A5009790868- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Acute Myocardial Infarction Research
- Cardiovascular Health and Risk Factors
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Innovations in Medical Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heparin-Induced Thrombocytopenia and Thrombosis
- Fatty Acid Research and Health
- Long-Term Effects of COVID-19
- Diet and metabolism studies
- Health, psychology, and well-being
- Medical Education and Admissions
- Craniofacial Disorders and Treatments
- Sleep and related disorders
- Global Public Health Policies and Epidemiology
- Problem and Project Based Learning
- Vaccine Coverage and Hesitancy
- Diabetes Management and Education
- vaccines and immunoinformatics approaches
- Pharmacological Effects and Assays
Hashemite University
2017-2024
The Farah Hospital
2014-2021
Oslo University Hospital
2019
Sykehuset i Vestfold
2019
University of Jordan
2019
COVID-19 (coronavirus disease 2019) vaccines induce immunity through different mechanisms. The aim of this study is to compare the titers specific antibodies in subjects vaccinated with either Pfizer-BioNTech vaccine or Sinopharm vaccine. This prospective observational cohort included Jordanian adults two doses, 21 days apart, aforementioned vaccines. Titers were collected 6 weeks after administration second dose. Overall, 288 participants included, which 141 administered vaccine, while 147...
Background . The Middle East is the home to most obese population in world, and type 2 diabetes mellitus endemic region. However, little known about risk factors for younger age groups. Methods Finnish Diabetes Risk Score (FINDRISC) a simple, validated tool identify persons at of diabetes. We investigated students Hashemite University Jordan with FINDRISC measured fasting plasma glucose those who were categorized high-risk group. Results Overall, 1821 (881 [48.4%] female) included study....
Vaccines are considered the best approach for countering COVID-19 pandemic. In this study, we compared early side effects associated with vaccination Sinopharm and Pfizer–BioNTech vaccines. Participants of observational cohort were interviewed based on semi-structured telephone interviews, enquiries about that developed after each dose these Overall, 1004 participants enrolled, which 51.1% received vaccine 48.9% vaccine. After first dose, 46.3% had an adverse reaction, injection site pain...
Background: Sharing bad news is a complex and challenging task for doctors, requiring knowledge skills development.Aims: To identify Jordanian doctors’ training needs breaking news, comparing two different populations of to investigate the applicability frameworks.Methods: This questionnaire based cross-sectional study targeted doctors working at hospitals in Amman, Jordan. Data was analyzed using SPSS v25 MedCalc v20. Comparisons were made chi-square test. Free text responses...
Unhealthy lifestyle factors such as smoking, obesity, inactivity and type 2 diabetes are endemic in the Middle East. The public health consequences might be detrimental; however, local studies on risk for coronary artery disease (CAD) scarce.Patients referred angiography at a tertiary hospital Amman, Jordan, between January December 2015, were included this study. Risk CAD assessed multivariate logistic regression model, presented odds ratio (OR) with 95% confidence interval (CI).Among 557...
Background: Although obesity is an independent risk factor for coronary artery disease (CAD), observational studies have found that persons with a better prognosis in established CAD compared those normal body weight, suggesting the underlying factors might differ between two groups. In this study, we studied and without Middle Eastern setting where endemic. Methods: Five hundred fifty-six patients referred elective catheterization at Prince Hamza Hospital, Amman were included...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung infection has represented a global challenge. Intriguingly, it been shown that the alveolar epithelium expresses little Angiotensin Converting Enzyme receptor protein (ACE2), entry for SARS-CoV-2. Upper airway establishment of and translocation to is well documented but other anatomical niches may be relevant potentially serious infection. ACE2 heavily expressed in gastrointestinal tract symptoms support clinical diagnosis...
Fruit and vegetable intake has been reported as one of the significant protective factors against development cardiovascular diseases (CVD). This study aimed to assess possible preventive effect fruit consumption on developing CVD.A total 398 participants (205 cases 193 controls) referred for elective coronary angiography with clinical suspicion artery disease Prince Hamza Hospital in Amman were enrolled this case-control study. Dietary data collected separately from each patient using...
The long-term immunoglobulin responses of COVID-19 vaccinations is important to determine the efficacy these vaccinations. This study aimed investigate and compare response vaccination recipients, using anti-S IgG, anti-N IgM titer levels. included 267 participants, comprising individuals who tested positive for through PCR testing (n = 125), those received Pfizer 133), Sinopharm 112), AstraZeneca 20), or Sputnik 2) vaccines. Female participants comprised largest share this 147, 55.1%)....
