A5028219273- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Heart Failure Treatment and Management
- Ferroptosis and cancer prognosis
- 3D Surveying and Cultural Heritage
- Mesenchymal stem cell research
- Cell death mechanisms and regulation
- RNA modifications and cancer
- Traditional Chinese Medicine Analysis
- Cancer, Hypoxia, and Metabolism
- Cancer Cells and Metastasis
- Health Literacy and Information Accessibility
- HER2/EGFR in Cancer Research
- Conservation Techniques and Studies
- Infrastructure Maintenance and Monitoring
- Social Media in Health Education
- Ginseng Biological Effects and Applications
- Offshore Engineering and Technologies
- Additive Manufacturing and 3D Printing Technologies
- Sustainable Building Design and Assessment
- Land Use and Ecosystem Services
- Cancer, Lipids, and Metabolism
- Synthesis of Organic Compounds
- Control Systems in Engineering
- Protein Degradation and Inhibitors
Tianjin Medical University
2022-2025
Second Hospital of Tianjin Medical University
2022-2025
Nantong University
2025
Nanjing Forestry University
2022-2023
Sichuan University
2023
Xian Central Hospital
2021
Shanghai Normal University
2019-2020
Taiyuan University of Technology
2012-2020
Henan Polytechnic University
2015
Handan College
2015
Triptolide, a purified diterpenoid triepoxide compound derived from traditional Chinese medicine, Tripterygium wilfordii HOOK. f (TWHf), has been used in the treatment of autoimmune and inflammatory diseases. However, toxicity triptolide limits its application to great extent. In present study, we treated human normal liver L-02 cells (L-02 cells) with vitro investigated toxic effects. The cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay...
Polylactic acid (PLA) surgical suture can be absorbed by human body. In order to avoid site infections (SSIs), the drug is usually loaded on PLA suture, and then release directly wound. Because different types of wounds heal at times, it needed control rate consistent wound healing time. Two biopolymers, polyglycolide (PGA) polycaprolactone (PCL), were selected as carrier ciprofloxacin (CPFX) drug, CPFX-PCL/PGA was coated suture. The degradation drug-carrier controlled adjusting proportion...
Abstract Urbanization is inevitable in both developing and developed countries. However, this growth transformation of the urban area can pose a significant threat to cultural heritage, which sensitive component environment. As cities modernize change, risk irreparable loss heritage exists. Therefore, taking steps protect preserve these sites for posterity crucial. To better decision-makers must rapidly assess impact urbanization on while maintaining balance between preservation growth. This...
Abstract Background Self-efficacy and mental health present mutually influencing relationships in caregivers of patients with heart failure (HF). There is currently a lack understanding the synergistic developmental mechanisms self-efficacy, anxiety, depression caregivers. The purpose study was to examine individual dual trajectories caregiver during first three months after discharge HF. Methods A prospective cohort conducted from June 2022 May 2024, four tertiary hospitals Tianjin, China....
Lysine-specific histone demethylase 1 (LSD1) is an attractive target for malignancies therapy. Nevertheless, its role in hepatocellular carcinoma (HCC) progression and the potential of inhibitor HCC therapy remains unclear. Here, we show that LSD1 overexpression human tissues associated with poor patient survival. ZY0511, a highly selective potent LSD1, suppressed cell proliferation vitro tumor growth cell-derived patient-derived xenograft models vivo. Mechanistically, ZY0511 induced mRNA...
Gastric cancer is one of the most common malignancies with a high mortality rate world. This study intends to make clear role and mechanism Scutellarin (Scu), flavonoid isolated from Erigeron breviscapus (Vant.) Hand.-Mazz, in regulating evolvement gastric cancer. We selected different doses Scu treat cells (MGC-803 AGS). Then, cell counting kit-8 (CCK8) assay was conducted verify proliferation tumor cells, while flow cytometry adopted test apoptosis rate. Meanwhile, Western blot examine...
