A5021220910- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Reproductive tract infections research
- Adolescent Sexual and Reproductive Health
- Syphilis Diagnosis and Treatment
- Sex work and related issues
- LGBTQ Health, Identity, and Policy
- Global Maternal and Child Health
- Poverty, Education, and Child Welfare
- Homelessness and Social Issues
- Child Nutrition and Water Access
- Intimate Partner and Family Violence
- Genital Health and Disease
- HIV/AIDS Impact and Responses
- Blood Pressure and Hypertension Studies
- Sepsis Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Central Venous Catheters and Hemodialysis
- HIV Research and Treatment
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Focus Groups and Qualitative Methods
- Public Health Policies and Education
- Heart Rate Variability and Autonomic Control
Johns Hopkins University
2016-2025
Johns Hopkins Medicine
2016-2025
Baltimore City Health Department
2014-2024
University Hospital of Basel
2023-2024
New York City Department of Health and Mental Hygiene
2023
Centers for Disease Control and Prevention
2023
District of Columbia Department of Health
2023
The Centers
2023
Louisiana State Department of Health and Hospitals
2023
University of Alabama at Birmingham
2023
Gonorrhea (GC) and chlamydia (CT) are the most commonly reported notifiable diseases in United States. The Centers for Disease Control Prevention recommends that men who have sex with (MSM) be screened urogenital GC/CT, rectal pharyngeal GC. We describe extragenital GC/CT testing infections among MSM attending sexually transmitted disease (STD) clinics.The STD Surveillance Network collects patient data from 42 clinics. assessed proportion of these clinics during July 2011-June 2012 were...
Social capital—especially through its “network” dimension (high levels of participation in local community groups)—is thought to be an important determinant health many contexts. We investigate effect on HIV prevention, using prospective data from a general population cohort eastern Zimbabwe spanning period extensive behavior change (1998–2003). Almost half the initially uninfected women interviewed were members at least one group. In analysis 88 communities, individuals with higher group...
Inequalities in Neisseria gonorrhoeae (gonorrhea) burden by sexual minority status the United States are difficult to quantify. Sex of sex partner is not routinely collected for reported cases. Population estimates men who have with (MSM) necessary calculate case rates been available until recently. For these reasons, trends gonorrhea among MSM described across multiple jurisdictions.We estimated number cases 6 jurisdictions continuously participating STD Surveillance Network 2010-2015 based...
Background Transgender women and transgender men are disproportionately affected by human immunodeficiency virus (HIV) infection may be vulnerable to other sexually transmitted diseases (STDs), but the lack of surveillance data inclusive gender identity hinders prevention intervention strategies. Methods We analyzed from 506 (1045 total visits) 120 (209 who attended 26 publicly funded clinics that provide STD services in 6 US cities during a 3.5-year observation period. used clinical...
Background Antibiotic use for early-onset neonatal sepsis (EONS) is common, but prolonged exposure can lead to poor outcomes. Laboratory capacity and infection prevention initiatives may impact antibiotic EONS in intensive care units. The objective of this study was examine the influence institutional on prescribing India. Methods Between September 2023 January 2024, we surveyed Indian paediatricians neonatologists regarding practices EONS. Five vignettes with varying maternal infant risk...
Importance Neonates requiring intensive care are at high risk of health care–associated infections. In neonatal units (NICUs) in low-resource settings, the identification modifiable factors can inform targeted prevention strategies to reduce global burden morbidity and mortality. Objective To describe incidence associated with bloodstream infections (BSIs) NICUs Pune, India. Design, Setting, Participants This multicenter prospective cohort study enrolled all neonates admitted 3 India, from...
Abstract Postpartum hypertension (PPHT) affects 20% of pregnancies and is strongly correlated to cardiovascular kidney disease. Most outcome data stems from preeclampsia (PE) neglecting other hypertensive disorders pregnancy (HDP). This analysis aimed investigate blood pressure (BP) control, BP phenotypes, therapeutic intensity scores (TIS), albuminuria across the spectrum PPHT in short-medium term.This prospectively followed 370 cases PPHT. Automated office measurements (AOBPM), 24-hour...
Abstract Objective To compare socio‐demographic patterns in access to antiretroviral therapy (ART) across four community HIV cohort studies Africa. Methods Data on voluntary counselling and testing ART use among HIV‐infected persons were analysed from Karonga (Malawi), Kisesa (Tanzania), Masaka (Uganda) Manicaland (Zimbabwe), where free provision started between 2004 2007. coverage was compared sites by calculating the proportion those estimated need treatment, age, sex educational...
Recent data from the Manicaland HIV/STD Prevention Project, a general-population open HIV cohort study, suggested that between 2004 and 2007 prevalence amongst males aged 15–17 years in eastern Zimbabwe increased 1.20% to 2.23%, females remained unchanged at 2.23% 2.39%, while continued decline rest of adult population. We assess whether more likely source increase adolescent is recent sexual acquisition, or aging long-term survivors perinatal acquisition occurred during early growth...
