A5083784720- Disaster Response and Management
- Hepatitis B Virus Studies
- Viral Infections and Outbreaks Research
- Reproductive tract infections research
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Zoonotic diseases and public health
- Aquaculture disease management and microbiota
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Machine Learning in Healthcare
- Antimicrobial Resistance in Staphylococcus
- COVID-19 diagnosis using AI
- Aquaculture Nutrition and Growth
- Salmonella and Campylobacter epidemiology
- Syphilis Diagnosis and Treatment
- Invertebrate Immune Response Mechanisms
- Blood donation and transfusion practices
- Neonatal and Maternal Infections
- Animal Disease Management and Epidemiology
- Animal Genetics and Reproduction
- Vaccine Coverage and Hesitancy
- Ethics in Clinical Research
- Pediatric health and respiratory diseases
- Acne and Rosacea Treatments and Effects
Australian National University
2008-2023
World Health Organization - Lyon Office
2020
World Health Organization
2018
Hunter New England Local Health District
2018
National Centre for Immunisation Research & Surveillance
2018
Australian Government
2010
James Cook University
1994-2010
Department of Health and Aged Care
2010
Government of the Northern Territory
2008-2009
Background Trachoma is the leading infectious cause of blindness due to conjunctival infection with Chlamydia trachomatis. The presence active trachoma and evidence are poorly correlated a strong immunologically-mediated inflammatory response means that clinical signs last much longer than infection. This population-based study in five Aboriginal communities endemic for northern Australia compared fine grading diagnostic positivity organism load. Methods A consensus trachoma, based on...
We estimated the potential benefits of advancing first dose pertussis vaccine for infants from 8 to 6 weeks age, using Australian national disease databases. Infants had notification rates 3-fold greater than general population and accounted 52% recorded hospitalizations. 1 2 months age 3.5 times (95% CI: 2.7-4.5) higher 3 11 age. Estimation acceleration reduced average notifications, hospitalizations, hospital bed-days by 8%, 9%, 12%, respectively, with larger reductions in an epidemic year.
Abstract Access to Hepatitis B Virus (HBV) testing for people in low-resource settings has long been challenging due the gold standard, enzyme immunoassay, being prohibitively expensive, and requiring specialised skills facilities that are not readily available, particularly remote isolated laboratories. Routine pathology data tandem with cutting-edge machine learning shows promising diagnostic potential. In this study, recursive partitioning (“trees”) Support Vector Machines (SVMs) were...
Objective To assess the performance of an early warning, alert and response system (EWARS) developed by World Health Organization (WHO) -EWARS in a Box -that was used to detect control disease outbreaks after Cyclone Winston caused destruction Fiji on 20 February 2016.Methods Immediately cyclone, Fiji's Ministry Medical Services, supported WHO, started implement EWARS Box, which is smartphone-based, automated, warning surveillance for rapid deployment during health emergencies.Both...
We investigated the risk factors and origins of first known occurrence VRE colonization in neonatal intensive care unit (NICU) at Canberra Hospital.A retrospective case-control study.A 21-bed a 15-bed special nursey (SCN) tertiary-care adult pediatric hospital Australia.All patients admitted to NICU SCN over outbreak period: January-May 2017. Of these, 14 were colonized with vancomycin-resistant Enterococcus (VRE) 77 noncolonized.Demographic clinical variables cases controls compared...
<h3>Aims:</h3> The aim of the study was to determine rates trachoma in Aboriginal communities and compare clinical assessment with photographic for presence signs trachoma. <h3>Methods:</h3> Five Katherine region Northern Territory, Australia, were assessed Trachoma diagnosed by eye examination using a fine grading based on World Health Organization (WHO) simplified system. Photographs taken left every person graded compared each <h3>Results:</h3> A total 1316 people out 1545 (85.2%)...
This paper discusses the contributions that One Health principles can make in improving global response to zoonotic infectious disease. We highlight some key benefits of taking a approach range complex disease problems have defied more traditional sectoral approach, as well public health policy and practice, where gaps surveillance systems need be addressed. The historical examples demonstrate scope Health, partly from an Australian perspective, but also with international flavour,...
The Ebola outbreak in 2014 marked the first time that an epidemic of this viral haemorrhagic fever had occurred West Africa. From its origin Guinea, rapidly increased to become a humanitarian crisis affecting all aspects life three countries worst affected: Sierra Leone and Liberia. Improving understanding virus disease among general population instigating behavioural changes required help break were central public health response. This article explores some misconceptions about as it spread...
BackgroundBetween December 2013 and June 2016, West Africa experienced the largest Ebola virus disease (EVD) outbreak in history. Understanding EVD pregnancy is important for clinical screening infection prevention control.MethodsWe conducted a review of medical records investigation reports from three districts Sierra Leone. We report presentations maternal fetal outcomes six pregnant women with atypical EVD, subsequent transmission events perinatal care.ResultsThe (ages 18–38) were all...
Introduction: Influenza-associated severe acute respiratory infections (SARI) are a major contributor to global morbidity and for influenza A(H1N1)pdm09, an investigation was initiated determine whether there increase of paediatric SARI diagnoses compatible with SARI.months (Interquartile range: 2-14 months).Children aged less than 5 years had higher rate 1.7 [95% CI: 1.1-2.6]).This not observed in children 5-14 years.The case-fatality ratio Conclusion:The enabled targeted public health...
Abstract Objectives To introduce the Laboratory Quality Stepwise Implementation ( LQSI ) tool and provide data about its roll‐out, usage effectiveness in assisting laboratories with quality improvement. Methods The tool, a freely available stepwise guide, was developed by WHO to assist efficiently implementing management system. Results Since tool's launch 2014, it has been accessed 130 986 unique users from 195 of 206 listed states. Of 35 respondents survey, 12 (34%) indicated that their...
HepB LiveTest is a machine learning decision support system developed for the early detection of hepatitis B virus (HBV). However, there lack evidence on its generalisability. In this study, we aimed to externally assess clinical validity and portability in predicting HBV infection among independent patient cohorts from Nigeria Australia. The performance was evaluated by constructing receiver operating characteristic curves estimating area under curve. Delong’s method used estimate 95%...
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