq (Illumina, USA). Data treatment CLC v.3.6.5., DNASTAR BioNumerics v.6.5. programs....
In this paper we study whether financial frictions should be accounted for in a DSGE model of Russian economy. We compare the baseline two-sector model small open economy with its version extended by accelerator and another which assumes an agency problem between bankers depositors. Using calibrated versions these models, show how assumptions regarding peculiarities market change transmission mechanisms macroeconomic shocks. Specifically, responses investment consequently other variables...