- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cutaneous lymphoproliferative disorders research
- CNS Lymphoma Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Mast cells and histamine
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Histiocytic Disorders and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Oral and Maxillofacial Pathology
- T-cell and Retrovirus Studies
- Erythrocyte Function and Pathophysiology
- Vascular Tumors and Angiosarcomas
- Congenital Heart Disease Studies
- Ocular Diseases and Behçet’s Syndrome
- Hematological disorders and diagnostics
- Dermatological and Skeletal Disorders
- Eosinophilic Esophagitis
- Tumors and Oncological Cases
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
Hospital Universitario Virgen del Rocío
2015-2025
Instituto de Biomedicina de Sevilla
2016-2025
Universidad de Sevilla
2016-2025
Aix-Marseille Université
2018
Hospital Juan Ramón Jiménez
2003-2013
NeuroSurgical Research Foundation
1992
Women's and Children's Hospital
1992
Bunge (United States)
1973
Breast implant-associated anaplastic large cell lymphoma (BI-ALCL) is a rare T-cell that arises around breast implants. Most patients manifest with periprosthetic effusion, whereas subset of develops tumor mass or lymph node involvement (LNI). The aim this study to describe the pathologic features nodes from BI-ALCL and assess prognostic impact LNI. Clinical findings histopathologic were assessed in 70 BI-ALCL. LNI was defined by histologic demonstration ALCL nodes. Fourteen (20%) had LNI,...
Plasmablastic lymphoma is a recently described neoplasm arising in the oral cavity and jaws of HIV-infected patients, frequently related to Epstein–Barr virus, with morphology immunophenotype that can cause diagnostic difficulties pathologist. Although initially localized, it usually behaves aggressively. The use highly active antiretroviral therapy combination chemo- radiotherapy may provide way improving its prognosis. Infection HIV increases risk developing non-Hodgkin's lymphomas (NHL),...
Summary Nodal peripheral T‐cell lymphoma (PTCL) with a T follicular helper phenotype (PTCL‐TFH) is new type of PTCL. We aimed to define its clinical characteristics and prognosis compared PTCL not otherwise specified (PTCL‐NOS) angioimmunoblastic (AITL). This retrospective observational study included 175 patients diagnosed between 2008 2013 in 13 Spanish sites. Patient diagnosis was centrally reviewed, were reclassified according the World Health Organization (WHO) 2016 criteria: 21 as...
This study was designed to describe the surgical anatomy and histology of rabbit anorectum comparing it that humans, in order decide whether can be a good experimental model for research proctology.This anorectal region performed on six female New Zealand white rabbits, weighting between 2.5-2.9 kg. An autopsy immediately after sacrificing animal an anatomical histological description performed.The mean rectum anal canal lengths were 7.2 cm 0.9 cm, respectively. The macroscopic showed...
Castleman disease (CD) is a rare benign lymphoproliferative disorder commonly described as hypervascular mass that causes progressive lymph node enlargement. Head and neck involvement occurs only in 15% to 20% of cases. The recommended treatment solitary CD radical resection. Few reports have the use angiographic study preoperative embolization minimize intraoperative risk hemorrhage. We report clinical case large painless, slow-growing located 34-year-old woman. Contrast-enhanced computed...
To assess the viability of orthotopic and heterotopic patient-derived pancreatic cancer xenografts implanted into nude mice.This study presents a prospective experimental analytical follow-up development tumours in mice upon implantation human adenocarcinoma samples. Specimens were obtained surgically from patients with pathological diagnosis adenocarcinoma. Tumour samples transplanted three different locations (intraperitoneal, subcutaneous pancreatic). Histological analysis...
Hereditary anal sphincter myopathy is rare. We present a family with one affected member proctalgia fugax, constipation and internal hypertrophy. Ultrastructural findings show vacuolization of smooth muscle cells without the characteristic polyglucosan inclusion. Further relief symptoms was obtained using an oral calcium antagonist. Based on clinical presentation, endosonography morphological findings, we consider our case histological variant vacuolar originally described.
Two siblings presented a similar disorder characterized by the following features: onset during second decade or at beginning of third, migrainous attacks with focal paresthesias, Jacksonian epileptic fits postictal paralysis, temporal and grand mal seizures, repeated status epilepticus, deficits, visual field defects, aphasic apraxic disturbances, progressive dementia. In both cases, arteriograms suggested possibility vascular malformation; right cavernoma was also discovered in one...
Extraosseous plasmacytoma (EOP) is an uncommon malignant tumour that characterised by the monoclonal proliferation of abnormal plasma cells in soft tissue; however, EOP lacks defining features multiple myeloma or medullary plasmacytoma. Although majority lesions occur head and neck, parotid gland extremely uncommon. The present study aimed to explore clinical plasmacytoma, addition diagnostic therapeutic options for its management. Using Medline database, a search was conducted articles...
Abstract We investigated the clinicopathological features and prognostic factors of patients with peripheral T‐cell lymphoma (PTCL) in 13 sites across Spain. Relevant clinical antecedents, CD30 expression staining pattern, indices using International Prognostic Index Intergruppo Italiano Linfomi system, treatments, outcomes were examined. A sizeable proportion 175 had a history immune‐related disorders (autoimmune 16%, viral infections 17%, chemo/radiotherapy‐treated carcinomas 19%). The...
Obstructive sleep apnea syndrome (OSAS) frequently develops in patients with craniosynostosis and associated midfacial stenosis. In the past, conservative measures or tracheostomy have been used to manage this condition. Although course of OSAS these is multifactorial, a major factor narrow nasopharyngeal space. Aggressive surgical intervention enlarge space can reduce severity therefore avoid need for tracheostomy. Surgical approaches include adenotonsillectomy, uvulopalatopharyngoplasty,...
Phlebosclerotic colitis is a rare condition with high mortality. It has been seen almost exclusively in Asian patients who are ≥ 60 years old, slight male predominance. Although it predominantly affects the right colon and seems to be related some cases using natural herbal medicines, neither its etiology nor pathogenesis known.We present an extremely case of 62-year-old Spanish white man patient non-Asian ethnicity no history medications, was diagnosed phlebosclerotic submucosal veins.To...
A 12-month-old infant was admitted to hospital after his parents had noticed a painless tumour involving left hip over the previous 3 weeks. Examination showed hard mass with indistinct borders and no inflammatory signs. Neither lymphadenopathy nor hepatosplenomegaly detected. full blood count only thrombocytosis, platelet 600 × 109/l. No blast cells or leucoerythroblastic features were seen in film. Other tests unremarkable. Imaging studies plain radiography magnetic resonance imaging 47 58...