Abstract It is indicated that lipids profiles are associated with carotid plaque and Atherosclerosis. However, studies about the relationship between serum lipid composition in Chinese Population limited. We conducted a cross-sectional study among 3,214 participants January 2015 December 2017 China, to investigate association various prevalence of plaque. Logistic regression model was used plasma odds Analysis covariance (ANCOVA) compare mean different number artery plaques. HDL-C, Non-HDL-C...

Background/aim: Patients with elevated intracranial pressure (ICP) tend to have optic disc edema and a thicker nerve sheath diameter (ONSD). However, the cut-off value of height (ODH) for evaluating ICP is not clear. This study was conducted evaluate ultrasonic ODH investigate reliability ONSD ICP. Methods: suspected having increased who underwent lumbar puncture were recruited. measured before puncture. divided according normal We analyzed correlations between ODH, ONSD, points...

Tissue-specific alternative splicing (AS) is emerging as one of the most exciting types mechanisms associated with organ development and disease. In auditory system, many hearing-related genes undergo AS, errors in this process result syndromic or non-syndromic hearing loss. However, little known about factors directing AS inner ear. present study, we identified a novel RNA-binding protein, Rbm24, which was critically involved regulating inner-ear-specific AS. Rbm24 deletion resulted loss...

Mere15 is a novel polypeptide from Meretrix meretrix Linnaeus with cytotoxicity in solid cancer cells. In this study, we investigated its activity on human K562 chronic myelogenous leukemia inhibited the growth of cells IC50 values 38.2 μg/mL. also caused concentration dependent induction apoptosis, overproduction reactive oxygen species and loss mitochondrial membrane potential. Moreover, arrested cell cycle progression at G0/G1 phase manner. addition, disassembly microtubule cytoskeleton...

Background:Several studies have shown that multidrug transporters, such as P-glycoprotein (PGP), are involved in cell resistance to chemotherapy and refractory epilepsy. The p38 mitogen-activated protein kinase (MAPK) signaling pathway may increase PGP activity. However, p38-mediated drug associated with is unclear. Here, we investigated doxorubicin-induced human leukemia K562 cells.Material/Methods:The expression of was detected by RT-PCR, Western blot, immunocytochemistry. Cell viability...

Background: Previous studies have indicated that white blood cells (WBCs) might contribute to the development of atherosclerosis. However, associations WBCs and WBC subgroups with carotid atherosclerotic plaque (CAP) not been compared. Methods: A cross-sectional study including 3,569 healthy Chinese adults was conducted between January 2016 December 2018 in Zhengzhou, China, explore subtypes presence, severity, types CAPs. Fasting peripheral venous collected for measurement total subtype...

Poly(m-carborane-siloxanes) with various pendant groups (P15-P46) were synthesized via polycondensation of m-carborane-containing disilanols (1-4) and highly active bisureidosilanes (5 6). The obtained polymers exhibit controlled molecular weight by carefully adjusting the monomer ratio. Standard spectroscopic techniques including FTIR NMR utilized to characterize these satisfactory results obtained. TGA analysis indicated that thermal cyclization polysiloxanes under nitrogen was greatly...

Purpose: This study evaluated the association among plasma concentration of ticagrelor, ARC124910XX, aspirin, and salicylic acid with risk recent bleeding in patients acute coronary syndrome. To this end, we developed an accurate model to predict bleeding. Methods: A total 84 included cohort between May 2021 November 2021. The factors were identified by univariate multivariate analyses, statistically significant analysis nomogram. We used calibration curve receiver operating characteristic...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Li M, Liu P, Wang H, et al. Computed tomography-guided iodine-125 radioactive seed implantation in small-cell lung cancer: A retrospective study. Journal of Contemporary Brachytherapy. 2022;14(6):536-541. doi:10.5114/jcb.2022.123973. APA Li, M., Liu, P., Wang, H., B., Zhou, J., & Jin, Y. (2022). Brachytherapy, 14(6), 536-541. https://doi.org/10.5114/jcb.2022.123973 Chicago Mengjie, Peng Huan Biao Jie Yuzhen and...

Object: To investigate the levels of serum interleukin-10 (IL-10) and IL-17 in papillary thyroid carcinoma (PTC) their relationship with prognosis. Method: 120 PTC patients who underwent radical mastectomy Department Thyroid Mammary Surgery Cangzhou Central Hospital from January 2018 to April 2019 were randomly selected as experimental group, healthy people matched 1:1 hospital physical examination center same period control group according sex, age body mass index group. Compare IL-10...

We assessed the efficiency of point-of-care (POC) tests in emergency department (ED) by comparing them with international standard. recorded turnaround times (TATs) for processing laboratory biomarkers to assess from 17 EDs national/regional hospitals. also compared patient components between national and regional Although enrolled hospitals expanded their EDs, they contained only five POC machines among them. The P50 (P25, P75) TATs was 47 min (39, 55.5 min) cardiac troponin T, which much...

Impaired fasting glucose (IFG) is associated with an increased risk of multiple diseases. Therefore, the early identification and intervention IFG are particularly significant. Our study aims to construct validate a clinical laboratory-based nomogram (CLN) model for predicting risk.This cross-sectional collected information on health check-up subjects. Risk predictors were screened mainly by LASSO regression analysis applied CLN model. Furthermore, we showed examples applications. Then,...

To analyze the potential association between occlusion features and incidence of temporomandibular joint (TMJ) arthralgia in patients with partial dentures.A total 101 denture wearers were collected, 45 unilateral TMJ diagnosed according to Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Binary logistic regression analysis was adopted. The asymptomatic group (n = 45) quantified as 0, while 56) 1. In total, 13 variables analyzed: gender, age, number prosthetic teeth, dentition...

Objective To evaluate the efficacy and safety of imatinib in chronic myeloid leukemia (CML) patients analyse factors affecting survival. Methods 135 CML receiving were evaluated for hematologic, cytogenetic, molecular responses adverse events. Results The median follow-up was 20 (range 3-67) months. rate cumulative complete hematological response (CHR), major cytogenetic (MCyR), response( CCyR ) (CMoR) phase 97.9 %, 78.3 72.2 % 35.1%, respectively.These rates significantly higher than...

Objective To evaluate it’s prognosis according to the follow-up statistics of coronary reimplantation anomalous left artery originating from pulmonary artery(ALCAPA). Methods Analyze preoperative, peri-operative and postoperative data 20 ALCAPA patients having undergone reimplantation. Results After reimplantation, patient’s cardiothoracic ratio was obviously decreased, degree myocardial ischemia improved electrocardiogram, ventricular ejection fraction fractional shortening...

Objective To identify prognostic factors for mortality in patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). Methods A retrospective study was conducted 138 initiated CRRT due to AKI who were admitted the Emergency Intensive Care Unit of Xinhua Hospital Affiliated Shanghai Jiaotong University School Medicine from May 2012 December 2016. According whether these survived after 28 days, they divided into death group (58 cases) and (80 cases)....