A5062785832- Ionosphere and magnetosphere dynamics
- GNSS positioning and interference
- Solar and Space Plasma Dynamics
- Earthquake Detection and Analysis
- Geophysics and Gravity Measurements
- Geomagnetism and Paleomagnetism Studies
- Space exploration and regulation
- Astro and Planetary Science
- Atmospheric Ozone and Climate
- International Development and Aid
- Photosynthetic Processes and Mechanisms
- Cancer Immunotherapy and Biomarkers
- Spectroscopy and Quantum Chemical Studies
- Lung Cancer Treatments and Mutations
- Space Exploration and Technology
- Eating Disorders and Behaviors
- Oceanographic and Atmospheric Processes
- Colorectal Cancer Treatments and Studies
- Cancer Genomics and Diagnostics
- Space Satellite Systems and Control
- Pain Management and Placebo Effect
- Spacecraft Design and Technology
- Acupuncture Treatment Research Studies
- Planetary Science and Exploration
- Tropical and Extratropical Cyclones Research
RMIT University
2016-2025
The University of Texas MD Anderson Cancer Center
2018-2025
MIT University
2015-2025
The Royal Melbourne Hospital
2012-2024
University of New Hampshire
2023-2024
Los Alamos National Laboratory
2024
Space Science Institute
2024
Astronomy and Space
2023
ACT Government
2023
RMIT Europe
2023
Abstract Global Navigation Satellite System (GNSS)‐based radio occultation (RO) is a satellite remote sensing technique providing accurate profiles of the Earth's atmosphere for weather and climate applications. Above about 30 km altitude, however, statistical optimization critical process initializing RO bending angles in order to optimize monitoring utility retrieved atmospheric profiles. Here we introduce an advanced dynamic algorithm, which uses from multiple days European Centre...
The assumption that drug repurposing efficiently delivers new drugs ignores the realities of development required to achieve regulatory approval.
Abstract Geomagnetically induced currents (GICs) caused by interplanetary shocks represent a serious space weather threat to modern technological infrastructure. The arrival of drives magnetosphere and ionosphere current systems, which then induce electric at ground level. impact these high latitudes has been extensively researched, but the magnetic equator largely overlooked. In this paper, we investigate potential effects on equatorial region demonstrate that their signature is amplified...
Abstract An analysis of the occurrence equatorial plasma bubbles (EPBs) around world during 2015 St. Patrick's Day geomagnetic storm is presented. A network 12 Global Positioning System receivers spanning from South America to Southeast Asia was used, in addition colocated VHF at three stations and four nearby ionosondes. The suppression postsunset EPBs observed across most longitudes over 2 days. EPB observations were compared calculations linear Rayleigh‐Taylor growth rate using coupled...
Abstract We report our analysis of ionospheric disturbances from the 15 January 2022 Tonga volcano eruption, using GPS data International GNSS Service network and ionosonde in Australian sector. Wave fluctuations with amplitudes ∼1 TECU altitude variations ∼100 km were observed data, respectively. In near‐field region around shortly after reveals that had an azimuthally anisotropic velocity profile, a peculiar minimum southwestward direction. Close resemblance is identified between profile...
For patients with advanced non-small-cell lung cancer (NSCLC), dual immune checkpoint blockade (ICB) CTLA4 inhibitors and PD-1 or PD-L1 (hereafter, PD-(L)1 inhibitors) is associated higher rates of anti-tumour activity immune-related toxicities, when compared treatment alone. However, there are currently no validated biomarkers to identify which will benefit from ICB1,2. Here we show that NSCLC who have mutations in the STK11 and/or KEAP1 tumour suppressor genes derived clinical ICB...
Abstract The technique of radio occultation (RO) is demonstrated to be a powerful tool for studying equatorial F‐region irregularities (EFIs) associated with plasma bubbles. extensive 4.9 year RO dataset the Constellation Observing System Meteorology, Ionosphere and Climate (COSMIC) satellites was employed in this study contains EFI observations under wide variety solar geomagnetic conditions. From an analysis occurrence dependence on season/longitude, it found that statistics largely match...
