A5078798144- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Advanced Fluorescence Microscopy Techniques
- Aortic Disease and Treatment Approaches
- Optical Imaging and Spectroscopy Techniques
- Cancer-related molecular mechanisms research
- Photoacoustic and Ultrasonic Imaging
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Disease and Adiposity
- Circular RNAs in diseases
- Cardiac electrophysiology and arrhythmias
- Intensive Care Unit Cognitive Disorders
- RNA modifications and cancer
- Nosocomial Infections in ICU
- interferon and immune responses
- Cardiovascular Issues in Pregnancy
- Respiratory Support and Mechanisms
- Coronary Interventions and Diagnostics
- RNA Research and Splicing
- Pulmonary Hypertension Research and Treatments
- Peripheral Artery Disease Management
- Atrial Fibrillation Management and Outcomes
- Viral Infections and Vectors
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
Southern Medical University
2018-2024
Guangdong Academy of Medical Sciences
2022-2024
Guangdong Provincial People's Hospital
2019-2024
South China Sea Institute Of Oceanology
2024
South China University of Technology
2024
Expression of the long non-coding RNA taurine-upregulated gene 1 (TUG1) is associated with various aggressive tumors. The present study aimed to investigate biological function TUG1 in regulating apoptosis, proliferation, invasion and cell cycle distribution human glioma U251 cells. Lentivirus‑mediated TUG1‑specific microRNA was transfected into cells abrogate expression TUG1. Flow cytometry analysis used examine apoptosis Cellular proliferation examined using Cell Counting Kit‑8 (CCK‑8)...
Mechanical ventilation (MV) is an important lifesaving method in intensive care unit (ICU). Prolonged MV associated with ventilator pneumonia (VAP) and other complications. However, premature weaning from may lead to higher risk of reintubation or mortality. Therefore, timely safe important. In addition, identification the right patient performing a suitable process necessary. Although several guidelines about have been reported, compliance these unknown. aim this study explore variation...
The rupture of coronary atherosclerotic plaque (CAP) and the resulting intracoronary thrombosis account for most acute syndromes. Thus, early identification risk assessment CAP is crucial timely medical intervention. In this study, we propose a quantitative label-free method human using multiphoton microscopy (MPM) three-dimensional (3D) image analysis techniques. By detecting intrinsic MPM signals, microstructures collagen elastin fibers within normal CAP-lesioned artery walls were imaged....
Junhai Hao, Jiaxin Li, Hanxiao Zhang, Jia Chen, Miaoxian Fang, Meifen Wu, Bowen Gu, Yingkai Xiao, Liming Lei
Aortic dissection is a severe cardiovascular condition associated with high mortality rates, particularly in cases of Stanford type A aortic (TAAD). Myocardial infarction non-obstructive coronary arteries (MINOCA) following surgery for TAAD rare but potentially fatal. : 69-year-old woman presented sudden chest pain and was diagnosed acute TAAD. Emergency performed, during which complications arose, including significant hemodynamic instability. Despite efforts to manage the patient's...
Objective To observe the effect of TUG1 gene silencing on glioma cell growth and apoptosis. Methods A slow virus vector pLenti6.3-EGFP carrying shRNA-TUG1 was constructed then transfected into human U251 cells. The expression levels LncRNA in cells were detected by using real-time fluorescence quantitative PCR. inhibitory interference observed. Flow cytometry CCK-8 assay used to interfering proliferation apoptosis. Results The results fluorescent PCR detection showed that as for...
Pregnant women with aortic dissection are hemodynamically outmost complex patients. The two major diagnoses that should be considered in pregnant patients congenital heart disease (CHD) and acute type A presenting postoperative right ventricular dysfunction pulmonary thromboembolism infarction. We present a rare case of CHD dissection, which was diagnosed by computed tomography angiography treated percutaneous coronary intervention.
Cardiovascular disease, especially coronary heart disease (CHD) caused by atherosclerosis, has been a leading cause of death world-wide. Traditional methods diagnosing CHD, including CT angiography and histopathological examination, are limited either the low image resolution or time-consuming sample preparation. Spectrum- time-resolved multiphoton microscopy potential to circumvent this problem because it can not only interrogate three-dimensional structure arterial intima but also reveal...