BACKGROUND/AIM: The newly described proteins adropin and irisin are a highly conserved polypeptide that plays essential roles in metabolic energy homeostasis, insulin resistance, fat browning. aim of this study is to evaluate the circulating levels serum type 2 diabetes mellitus (T2DM) patients also elucidate possible relationships between with anthropometric obesity indices biochemical parameters. SUBJECTS AND METHODS: Single-center prospective observational included 90 T2DM referred...
Accumulating evidence suggests that consumption of whole grains and legumes is associated with reduced risk cardiovascular disease (CVD), whereas the increased by consuming refined cereals. This study aimed to investigate association between grain legume CVD. The was conducted using a convenient sampling method total 399 participants who underwent coronary angiography. Cases controls were matched age 1:1 ratio. Standardized validated questionnaires used collect socio- demographic, health,...
Background and Objectives: Although physical health is always studied for women with diabetes, the mental aspect generally overlooked this chronic disease. The present study aimed to examine prevalence of psychosomatic symptoms, namely, fibromyalgia syndrome, depression, anxiety, insomnia, how these symptoms related medications used in a cohort diagnosed type 2 diabetes (DM) Jordan. Materials Methods: This cross-sectional recruited validated scales (PSRS, PHQ-9, GAD-7, ISI-A) insomnia were...
Major depressive disorder is prevalent across different societies, affecting individuals from various cultural and socioeconomic backgrounds. Dysregulation of the nitric oxide (NO) pathway increased oxidative stress have been implicated as contributing factors. This study aimed to explore antidepressant potential β-caryophyllene in a mouse model subjected maternal separation stress, with focus on its effects nitrite levels. The research involved 40 male mice, which were divided into five...
This study examined whether antihypertensive medications and other patient characteristics are associated with severe depressive symptoms in patients hypertension.Patients a diagnosis of hypertension were recruited from the internal medicine outpatient clinics hospital Amman, Jordan, into this cross-sectional study. Depression severity was assessed using Patient Health Questionnaire-9 (PHQ-9); anxiety by General Anxiety Disorder-7; sleep quality Insomnia Severity Index; psychological stress...
A variant of SARS-CoV-2 from Jordan was identified during the second wave infection. The genome this has a unique set mutations that suggest local evolution. Due to continuous emergence new variants worldwide, molecular surveillance is crucial for fighting pandemic.
This hospital-based study aimed to evaluate the nutritional status and dietary habits, amount of nutrients provided patients in hospital detect predictors severity among COVID-19 Jordan.A (N = 367; mean age 42.3 y; SD 15.4; 66.0% men) was conducted between March 17 July 25, 2020, Prince Hamza Hospital. Data about socio-demographic, anthropometric, macro- micronutrients intake were collected from patients' medical files, some missing data by phone directly patients.The results linear...
Objective: To analyse the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in a Jordanian subgroup 24-week, non-interventional A1chieve study. Methods: A total 509 patients with type 2 diabetes (392 insulin-naive 117 insulin-experienced) starting BIAsp30, alone or combination oral glucose-lowering drugs, were included. Safety outcomes analysed over 24 weeks. Results: Patients had mean age 55.8 years, body mass index 28.8 kg/m2 duration 9.4 years at baseline. Two serious...
Obesity and its metabolic complications are endemic in the Middle East, but cardiovascular consequences not well defined local studies.To assess association between fasting blood glucose (FBG), obesity coronary artery disease (CAD) Jordan.A cross-sectional, hospital-based study.A referral hospital Amman, Jordan.Patients with complete anthropomorphic data who were referred for elective angiography included analysis. Associations CAD, FBG assessed multivariate logistic regression models,...
This study aimed to determine whether the intake of antioxidants was a risk factor for developing coronary artery disease. A total 399 participants who underwent angiography were included in study, and patients with disease (cases) compared normal (controls). Antioxidant consumption higher control group than cases. Specifically, controls had foods rich lutein, zeaxanthin, β-carotene, lycopene, but difference did not reach statistical significance. The findings suggest possible beneficial...
Sulfotransferases (SULTs) family plays a significant role in the biotransformation of variety xenobiotics and endogenous compounds by which carcinogenesis mutagenicity different malignancies are increasingly affected. Recent data identified various genetically polymorphic SULTs enzymes with variations enzyme activity. This study aimed to investigate impact SULT1A1 gene polymorphism its potential risk on females breast cancer Jordan using PCR-RFLP Sanger Sequencing methods. The analysis...