Abstract Owing to the lack of appropriate protection measures, natural and human factors have led deterioration rockeries, which are a distinct cultural heritage with both aesthetic historical value an essential component Chinese classical gardens. The state rockeries is evaluated by craftsmen who assess damage levels based on their experience. While this common practice, it lacks standardization, may cause great uncertainty that influences efficiency rockeries. preservation risk mitigation...
The basalt fibers/poly (lactic acid) composites, as a kind of green environment friendly materials, were prepared by vacuum perfusion method. effect silane coupling agent KH550 on the interface BFs/PLA composites was analyzed. We observed microstructure surface BFs treated and explored chemical reaction among KH550, PLA. succeeded in linking PLA enhanced interfacial bonding strength between matrix. crystalline properties KH550-treated better than untreated composites. mechanical test...
Based on the rockery photos of 10 classical gardens including world cultural heritage, this paper incorporates combined analysis and comparison constituent elements (rockeries, buildings plants) scenic surfaces, probes into fractal characteristics landscaping through theory dimension (FD) value software. Studies have shown that quantitative evaluation data visual complexity (FD, i.e., dimension) can characterize contour morphology surface rockeries. The relevant results are as follows: (1)...
Abstract We have investigated the antiproliferative effects of TBIDOM (N-(4-(2,2,2-trifluoroethyl) benzylidene) (7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl) meth-anamine) and explored its possible mechanisms on human hepatocellular carcinoma SMMC-7721 cells. The proliferative status cells treated with was measured by colorimetric MTT assay. Cellular apoptosis analysed using Hoechst 33342 staining flow cytometry. Reduction mitochondrial membrane potential (Δψm)...
Here we investigated the establishment of multicenter cooperative treatment groups in China, as well radiotherapy compliance and effectiveness among children with renal tumors. Medical records were reviewed for 316 tumors diagnosed by a group from 14 hospitals China 1998 to 2012. Median patient age was 29.5 months (range, 2–173 old), male-to-female ratio 1.4 : 1. After median follow-up 22 1–177 months), five-year event-free survival rates 72% overall; 76.1% favorable histology (251 cases);...
The aim of this study was to observe the effects re-combinant human endostatin on proliferation and apoptosis mouse gastric cancer cells, explore some possible mechanisms recom-binant inhibition cancer. A murine xenograft model established. total 20 mice were divided into two groups (control experimental groups). expression c-Myc basic fibroblast growth factor (bFGF) determined by reverse transcription-polymerase chain reaction, Western blotting, immu-nohistochemical staining methods. Tumor...
Background Although a growing number of studies have demonstrated that patients' health literacy is associated with outcomes, the exact relationship between them not clear. Aims and objectives The aim this study was to explore latent classes in patients heart failure analyze differences among different groups. Design Methods This cross-sectional survey. Patients diagnosed were selected from 3 tertiary hospitals Tianjin, China, March 2019 November 2019. We measured using Health Literacy Scale...
Hydrothermal reactions of molybdenum(III) oxide with isoquinoline under different pH values lead to two new octamolybdate-based polyoxometalates (POMs), namely, (C9H7NH)4(C9H7N)2[Mo8O26] (1) and (C9H7NH)4[(Mo8O26)(C9H7N)2]·2(H2O) (2), their structures were determined by single-crystal X-ray diffraction analysis. The compounds represent the first report [Mo8O26]4− based POMs associated ligand. Compound has 3D supramolecular framework on hydrogen bonds between [β-Mo8O26]4− fragment protonated...
This paper studies the microstructure of 16 group samples from three different sites North-west region in P. R. China. Pictures were processed with imaging processing program to acquire geometer parameter and fractal dimension pores. The range pores’ is between 1.816~1.936. pore distribution function unsaturated soil established based on geometry theory. water loess under natural moisture analyzed. relationships collapsibility coefficient porosity pores are analyzed method regression...