A5100650400- Pharmacological Effects of Natural Compounds
- Intensive Care Unit Cognitive Disorders
- Pharmacogenetics and Drug Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Traditional Chinese Medicine Studies
- Long-Term Effects of COVID-19
- Advanced Neuroimaging Techniques and Applications
- Cervical Cancer and HPV Research
- Veterinary Oncology Research
- Pancreatic and Hepatic Oncology Research
- Perovskite Materials and Applications
- Anesthesia and Neurotoxicity Research
- Quantum Dots Synthesis And Properties
- Epilepsy research and treatment
- Pesticide and Herbicide Environmental Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Circular RNAs in diseases
- Infectious Diseases and Mycology
- Sepsis Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Glioma Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Machine Learning in Healthcare
- Therapeutic Uses of Natural Elements
Fujian Medical University
2021-2024
Guangxi Medical University
2022-2024
First Affiliated Hospital of GuangXi Medical University
2022-2024
Dalian University of Technology
2024
China Agricultural University
2015-2024
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2017-2023
National Taiwan University
2020-2023
Guangzhou University of Chinese Medicine
2019-2022
Union Hospital
2021
Guangdong Academy of Medical Sciences
2021
Abstract Chronic heart failure (CHF) is the final outcome of many cardiovascular diseases, and a severe health issue faced by elderly population. Mixed lineage kinase 3 (MLK3), member MAP3K family, associated with aging, inflammation, oxidative stress, related such as CHF. MLK3 has also been reported to play an important role in protecting against cardiomyocyte injury; however, its function myocardial fibrosis unknown. To investigate fibrosis, we inhibited expression MLK3, examined cardiac...
A general strategy for fabrication of high-quality inorganic CTLs on top an perovskite to achieve high efficiency and stability.
Papillomavirus (PV) mainly infects the squamous epithelium and may potentially lead to benign or even malignant cutaneous lesions. However, transforming ability has been identified in several types of PVs. In humans, papillomavirus (HPV) type 16 18 are most prevalent causative agents cervical cancer. Therefore, vaccines being developed protect against these types. For dogs, there have limited investigations into association different canine (CPV) genotypes with Understanding high-risk CPV...
Septic shock patients fundamentally require delicate vasoactive and inotropic agent administration, which could be quantitatively objectively evaluated by the vasoactive-inotropic score (VIS); however, whether dynamic trends of high-time-resolution VIS alter clinical outcomes remains unclear. Thus, this study proposes term Reduction Rate (VRR) to generalise tendency VIS, explore association VRR mortality for with septic shock.We applied static data predict ICU two models: long short-term...
A FA-assisted fast crystallization (FAAFC) method involving adding FA into an antisolvent to achieve homogeneous nucleation and a high-quality crystalline film.
Background Increased uric acid (UA) levels have been reported to be associated with poor clinical outcomes in several conditions. However, the prognostic value of UA patients infective endocarditis (IE) is yet unknown. Methods A total 1,117 IE were included and divided into two groups according current definition hyperuricemia (UA>420 μmol/L men >360 women): group (n=336) normouricemia (n=781). The association between level short-term examined. Results in-hospital mortality was...
Abstract The adsorption of paraquat (PQ) on starfish particles was investigated to calculate the kinetic, isotherm, and thermodynamic parameters. experiments were carried out as a function particle size adsorbent, adsorbent dosage, contact time, initial PQ concentration, stirring speed, temperature. kinetic data followed pseudo‐second‐order model, equilibrium well fitted by Langmuir isotherm model with maximum amount 10.235 mg g −1 at 288 K. Thermodynamic parameters, including standard Gibbs...
The efficacy of cyhalofop‐butyl with tank‐mixed adjuvants on barnyardgrass ( Echinochloa crus‐galli [L.] Beauv .), as well the physico‐chemical properties, absorption and translocation, was evaluated compared. experiment showed that treatments were approximately twofold more effective than alone at 2% (v/v) (silwet 625 0.05%). surface tension decreased droplets could spread automatically leaves after adding adjuvants. spreading speed increased significantly epidermal cells wax layer damaged...
Patients with heart disease often suffer from ischemia, which can be treated by reperfusion. However, this treatment lead to the development of ischemia/reperfusion (I/R) injury, an inflammatory condition that cause further damage. Dexmedetomidine (Dex), α2-adrenoceptor agonist, and microRNA (miR)-17-3p, have both been suggested alleviate I/R injury cardiac tissue inflammation. The aim present study was investigate whether Dex miR-17-3p could act together prevent injury. H9C2 cells, a...
