- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Congenital Heart Disease Studies
- Coronary Interventions and Diagnostics
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac Arrest and Resuscitation
- Transplantation: Methods and Outcomes
- Cardiac Health and Mental Health
- Coronary Artery Anomalies
- Parathyroid Disorders and Treatments
- Kawasaki Disease and Coronary Complications
- Central Venous Catheters and Hemodialysis
- Infectious Aortic and Vascular Conditions
- Intensive Care Unit Cognitive Disorders
- Pneumothorax, Barotrauma, Emphysema
- Muscle and Compartmental Disorders
- Head and Neck Anomalies
Onassis Cardiac Surgery Center
2015-2025
University of Rochester
2024
Academy of Athens
2020
St. Mary's Hospital
1997
Imperial College London
1997
Cardiac myxoma (CM) is the most common benign cardiac tumor. We retrospectively reviewed our single center experience in 153 patients with CM over a period 25 years. From November 1993 to May 2017, were operated institution diagnosis of CM. In all preoperative, perioperative, and postoperative data recorded including long-term follow-up. All followed up outpatient's clinics echocardiography at regular intervals. Mean age 59 ± 12 years old. There 104 women 49 men. Preoperative clinical...
Introduction: Myocardial inflammation often coexists with different types of autoimmune diseases. Our aim was to investigate the presence myocarditis in these patients by Cardiovascular Magnetic Resonance (CMR) and endomyocardial biopsy. Patients-Methods: Twenty patients, aged 20-55 yrs diseases cardiac symptoms (3 Takayasus arteritis, 3 systemic lupus erythematosus, 5 rheumatoid arthritis, 7 thyroid disease 2 sclerosis) 20 same but without (controls) were studied. The LV function evaluated...
Surgical aortic valve replacement has been the mainstay of treatment against severe insufficiency despite high incidence prosthesis-related complications and better long-term outcomes following repair. Annuloplasty leaflet reconstruction are integral parts procedure. Safety efficacy HAART internal annuloplasty ring hereby investigated through mid-term a single referral center. Forty-three consecutive patients with either trileaflet or bicuspid along ascending aorta and/or root enlargement...
Thrombocytopenia and thromboembolism(s) may develop in heparin immune-mediated thrombocytopenia (HIT) patients after reexposure to heparin. At the Onassis Cardiac Surgery Center, 530 out of 17,000 requiring heart surgery over an 11-year period underwent preoperative HIT assessment by ELISA a three-point heparin-induced platelet aggregation assay (HIPAG). The screening identified 110 with HIT-reactive antibodies, which 46 were also thrombocytopenic (true HIT). was performed HIT-positive under...
To elucidate the incidence, determinants, and consequences of severe sepsis after cardiac surgery.Prospective study.Cardiac surgical unit, Greece.2615 adult patients having operations.Microbiological evidence sepsis, mortality, duration stay in intensive care unit (ICU) hospital.Severe developed 41/2615 (2%), all during their ICU: there were 30 men 11 women, mean (SD) age 65 (10) years. It was most common combined coronary artery bypass grafting valve-related operations (7/95, 7%), followed...
We sought to define the predictive value and evolution of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels following transcutaneous aortic valve implantation (TAVI).We investigated 91 consecutive patients who underwent TAVI (59 transfemoral [TF], 32 transapical [TA]) in our institution. The balloon-expandable was implanted 75 self-expanding 16 patients. baseline (within 48 hours prior procedure), early (24-74 hours), late (3-12 months) postprocedural NT-proBNP were determined....
Aims and objectives To evaluate the one‐year prognosis of a lifestyle counselling intervention (diet, smoking cessation exercise) among patients who had open heart surgery. Background Cardiovascular disease is leading cause morbidity worldwide in both developing developed countries. Lifestyle modification plays an important role for are at high risk cardiovascular those with established disease. Design Randomised, nonblind study follow‐up. Methods A randomised, was performed on 500 After...
The aim of this study was to evaluate the gender-oriented differences in outcomes a lifestyle intervention trial (diet, smoking cessation, and exercise) among patients who had open heart surgery. A randomized, nonblind performed on 500 Immediately after hospital discharge, 250 were randomly allocated by receiving oral written information form booklet with specific educational for postoperative rehabilitation. remaining received regular instructions. applied proved be beneficial only men as...
Abstract: Off‐pump coronary artery bypass grafting (CABG) has been recently revived, because cardiopulmonary (CPB) appears to worsen the multiple organ dysfunction after conventional CABG. To evaluate safety and efficacy of off‐pump CABG in chronic dialysis patients, we compared perioperative morbidity mortality between 15 patients who underwent at our center over past 8 years with that a concurrent group 19 Patients were selected for only when complete revascularization was technically...
Cardiac surgery can lead to post-operative end-organ complications secondary activation of systemic inflammatory response. We hypothesize that surgical trauma or cardiopulmonary bypass (CPB) may initiate response via release mitochondrial DNA (mtDNA) signaling Toll-like receptor 9 (TLR9) and interleukin-6 production (IL-6).The role TLR9 in cardiac was studied using a murine model sternotomy porcine CPB. mtDNA IL-6 were measured with without TLR9-antagonist treatment. To study...
A 66-year-old man developed Aspergillus fumigatus endocarditis, complicated by an aortic root abscess 9 months after his valve replacement with a Carpentier Edwards xenograft. The was replaced antibiotic-treated fresh homograft and anti-fungal chemotherapy commenced 24 hours later. One month this he retrosternal pseudo-aneurysm of the ascending aorta. At re-operation heavily infected fungal growths patient considered inoperable. This case is example rare condition complicating cardiac...