Background Extragenital gonorrhea (GC) and chlamydia (CT) are usually asymptomatic only detected through screening. Ceftriaxone plus azithromycin is the recommended GC treatment; monotherapy (azithromycin or doxycycline) for CT. In urethral CT-positive/urethral GC-negative persons who not screened extragenitally, CT can lead to undertreatment may foster development of gonococcal antimicrobial resistance. We assessed extragenital positivity among men have sex with (MSM) attending sexually...
In the context of increasing syphilis rates, particularly among Black men who have sex (MSM), objectives were to determine associations between methamphetamine (meth) use and HIV positivity, identify partner meeting venues as potential intervention access points MSM in a mid-Atlantic US city.This study is an ongoing longitudinal cohort study. Participants recruited from clinical nonclinical settings included sexually active aged 18 45 years. The baseline visit behavioral survey testing for...
The impact of coronavirus disease 2019 (COVID-19) mitigation measures on sexually transmitted infection (STI) transmission and racial disparities remains unknown. Our objectives were to compare sex drug risk behaviors, access sexual health services, STI positivity overall by race during the COVID-19 pandemic compared with pre-pandemic among urban minority men (MSM).
There is variation in microbiology testing among PICU patients with fever offering opportunities to reduce avoidable and treatment. Our objective describe the development assess impact of a novel comprehensive algorithm support judicious practices expanded diagnostic differentials for new or instability.A mixed-methods quality improvement study.Single-center academic pediatric cardiac ICU.Admitted physicians.A multidisciplinary team developed clinical decision-support algorithm.We evaluated...
Objective: There is an increasing number of cuffless blood pressure (BP) measurement (BPM) devices. Despite promising results when comparing single measurements, the ability these devices to track changes in BP levels over 24 h related initial calibration (CalibBP) unknown. Our aim was analyse this a device using pulse transit time. Methods: We prospectively enrolled 166 participants for simultaneously performed (Somnotouch-NIBP) and cuff-based (Spacelabs 90217A/IEM Mobil-O-graph) BPM. As...
Unconditional and conditional cash transfer programmes (UCT CCT) show potential to improve the well-being of orphans other children made vulnerable by HIV/AIDS (OVC). We address gap in current understanding about extent which household-based transfers differentially impact individual children's outcomes, according risk or protective factors such as orphan status household assets. Data were obtained from a cluster-randomised controlled trial eastern Zimbabwe, with random assignment three...
To examine the prevalence and treatment of rectal Chlamydia trachomatis Neisseria gonorrhoeae infections among women reporting receptive anal intercourse in a network sexually transmitted disease or sexual health clinics estimate proportion missed if were tested at genital site only.We conducted cross-sectional analysis C N test results from female patients preceding 3 months during visits to 24 2015 2016. Primary outcomes interest 1) anatomic site-specific testing positivity attending...
Reducing HIV incidence requires addressing persistent racial/ethnic disparities in burden. Our goal was to evaluate preexposure prophylaxis (PrEP) delivery, overall and relative community need, among 7 clinical sites participating a health department-led demonstration project increase PrEP Baltimore city, MD.
Background Religion is an important underlying determinant of HIV spread in sub-Saharan Africa. However, little known about how religion influences changes prevalence and associated sexual behaviours over time. Objectives To compare between major religious groups eastern Zimbabwe during a period substantial risk reduction (1998–2005) to investigate whether variations observed can be explained by differences behaviour change. Methods We analysed serial cross-sectional data from two rounds...
In Brief Background Replacing oral treatments with ceftriaxone is a central component of public health efforts to slow the emergence cephalosporin-resistant Neisseria gonorrhoeae in United States; US gonorrhea treatment guidelines were revised accordingly 2010. However, current practices have not been well characterized. Methods Six city and state departments Cycle II STD Surveillance Network (SSuN) contributed data on all cases reported 101 counties independent cities. Treatment obtained...
Introduction In an HIV/AIDS epidemic driven primarily by heterosexual transmission, it is important to have understanding of the human sexual behaviour patterns that influence transmission. We analysed distribution and predictors within-partnership condom use in rural Zimbabwe generated parameters for future modelling analyses. Methods A population-based cohort was recruited from a household census 12 communities. baseline survey carried out 1998–2000 with follow-up surveys after 3 5 years....
The release of the first drug for human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) in 2012 marked beginning a new era HIV prevention. Although PrEP is highly efficacious, identifying and ultimately increasing uptake among highest risk male subgroups remains challenge. Public health surveillance data from 2009 to 2016 was used evaluate an diagnosis after syphilis (ie, primary, secondary, or early latent), gonorrhea, repeat diagnoses urban males, including men who have sex...