- Infectious Diseases and Mycology
- Multiple Myeloma Research and Treatments
- Antifungal resistance and susceptibility
- Chronic Myeloid Leukemia Treatments
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Economic and Financial Impacts of Cancer
- Histone Deacetylase Inhibitors Research
- Plant Pathogens and Fungal Diseases
- Reproductive Health and Contraception
- Renal cell carcinoma treatment
- Cancer Genomics and Diagnostics
- American Constitutional Law and Politics
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Renal and related cancers
- Reproductive Health and Technologies
- Lymphoma Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Viral gastroenteritis research and epidemiology
- Cancer Treatment and Pharmacology
- Cancer Immunotherapy and Biomarkers
- Systemic Lupus Erythematosus Research
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Bowel Disease
- Acute Myeloid Leukemia Research
Institute of Group Analysis
2023
Columbia University
2020
Analysis Group (United States)
2014-2017
Immune-mediated inflammatory diseases including rheumatoid arthritis (RA), psoriatic (PsA), ankylosing spondylitis (AS), non-radiographic axial spondylarthritis (nr-axSpA), atopic dermatitis (AD), ulcerative colitis (UC), and Crohn's disease (CD) pose a substantial burden on patients their quality of life. Upadacitinib is an orally administered, selective, reversible Janus kinase inhibitor indicated for seven conditions, but data its safety versus other active treatments are limited. A...
The randomized phase III KEYNOTE-522 trial demonstrated that addition of pembrolizumab to neoadjuvant chemotherapy provided a significant improvement in event-free survival and favorable trend overall for high-risk early-stage triple-negative breast cancer (eTNBC). This analysis evaluated the cost-effectiveness combination with as treatment continued single-agent adjuvant after surgery vs. patients eTNBC USA.The was conducted from US third-party public healthcare payer perspective. A...
In the medical field, conscientious objection is claimed by providers and pharmacists in an attempt to forgo administering select forms of sexual reproductive healthcare services because they state it goes against their moral integrity. Such claim may include refusing administer emergency contraception individual with a need that time-sensitive. Conscientious first defined, then historical context provided on field’s involvement issue. An explanation contraception’s physiological effects...
Background Second targeted therapies for metastatic renal cell carcinoma (mRCC) include mammalian target of rapamycin inhibitors (mTORis) and tyrosine kinase (TKIs). This observational study compares overall survival (OS) progression-free (PFS) patients treated with everolimus (an mTORi) axitinib (a TKI) following first TKI, assesses the impact type duration TKI on relative effectiveness these second therapies. Methods Retrospective reviews medical records were conducted by oncologists or...
Rotavirus (RV) vaccines have demonstrated substantial effectiveness in reducing the healthcare burden caused by gastroenteritis (RVGE) worldwide. This study aims to understand differential impact of RV vaccination RVGE children under 7 years old China. A Markov Model was used investigate health introducing two different into Chinese population. The analysis conducted for RV5, a live pentavalent human-bovine reassortant vaccine, and Lanzhou Lamb (LLR), live-attenuated monovalent separately,...
e19509 Background: Lenalidomide maintenance therapy after autologous stem cell transplant (ASCT) in the first-line treatment has been shown to improve progression-free survival (PFS) and overall (OS) multiple myeloma (MM) patients (pts). This study assessed impact of FDA approval lenalidomide on total healthcare costs a US health plan. Methods: A model was developed estimate incremental (additional) plan (in 2016 USD) for each year first 3 years monotherapy (R) approval. The number post-ASCT...