BACKGROUND:Sepsis-induced myopathy (SIM) is a complication of sepsis that results in prolonged mechanical ventilation, long-term functional disability, and increased patient mortality. This study aimed to use bioinformatics analysis identify hub genes molecular pathways involved SIM, potential diagnostic or therapeutic biomarkers. MATERIAL AND METHODS:The Gene Expression Omnibus (GEO) database was used acquire the GSE13205 expression profile. The differentially expressed (DEGs) cases SIM...
Primary hepatic neuroendocrine carcinoma (PHNEC) manifests as a rare type of liver tumor. PHNEC is not specifically clinical or radiographical and often misdiagnosed mistreated. Here, we present case report in 50-year-old woman who was admitted to our department with concealed pain the right upper abdomen. The initial diagnosis probable space-occupying lesion tumor bleeding. patient subjected partial hemihepatectomy, cholecystectomy, resection lower lobe lung, diaphragm, perirenal fat sac...
Classical swine fever (CSF) is a highly contagious disease caused by the classical virus (CSFV), wreaking havoc on global production. The divided into three genotypes, each comprising 4-7 sub-genotypes. major envelope glycoprotein E2 of CSFV plays an essential role in cell attachment, eliciting immune responses, and vaccine development. In this study, to study cross-reaction cross-neutralizing activities antibodies against different genotypes (G) glycoproteins, ectodomains G1.1, G2.1, G2.1d,...
Hepatoid carcinoma of the pancreas (HCP) is an extremely rare pancreatic cancer resembling hepatocellular carcinoma, a type liver (1).Most reports have shown that it has aggressive behavior and associated with early
Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome characterized by fever, pancytopenia and splenomegaly. The underlying hemophagocytosis occurs primarily in the bone marrow, liver lymph nodes. Multiple microbiological agents, including cytomegalovirus, Epstein-Barr virus Mycobacterium tuberculosis, have been implicated pathogenesis of HLH. present study presents case HLH associated with Leuconostoc pseudomesenteroides infection treated successfully clindamycin. A...
To observe and determine the effect mechanism of psoralen on tumor necrosis factor-α (TNF-α)-induced muscle atrophy.Three sets C2C12 cells, including blank control, TNF-α (10 or 20 ng/ml) treatment a plus (80 μM) administration were investigated. Cell viability was assessed using Counting Kit-8 (CCK-8) assay. Western blot analysis used to detect protein expression atrophic markers. Flowcytometry apoptosis. A quantitative real-time PCR (qRT-PCR) assay performed mRNA level miR-675-5P.TNF-α (1,...
Papillomaviruses (PVs) usually cause benign proliferative lesions in the stratified epithelium of various animal species. However, some high-risk types PVs have been proven to lead malignant transformations. In dogs, several canine papillomaviruses (CPVs) identified and are suggested as one risk factors for development squamous cell carcinomas (SCCs). present study, full genomes two CPV9 strains from recurrent SCCs Dog 1 skin viral papilloma (viral plaque) 2 were sequenced. Alignment...
Propolis and its preparations are components of TCM functional food sources for antihyperlipidemia therapy. However, due to the metabolic properties propolis, individual remain ambiguous, especially those that therapeutically active. The study presented here identified primary target (PXR/CYP3A4) propolis activity against hyperlipidemia evaluated compounds select a quality control marker based on this activity. Mice fed high-fat diet were used efficacy followed by identification...
To compare the microstructural integrity of corticospinal tract (CST) between glioma patients with motor epilepsy and without using mean apparent propagator magnetic resonance imaging (MAP-MRI).A total 26 adjacent to CST pathway (10 16 epilepsy) 13 matched healthy controls underwent brain structural diffusion MRI. The morphological characteristics (tract volume, number, average length) were extracted, parameter values including squared displacement (MSD), q-space inverse variance (QIV),...
Mechanical ventilation (MV) is an important lifesaving method in intensive care unit (ICU). Prolonged MV associated with ventilator pneumonia (VAP) and other complications. However, premature weaning from may lead to higher risk of reintubation or mortality. Therefore, timely safe important. In addition, identification the right patient performing a suitable process necessary. Although several guidelines about have been reported, compliance these unknown. aim this study explore variation...