- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Adaptive optics and wavefront sensing
- Advanced X-ray and CT Imaging
- Medical Imaging and Analysis
- Astronomy and Astrophysical Research
- Stellar, planetary, and galactic studies
- Breast Cancer Treatment Studies
- MRI in cancer diagnosis
- Lung Cancer Diagnosis and Treatment
- Optical Systems and Laser Technology
- Radiation Detection and Scintillator Technologies
- Solar and Space Plasma Dynamics
- Credit Risk and Financial Regulations
- Ultrasound and Hyperthermia Applications
- Advanced MRI Techniques and Applications
- Nonmelanoma Skin Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Digital Radiography and Breast Imaging
- Cerebrovascular and Carotid Artery Diseases
- Meningioma and schwannoma management
- Banking stability, regulation, efficiency
Yonsei University
2013-2025
Kangnam University
2022-2025
Gangnam Severance Hospital
2022-2024
Korea Astronomy and Space Science Institute
2014-2024
Chungbuk National University
2005-2024
Catholic University of Korea
2008-2023
Seoul St. Mary's Hospital
2016-2023
Seoul National University Hospital
2008-2022
Sungkyunkwan University
2022
Samsung (South Korea)
2006-2022
Abstract Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro model to recapitulate brain development and neurological diseases. However, the current systems for organoid culture require further improvement reliable production of high-quality organoids. Here, we demonstrate two engineering elements improve culture, (1) extracellular matrix brain-specific cues (2) microfluidic device with periodic flow survival reduce variability A three-dimensional...
Background: One of the perceived major drawbacks minimally invasive techniques has always been its cost. This is especially true for robotic approach and one main reasons that prevented wider acceptance among hospitals surgeons. The aim our study was to evaluate clinical outcomes economic impact open liver surgery in a single institution. Methods: Sixty-eight 55 hepatectomies were performed at institution between January 1, 2009 December 31, 2013. Demographics, perioperative data,...
Importance Atrial fibrillation (AF) can develop following thoracic irradiation. However, the critical cardiac substructure responsible for AF has not been properly studied. Objective To describe incidence of in patients with lung cancer and determine predictive dosimetric parameters. Design, Setting, Participants This retrospective cohort study was performed at a single referral center included 239 diagnosed limited-stage small cell (SCLC) 321 locally advanced non–small (NSCLC) between...
An image enhancement algorithm for low-vision patients was developed images compressed using the JPEG standard. The proposed enhances in discrete cosine transform domain by weighting quantization table decoder. Our specific implementation increases contrast at all bands of frequencies an equal factor. has four advantages: 1) low computational cost; 2) suitability real-time application; 3) ease adjustment end-users (for example, adjusting a single parameter); and 4) less severe block...
To develop an online plan adaptation algorithm for intensity modulated proton therapy (IMPT) based on fast Monte Carlo dose calculation and cone beam CT (CBCT) imaging.
The GMT-Consortium Large Earth Finder (G-CLEF) will be a cross-dispersed, optical band echelle spectrograph to delivered as the first light scientific instrument for Giant Magellan Telescope (GMT) in 2022. G-CLEF is vacuum enclosed and fiber-fed enable precision radial velocity (PRV) measurements, especially detection characterization of low-mass exoplanets orbiting solar-type stars. passband broad, extending from 3500Å 9500Å. This provides good sensitivity at blue wavelengths stellar...
This study examines the informational value and timeliness of credit ratings by analyzing default swap (CDS) spreads around events. Using a novel "new percentile test" framework, we investigate credibility promptness rating adjustments within given category. Our findings reveal that CDS significantly increase before downgrades, indicating lack diminished these ratings. results support hypothesis agencies are conservative when releasing revealing bias favoring issuers. Furthermore, relative...
