A5086467884- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Sepsis Diagnosis and Treatment
- Central Venous Catheters and Hemodialysis
- Patient Satisfaction in Healthcare
- Infection Control and Ventilation
- COVID-19 Pandemic Impacts
- COVID-19 epidemiological studies
- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- Clostridium difficile and Clostridium perfringens research
- Urinary Tract Infections Management
- Gastroesophageal reflux and treatments
- Animal Virus Infections Studies
- Data-Driven Disease Surveillance
- Microscopic Colitis
- Healthcare Quality and Management
- COVID-19 and Mental Health
- Acute Ischemic Stroke Management
- Clinical practice guidelines implementation
- Cardiovascular Syncope and Autonomic Disorders
- SARS-CoV-2 detection and testing
Johns Hopkins Hospital
2017-2025
Johns Hopkins University
2021-2024
Johns Hopkins Medicine
2021-2024
Society for Healthcare Epidemiology of America
2019
Engineering Associates (United States)
2018
Discussion | In the United States in 2020, we found that proportion of community-dwelling homebound adults aged 70 years or older substantially increased, particularly among Black non-Hispanic and Hispanic/Latino individuals.Although our study could not establish reasons for this first major increase population a decade, likely explanation is compliance with social distancing other public health recommendations to minimize risk infection SARS-CoV-2.Our also notable racial ethnic...
Interventions to optimize blood culture (BCx) practices in adult inpatients are limited. We conducted a before-after study evaluating the impact of diagnostic stewardship program that aimed BCx use medical intensive care unit (MICU) and five medicine units at large academic center. The included implementation an evidence-based algorithm detailing indications for education feedback providers about rates indication inappropriateness. Neutropenic patients were excluded.
Importance Blood culture (BC) use benchmarks in US hospitals have not been defined. Objective To characterize BC adult intensive care units (ICUs) and wards hospitals. Design, Setting, Participants A retrospective cross-sectional study of medical ICUs, medical-surgical wards, from acute the 4 geographic regions was conducted. Critical access hospitals, less than 6 months data, non-US were excluded. The included data September 1, 2019, to August 31, 2021. Data analyzed February 23 July 14,...
Abstract Background: Targeted screening for carbapenem-resistant organisms (CROs), including Enterobacteriaceae (CRE) and carbapenemase-producing (CPOs), remains limited; recent data suggest that existing policies miss many carriers. Objective: Our objective was to measure the prevalence of CRO CPO perirectal colonization at hospital unit admission use machine learning methods predict probability and/or carriage. Methods: We performed an observational cohort study all patients admitted...
OBJECTIVES The role of methicillin-resistant Staphylococcus aureus (MRSA) nasal surveillance swabs (nasal swabs) in guiding decisions about prescribing vancomycin is unclear. We aimed to determine the likelihood that patients with negative MRSA develop subsequent infections; assess avoidable days for swabs; and identify risk factors having a swab developing infection during intensive care unit (ICU) stay. METHODS This retrospective cohort study was conducted 6 ICUs at tertiary-care hospital...
SARS-CoV-2 antibody levels wane following two-doses of mRNA vaccination. An booster dose provides increased protection against hospitalization and death. We demonstrated that a significant increase in the neutralization Beta, Delta Omicron variants addition to an vaccine strain. The total spike IgG measurements, obtained by using commercial kits target protein from strain, may not reflect serum concern. IMPORTANCE This study found little no neutralizing capability 2-dose series omicron...
Abstract Using samples collected for VRE surveillance, we evaluated unit admission prevalence of carbapenem-resistant Enterobacteriaceae (CRE) perirectal colonization and whether CRE carriers (unknown to staff) were on contact precautions other indications. at was infrequent (3.9%). Most not precautions, representing a reservoir healthcare-associated transmission.
Abstract The epidemiology of community-onset Staphylococcus aureus infections is evolving. We performed a multihospital, retrospective study pediatric S. susceptibilities between 2015 and 2020. Oxacillin clindamycin susceptibility remained lower at 67% 75%, respectively. Tetracycline trimethoprim-sulfamethoxazole high >90%. was highest in invasive infections.
There are no systematic measures of central line-associated bloodstream infections (CLABSIs) in patients maintaining venous catheters (CVCs) outside acute care hospitals. To clarify the burden CLABSIs these patients, we characterized with CLABSI present on hospital admission (POA).
In a large healthcare worker cohort, we quantified the association between behaviors and risk of coronavirus disease 2019 (COVID-19) during different pandemic phases, adjusting for prior infection vaccination. Individual characteristics, including personal concerns, were associated with these behaviors. Public health messaging should target high-risk populations as evolves.
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Background One strategy for supporting a hospital or health system's board of directors (Board), with their quality oversight responsibility is to review the organization's performance on measures. But large systems, number measures needing quite burdensome and makes priority setting difficult. Our goal was develop scoring method that summarizes multiple together, while still maintaining Board's opportunity examine individual where there are specific concerns. Methods We calculated an...
Abstract Background Central line-associated bloodstream infections (CLABSI) lead to significant morbidity and mortality. Surveillance has contributed reductions in the CLABSI rate acute care hospitals. Although there are increasing numbers of patients with central venous catheters outside hospitals, prevalence mortality risk associated CLABSIs present-on-admission (POA) hospitals is unknown. To explore burden POA factors an all-cause Methods We identified presenting (regardless pre-admission...
Abstract Background National estimates of central line-associated bloodstream infections (CLABSI) focus on acute care hospital settings. Little is known about CLABSI that develop outside hospitals and are present admission (CLABSI-POA). We aimed to describe the epidemiology CLABSI-POA appropriate prevention strategies. Methods performed a retrospective cohort study all adult pediatric patients admitted from 11/01/2020 10/31/2021 in two large medical systems US, one Maryland Missouri....
Staff safety is paramount when managing an infectious disease event. However, early data from the COVID-19 pandemic suggested that staff compliance with personal protective equipment and other protocols was poor. In response to patient surges, many hospitals created dedicated "biomode" units provide care for patients infected SARS-CoV-2, virus causes COVID-19. To enhance on biomode during transports, our hospital a officer/transport officer (SO/TSO) program. The first SOs/TSOs were nurses,...
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Abstract Background The role of MRSA nasal surveillance swabs in guiding decisions about need for subsequent vancomycin therapy is unclear. Our objectives were to (1) determine the likelihood that patients with negative went on develop infections during same hospitalizations assess if could be avoided once swab result returns negative, (2) days potentially avoided, and (3) identify risk factors having a developing an infection hospital stay. Methods This retrospective cohort study was...
Abstract Background Clostridium difficile LabID event reporting uses electronic laboratory results without chart review. Nucleic acid amplification testing is common in the US. A positive result may represent colonization or C. diff infection (CDI). We review C.difflabID events to ascertain if Hospital-Onest CDI (HO CDI). For non-HO CDI, we identify reason and use a matrix prioritize clinical areas for intervention efforts. Methods Each difflab ID from Jan 2015 June 2016 at academic center...
An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.
An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.