A5042064788- Essential Oils and Antimicrobial Activity
- Ginger and Zingiberaceae research
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Medicinal Plants and Neuroprotection
- Piperaceae Chemical and Biological Studies
- Curcumin's Biomedical Applications
- Computational Drug Discovery Methods
- Ethnobotanical and Medicinal Plants Studies
- Pharmacological Effects of Natural Compounds
- Traditional and Medicinal Uses of Annonaceae
- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Medicinal Plants
- Andrographolide Research and Applications
- Medicinal Plant Research
- GABA and Rice Research
- Genomics, phytochemicals, and oxidative stress
- Phytochemical Studies and Bioactivities
- Advanced Chemical Sensor Technologies
- Inflammatory mediators and NSAID effects
- Natural Antidiabetic Agents Studies
- Bioactive Compounds and Antitumor Agents
- Drug-Induced Hepatotoxicity and Protection
- Plant tissue culture and regeneration
Siksha O Anusandhan University
2016-2025
Zoological Survey of India
2024
Odisha University of Agriculture and Technology
2019
Central Rice Research Institute
2016
Utkal University
2014
Cinnamomum tamala (Buch.-Ham.) T.Nees & Eberm., or Indian Bay Leaf, is a well-known traditional ayurvedic medicine used to treat various ailments. However, the molecular mechanism of action essential oil (CTEO) against non-small cell lung cancer (NSCLC) remains elusive. The present study aims decipher targets and CTEO in treating NSCLC. GC-MS analysis detected 49 constituents; 44 successfully passed drug-likeness screening were identified as active compounds. A total 3961 4588...
The essential oil extracted from rhizome and leaf of Curcuma angustifolia Roxb. (Zingiberaceae) was characterised by gas chromatography-mass spectrometry (GC-MS). GC-MS analysis revealed the presence 32 35 identified constituents, comprising 92.6% 92% total oil, respectively. Curzerenone (33.2%), 14-hydroxy-δ-cadinene (18.6%) γ-eudesmol acetate (7.3%) were main components in oil. In curzerenone (72.6%), camphor (3.3%) germacrone found to be major constituents. Antioxidant capacities assessed...
Inflammatory diseases contribute to more than 50 % of global deaths. Research suggests that network pharmacology can reveal the biological mechanisms underlying inflammatory and drug effects at molecular level. The aim study was clarify mechanism
Mesosphaerum suaveolens (L.) Kuntze (Syn. Hyptis Poit.) is a wild essential-oil-bearing plant having multiple uses in traditional medicine, perfumery, food, agriculture, and pharmaceutical industries. The present paper the first report on vitro anti-inflammatory effects of leaf essential oil M. (MSLEO) unravels its molecular mechanism LPS-stimulated RAW 264.7 macrophage cells. GC-MS analysis (EO) isolated from leaves by hydro-distillation led to identification 48 constituents, accounting for...
The essential oils of three medicinally important Curcuma species (Curcuma alismatifolia, aromatica and xanthorrhiza) were extracted using conventional hydro-distillation (HD) solvent free microwave extraction (SFME) methods. volatile compounds from the rhizome subsequently analysed by GC-MS. isolation each was carried out following six principles green comparison made between their chemical composition, antioxidant, anti-tyrosinase anticancer activities. SFME found to be more efficient than...
The present research deals with studying the phytoconstituents, antioxidant potential, cytotoxicity and anti-inflammatory activities of Zingiber zerumbet rhizome essential oil (ZZEO). A total 29 components were identified using GC-MS accounting for 94.68% EO composition. ZZEO was characterized by sesquiterpenes, comprising 83.11% composition zerumbone (68.18%) α-Humulene (11.72%) as major compounds. DPPH FRAP assays showed IC50 values 83.90±0.05 mg/ml 1.98±0.04 respectively. in silico PASS...
Eulophia nuda Lndl., a terrestrial medicinal orchid, is well known for its ethnomedicinal applications in treating bronchitis, tuberculosis, tumors, snake bites, and arthritis. This study aimed to identify the phytoconstituents of extract (ENE) evaluate antioxidant, antityrosinase, anticancer, antimicrobial activities. UPLC‐QTOF‐MS analysis identified 33 compounds, 31 which were reported first time, with phenols, terpenoids, carboxylic acids as dominant classes. ENE exhibited strong...
Hedychium coronarium Koen. (Zingiberaceae) is traditionally used as medicine in countries such India, China, and Vietnam for treatment of various ailments including cancer. However, spite its implied significance cancer regimes, there are no reports so far involving the anticancerous attributes H, ethanol extract (HCEE) on cells a more comprehensive study mechanism still lacking.The cytotoxicity HCEE was evaluated by MTT clonogenic survival assay. Annexin V/propidium iodide (PI), Hoechst...
Inflammation is caused by a cascade of events, one which the metabolism arachidonic acid, that begins with oxidation enzyme 5-lipoxygenase. 5-Lipoxygenase (5-LOX) plays an important role in inflammation process synthesizing leukotrienes and several lipid mediators has emerged as possible therapeutic target for treatment inflammatory diseases such asthma rheumatoid arthritis. Most existing 5-LOX inhibitors are synthetic exhibit adverse side effects. In view this, there need to search...
is an essential oil bearing plant extensively used in the traditional system of medicine several countries. Previous research has revealed