Abstract Presented is an analysis of the occurrence postsunset Equatorial Plasma Bubbles (EPBs) detected using a Global Positioning System (GPS) receiver at Vanimo. The three year data set shows that EPB maximizes (minimizes) during equinoxes (solstices), in good agreement with previous findings. Vanimo ionosonde station used GPS day‐to‐day variability 2000 equinox period. A superposed epoch (SEA) reveals altitude, and change F layer height ∼1 standard deviation (1 σ ) larger on days for...
Abstract The occurrence of geomagnetically induced currents (GICs) poses serious threats to modern technological infrastructure. Large GICs result from sharp variations the geomagnetic field (d B /d t ) caused by changes large‐scale magnetospheric and ionospheric currents. Intense d perturbations are known occur often in high‐latitude regions as a storm time substorms. Magnetospheric compressions usually interplanetary shocks increase magnetopause current leading more evident midlatitude...
Abstract Geomagnetically induced currents (GICs) represent a significant space weather issue for power grid and pipeline infrastructure, particularly during severe geomagnetic storms. In this study, magnetometer data collected from around the world are analyzed to investigate GICs caused by 2015 St. Patrick's Day storm. While GIC activity in high‐latitude regions due storm time substorm is shown event, enhanced was also measured at two equatorial stations American Southeast Asian sectors....
Abstract Describing the day‐to‐day variability of Equatorial Plasma Bubble (EPB) occurrence remains a significant challenge. In this study we use Thermosphere‐Ionosphere Electrodynamics General Circulation Model (TIEGCM), driven by solar ( F 10.7 ) and geomagnetic K p activity indices, to daily variations linear Rayleigh‐Taylor (R‐T) instability growth rate in relation measured scintillation strength at five longitudinally distributed stations. For locations characterized generally favorable...
Abstract We present the results of our GPS total electron content and ionosonde observations large‐scale traveling ionospheric disturbances (LSTIDs) during 26 September 2011 geomagnetic storm. analyzed propagation characteristics these LSTIDs from auroral zones all way to equatorial region studied how opposite hemispheres interact/interfere near equator. found an overall speed ∼700 m/s for that resultant amplitude LSTID interference pattern actually far exceeded sum individual amplitudes...
In this study, a comprehensive investigation into the inter-relationships among twelve atmospheric variables and their responses to precipitation was conducted. These include two Global Navigation Satellite Systems (GNSS) tropospheric products, eight weather time-varying parameters. Their observations corresponding record over period 2008–2019 were obtained from pair of GNSS/weather stations in Hong Kong. Firstly, based on correlation regression analyses, cross-relationships systematically...
Glembatumumab vedotin (CDX-011, GV) is a fully human Immunoglobulin G2 monoclonal antibody directed against glycoprotein NMB coupled via peptide linker to monomethyl auristatin E (MMAE), potent cytotoxic microtubule inhibitor. This phase II study evaluated the overall response rate and safety of GV, (GPNMB) expression, survival in patients with metastatic uveal melanoma. Eligible melanoma who had not previously been treated chemotherapy received GV 1.9 mg/kg every three weeks. The primary...
Abstract Predicting the daily variability of Equatorial Plasma Bubbles (EPBs) is an ongoing scientific challenge. Various methods for predicting EPBs have been developed, however, research community yet to scrutinize evaluating and comparing these prediction models/techniques. In this study, 12 months co‐located GPS UHF scintillation observations spanning South America, Atlantic/Western Africa, Southeast Asia, Pacific sectors are used evaluate Generalized Rayleigh‐Taylor (R‐T) growth rates...
Centimetre-level accurate ionospheric corrections are required for a high accuracy and rapid convergence of Precise Point Positioning (PPP) GNSS positioning solutions. This research aims to evaluate the local/regional delay model using linear interpolation method across Australia. The is assessed as function both different latitudinal regions number spatial density Continuously Operating Reference Stations (CORSs). Our shows that, local region 5° latitude ×10° longitude in mid-latitude...
Abstract The Hunga Tonga Volcano eruption launched a myriad of atmospheric waves that have been observed to travel around the world several times. These generated traveling ionospheric disturbances (TIDs) in ionosphere, which are known adversely impact radio applications such as Global Navigation Satellite Systems (GNSS). One GNSS application is Precise Point Positioning (PPP), can achieve cm‐level accuracy using single receiver, following typical convergence time 30 min 1 hr. A network...