Sarah Melville

ORCID: 0000-0003-4867-3979
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About
Contact & Profiles
Research Areas
  • Blood Pressure and Hypertension Studies
  • Pelvic floor disorders treatments
  • Hemodynamic Monitoring and Therapy
  • Telemedicine and Telehealth Implementation
  • Diet and metabolism studies
  • Cardiac Health and Mental Health
  • Cardiovascular Health and Disease Prevention
  • Non-Invasive Vital Sign Monitoring
  • Heart Rate Variability and Autonomic Control
  • Nonprofit Sector and Volunteering
  • Peroxisome Proliferator-Activated Receptors
  • Cardiac Ischemia and Reperfusion
  • Organ and Tissue Transplantation Research
  • Inflammatory mediators and NSAID effects
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Disease and Adiposity
  • Urinary Tract Infections Management
  • COVID-19 and healthcare impacts
  • Fatty Acid Research and Health
  • Mobile Health and mHealth Applications
  • Hormonal Regulation and Hypertension
  • Prenatal Screening and Diagnostics
  • Bone fractures and treatments
  • Nutrition and Health in Aging
  • Sport and Mega-Event Impacts

Saint John Regional Hospital
2014-2022

Dalhousie University
2019-2021

University of Southern California
2021

Horizon Health Network
2020-2021

University of Northampton
2019

Charles River Laboratories (United Kingdom)
2010

Lawson Health Research Institute
2006

University of Aberdeen
1989

Chinese University of Hong Kong
1988

During the COVID-19 pandemic, telemedicine has emerged worldwide as an indispensable resource to improve surveillance of patients, curb spread disease, facilitate timely identification and management ill people, but, most importantly, guarantee continuity care frail patients with multiple chronic diseases. Although during thrived, its adoption moved forward in many countries, important gaps still remain. Major issues be addressed enable large scale implementation include: (1) establishing...

10.20517/ch.2021.03 article EN Connected Health 2022-01-01

This Clinical Update summarizes the main approaches to out-of-office blood pressure monitoring—home monitoring and ambulatory benefits challenges of each in management hypertension.

10.1001/jama.2018.14865 article EN JAMA 2018-11-06

Background: Clinical guidelines recommend monitoring of blood pressure at home using an automatic device for the management hypertension. Devices are not often calibrated against direct measures, leaving health care providers and patients with less reliable information than is possible current technology. Rigorous assessments medical devices necessary establishing clinical utility. Objective: The purpose our study was 2-fold: (1) to assess validity perform iterative calibration indirect...

10.2196/jmir.8009 article EN cc-by Journal of Medical Internet Research 2018-04-25

Introduction Increasing levels of obesity worldwide have led to a rise in the prevalence obesity-related complications including cardiovascular risk factors such as diabetes, hypertension and dyslipidaemia. Healthcare providers believe that overweight obese cardiac surgery patients are more likely experience adverse postoperative outcomes. The body mass index (BMI) is primary measure clinical practice, without accounting for patient’s level cardiopulmonary fitness or muscle mass. objective...

10.1136/bmjopen-2018-023418 article EN cc-by-nc BMJ Open 2019-03-01

Monitoring Blood Pressure Outside of the Doctor's OfficeIf your blood pressure is suspected to be high, it important know measurement pattern outside doctor's office.

10.1001/jama.2018.11644 article EN JAMA 2018-11-06

Abstract Canada is a wealthy nation with geographically diverse population, seeking health innovations to better serve patients in accordance the Health Act. In this country, population and geography converge social determinants, policy, procurement regulations, technological advances, order achieve equity management distribution of healthcare. Rural remote are vulnerable population; when managing chronic conditions such as cardiovascular disease, there inequity it comes accessing specialist...

10.1101/2020.12.17.20248333 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-12-19

Over the past year, amyotrophic lateral sclerosis (ALS) associations have benefitted from people embracing “ice bucket challenge,” in which cold water is tipped over participant’s head. To date, about 150 million dollars has been donated worldwide as a result of challenge. However

10.1503/cmaj.141241 article EN cc-by-nc-nd Canadian Medical Association Journal 2014-12-08

It is generally accepted that induction of iNOS, but not eNOS, in the heart renders it less susceptible to detrimental effects an ischemia/reperfusion (I/R) challenge. However, there some evidence indicate eNOS (adenosine receptor agonist) can also provide protection against I/R-induced myocardial dysfunction and injury. We have recently shown pretreatment with erythropoietin (EPO) ameliorate inflammation associated I/R challenge given 24 hrs later. The aim present study was determine...

10.1096/fasebj.20.5.a1153 article EN The FASEB Journal 2006-03-01
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