- RNA Interference and Gene Delivery
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- Advanced biosensing and bioanalysis techniques
- Bacterial Genetics and Biotechnology
- Nanoparticle-Based Drug Delivery
- DNA and Nucleic Acid Chemistry
- Nanoplatforms for cancer theranostics
University of Copenhagen
2024
Shanghai Jiao Tong University
2023
Tianjin University
2023
Abstract Heterogeneity and drug resistance of tumor cells are the leading causes incurability poor survival for patients with recurrent breast cancer. In order to accurately deliver biological anticancer drugs different subtypes malignant omnidirectional targeted treatment cancer, a distinct design is demonstrated by embedding liposome‐based nanocomplexes containing pro‐apoptotic peptide survivin siRNA (LPR) into Herceptin/hyaluronic acid cross‐linked nanohydrogels (Herceptin‐HA) fabricate...
Strict on-demand control of protein synthesis is a crucial aspect synthetic biology. The 5′-terminal untranslated region (5′-UTR) an essential bacterial genetic element that can be designed for the regulation translation initiation. However, there insufficient systematical data on consistency 5′-UTR function among various cells and in vitro systems, which standardization modularization elements Here, more than 400 expression cassettes comprising GFP gene under 5′-UTRs were systematically...