Kamila Botelho Sampaio de Oliveira

ORCID: 0000-0003-4805-2224
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • Chemical Synthesis and Analysis
  • Protein Hydrolysis and Bioactive Peptides
  • Epigenetics and DNA Methylation
  • Transgenic Plants and Applications
  • Bacteriophages and microbial interactions
  • Toxin Mechanisms and Immunotoxins
  • Aquaculture disease management and microbiota
  • Electrospun Nanofibers in Biomedical Applications
  • Viral Infectious Diseases and Gene Expression in Insects
  • Biofuel production and bioconversion
  • Monoclonal and Polyclonal Antibodies Research
  • Microbial Metabolic Engineering and Bioproduction
  • Plant Parasitism and Resistance
  • Insect and Pesticide Research
  • Virus-based gene therapy research
  • Connective tissue disorders research
  • Enzyme Catalysis and Immobilization
  • Bee Products Chemical Analysis
  • RNA modifications and cancer
  • Machine Learning in Bioinformatics
  • Phytochemistry Medicinal Plant Applications
  • Genetics and Neurodevelopmental Disorders
  • Agricultural and Food Sciences

Universidade Católica Dom Bosco
2023-2025

Universidade Católica de Brasília
2016-2024

Universidade de Brasília
2020-2024

Molecular de-extinction has emerged as a novel strategy for studying biological molecules throughout evolutionary history. Among the myriad possibilities offered by ancient genomes and proteomes, antimicrobial peptides (AMPs) stand out particularly promising alternatives to traditional antibiotics. Various strategies, including software tools advanced deep learning models, have been used mine these host defense peptides. For example, computational analysis of disulfide bond patterns led...

10.15698/mic2025.02.841 article EN Microbial Cell 2025-01-01

Elastin-like polypeptides (ELPs) are biopolymers formed by amino acid sequences derived from tropoelastin. These biomolecules can be soluble below critical temperatures, forming aggregates at higher which makes them an interesting source for the design of different nanobiomaterials. nanobiomaterials obtained heterologous expression in several organisms such as bacteria, fungi, and plants. Thanks to many advantages ELPs, they have been used biomedical field develop nanoparticles, nanofibers,...

10.3389/fnano.2022.874790 article EN cc-by Frontiers in Nanotechnology 2022-04-25

Lactic acid (LA) production has seen significant progress over the past ten years. LA increased economic importance due to its broadening use in different sectors such as food, medicine, polymer, cosmetic, and pharmaceutical industries. bioprocesses using microorganisms are economically viable compared chemical synthesis can benefit from metabolic engineering for improved productivity, purity, yield. Strategies optimize productivity on strain improvement end include modifying routes, adding...

10.3390/jof10030207 article EN cc-by Journal of Fungi 2024-03-09

The constant demand for new antibiotic drugs has driven efforts by the scientific community to prospect peptides with a broad spectrum of action. In this context, antimicrobial (AMPs) have acquired great importance in recent years due their ability possess and immunomodulatory activity. last two decades, plants attracted interest industry as regards potential biofactories heterologous proteins. One most promising approaches is use viral vectors maximize transient expression leaves plant...

10.1590/0001-3765201820180124 article EN cc-by Anais da Academia Brasileira de Ciências 2018-10-19

Abstract The elucidation of the 3D structure DNA revolutionized modern science and created basis for field molecular biology. advent sequencing, further refinement with Next‐Generation Sequencing (NGS) techniques, has made possible enormous accumulation data, which are useful understanding mechanisms associated to various complex rare diseases. Thanks these advances, today it is known that several regulate gene expression without occurrence mutations in genome, a phenomenom as Epigenetics...

10.1002/adtp.201900184 article EN Advanced Therapeutics 2020-06-08

In article number 1900184 Nicolau Brito da Cunha, Fabricio F. Costa and co-workers review the current state of knowledge regarding three main epigenetic mechanisms gene regulation, which are DNA methylation, histone modification non-coding RNA expression. addition, therapies with “epidrugs” applied to precision medicine discussed. This is a field that receiving increased interest in scientific community industry.

10.1002/adtp.202070019 article EN Advanced Therapeutics 2020-08-01
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