A5079860166- COVID-19 epidemiological studies
- Cervical Cancer and HPV Research
- Genital Health and Disease
- Hepatitis B Virus Studies
- Vector-Borne Animal Diseases
- Viral Infections and Outbreaks Research
- Animal Behavior and Reproduction
- Molecular Biology Techniques and Applications
- Plant and animal studies
- SARS-CoV-2 and COVID-19 Research
- Evolution and Genetic Dynamics
- Genetic factors in colorectal cancer
- Mathematical and Theoretical Epidemiology and Ecology Models
- Reproductive tract infections research
- Noise Effects and Management
- Health, Medicine and Society
- Indoor Air Quality and Microbial Exposure
- Air Quality and Health Impacts
Université de Montpellier
2020-2025
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2020-2025
Centre National de la Recherche Scientifique
2021-2025
Institut de Recherche pour le Développement
2020-2025
Agropolis International
2021
Inserm
2019
Sorbonne Université
2019
Centre de Recherche Saint-Antoine
2019
Université Paris Cité
2018
Délégation Paris 5
2018
Human papillomavirus (HPV) infections drive one in 20 new cancer cases, exerting a particularly high burden on women. Most anogenital HPV are cleared less than two years, but the underlying mechanisms that favour persistence around 10% of women remain largely unknown. Notwithstanding, it is precisely this information crucial for improving treatment, screening, and vaccination strategies. To understand viral immune dynamics non-persisting infections, we set up an observational longitudinal...
Background We studied the duration of HPV detection and risk (re-) for 25 genotypes in a cohort 132 women followed every eight weeks up to two years between 2016 2020. Participants were 18 old at inclusion half them vaccinated against HPV. They recruited near University STI centre Montpellier, France.
AbstractDisassortative mating is a rare form of mate preference that promotes the persistence polymorphism. While evolution assortative and its consequences for trait variation speciation have been extensively studied, conditions enabling disassortative are still poorly understood. Mate preferences increase risk missing opportunities, cost can be compensated by greater fitness offspring. Heterozygote advantage should therefore promote mating, which maximizes number heterozygous From analysis...
Estimating the date at which an epidemic started in a country and it can end depending on interventions intensity are important to guide public health responses. Both potentially shaped by similar factors including stochasticity (due small population sizes), superspreading events, memory effects (the fact that occurrence of some e.g. recovering from infection, depend past, number days since infection). Focusing COVID-19 epidemics, we develop analyse mathematical models explore how these...
Abstract Estimating the date at which an epidemic started in a country and it can end depending on interventions intensity are important to guide public health responses. Both potentially shaped by similar factors including stochasticity (due small population sizes), superspreading events, ‘memory effects’ (the fact that occurrence of some e.g. recovering from infection, depend past, number days since infection). Focusing COVID-19 epidemics, we develop analyse mathematical models explore how...
Human papillomavirus (HPV) infections drive one in twenty new cancer cases. Despite the potential for improving treatment, screening, and vaccination strategies, little is known as to why most HPV clear spontaneously within two years. To untangle dynamics of these non-persisting infections, we performed a combined quantitative analysis virological, immunological, clinical data from an original longitudinal cohort 189 women with high temporal resolution. We find that viral load reaches...
Human Papillomaviruses (HPV) are one of the most prevalent sexually transmitted infections (STI) and oncogenic viruses known to humans. The vast majority HPV clear in less than 3 years, but underlying mechanisms, especially involvement immune response, still poorly known. Building on earlier work stressing importance randomness type cell divisions clearance infection, we develop a stochastic mathematical model dynamics that combines previous aspect with an explicit description intracellular...
Abstract Objectives HPV infections are ubiquitous. For most infections, we lose track of the presence virus in host less than three years after start infection. The mechanisms regulating persistence infection still partially understood. In this work, focus on incident detection young women and characterise dynamics these evaluate effect genotype socio-economic factors duration time between detection. Methods We investigated human papillomavirus (HPV) patterns 182 Montpellier, France. relied...
Abstract Disassortative mating is a rare form of mate preference that promotes the persistence polymorphism. While evolution assortative mating, and its consequences on trait variation speciation have been extensively studied, conditions enabling disassortative are still poorly understood. Mate preferences increase risk missing opportunities, cost can be compensated by greater fitness offspring. Heterozygote advantage should therefore promote which maximizes number heterozygous From analysis...