We present a 3-5um LBT/MMT adaptive optics imaging study of three Upper Scorpius stars with brown dwarf (BD) companions very low-masses/mass ratios (M_BD < 25M_Jup; M_BD / M_star ~ 1-2%), and wide separations (300-700 AU): GSC 06214, 1RXS 1609, HIP 78530. combine these new thermal IR data existing 1-4um 24um photometry to constrain the properties BDs identify evidence for circumprimary/secondary disks in unusual systems. confirm that 06214B is surrounded by disk, further showing this disk...
To retrospectively compare the therapeutic effects of combined high-intensity focused ultrasound (HIFU) and transarterial chemoembolisation (TACE) with TACE alone for treatment non-advanced hepatocellular carcinomas (HCCs) <5 cm.We reviewed tumour responses 32 HCCs 25 patients who underwent HIFU TACE, 46 only. The mean follow-up observation TACE+HIFU group was on average 31 months that 33 months. Those had undergone any other modality (including systemic chemotherapy) during period were...
Objective. To develop a 3D shear wave elastography (SWE) technique using 2D row column addressing (RCA) array, with either external vibration or acoustic radiation force (ARF) as the source. Impact Statement. The proposed method paves way for clinical translation of SWE based on RCA, providing low-cost and high volume rate solution that is compatible existing systems. Introduction. an established ultrasound imaging modality provides direct quantitative assessment tissue stiffness, which...
We report on a successful fabrication of silicon-based single-electron transistors (SETs) with low RC time constant and their applications to complementary logic cells SET/field-effect transistor (FET) hybrid integrated circuit. The SETs were fabricated silicon-on-insulator (SOI) structure by pattern-dependent oxidation (PADOX) technique, combined e-beam lithography. Drain conductances measured at 4.2 K approach large values the order microsiemens, exhibiting Coulomb oscillations...
The Large Binocular Telescope Interferometer, a thermal infrared imager and nulling interferometer for the LBT, is currently being integrated tested at Steward Observatory. system consists of general purpose or universal beamcombiner (UBC) three camera ports, one which populated by Nulling Imaging Camera (NIC). Wavefront sensing carried out using pyramid-based "W" units developed Arcetri designed high spatial resolution, dynamic range imaging in infrared. A key project program to survey...
Proton therapy has dosimetric advantages due to the well-defined range of proton beam over photon radiotherapy. When beams, however, are delivered patient in fractionated radiation treatment, treatment outcome is affected by delivery uncertainties such as anatomic change and daily setup error. This study aims at establishing a method evaluate impact error during head neck therapy. Range variations were assessed calculating water equivalent path length (WEPL) distal edge tumor volume using...
In breast cancer radiation therapy, minimizing radiation-related risks and toxicity is vital for improving life expectancy. Tailoring radiotherapy techniques treatment positions can reduce doses to normal organs mitigate treatment-related toxicity. This study entailed a dosimetric comparison of six different external beam whole-breast irradiation in both supine prone positions. We selected fourteen patients, generating plans per patient. assessed target coverage at risk (OAR) evaluate the...
A 1.5-V 512-Mb DDR3 synchronous DRAM prototype was designed and fabricated in 80-nm technology. Critical to the signal integrity point-to-2points (P22P) interfacing is an efficient calibration scheme C/sub IO/ minimization, which were achieved by on-die-termination (ODT)-merged output drivers, SCR type ESD protection, self-calibration scheme. The hybrid latency control can turn DLL off standby mode, reducing power consumption. User-friendly functions such as temperature read-out from on-chip...
Glucose/O2 biofuel cells (BFCs) with an improved power density and stability were developed, using glucose oxidase (GOD) nanotubes polypyrrole (PPy)–carbon (CNTs)–GOD layers deposited on their surface as anode a PPy–laccase–2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonate) diammonium salt (ABTS) film type cathode. The GOD fabricated within the nanopores of anodized aluminum oxide membrane template-assisted layer-by-layer deposition method. These BFCs exhibited higher volumetric than best...