- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Outbreaks Research
- Antibiotic Use and Resistance
- Disaster Response and Management
- Neonatal and Maternal Infections
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Bacterial Identification and Susceptibility Testing
- Vaccine Coverage and Hesitancy
- Viral Infections and Vectors
- Pelvic floor disorders treatments
- Influenza Virus Research Studies
- Female Genital Mutilation/Cutting Issues
- Genital Health and Disease
- COVID-19 Digital Contact Tracing
- Surgical site infection prevention
- Urologic and reproductive health conditions
- Global Maternal and Child Health
- COVID-19 and healthcare impacts
- Data-Driven Disease Surveillance
- COVID-19 and Mental Health
- Emergency and Acute Care Studies
- Maternal and Perinatal Health Interventions
Centers for Disease Control and Prevention
2014-2025
New York Proton Center
2024
Communities In Schools of Orange County
2024
University of Pittsburgh
2024
Lindsay Unified School District
2024
Oregon Medical Research Center
2024
National Center for Emerging and Zoonotic Infectious Diseases
2020-2022
The Centers
2022
University of Illinois Chicago
2006-2016
Ministry of Health and Social Welfare
2016
The high morbidity and mortality of necrotizing fasciitis (NF) supports the need for epidemiological studies to characterize disease identify patient factors associated with adverse outcomes. A multi-site medical record review patients diagnosed NF was performed (n=80, 15%). Variables collected were hypothesized have association outcomes from NF, multivariable analysis used detect any such in this population. Select included evidence underlying conditions (P=0.002), advanced age (P=0.04),...
Abstract Following the endorsement by World Health Organization (WHO) and Joint United Nations Programme on HIV/AIDS (UNAIDS) of male circumcision as an additional strategy to HIV prevention, initiatives introduce safe, voluntary medical (VMMC) services commenced in 2008 several sub-Saharan African communities. Information regarding perceptions a method however, is largely limited data collected before this important associated increase availability VMMC services. To address this, we...
Importance Neonates requiring intensive care are at high risk of health care–associated infections. In neonatal units (NICUs) in low-resource settings, the identification modifiable factors can inform targeted prevention strategies to reduce global burden morbidity and mortality. Objective To describe incidence associated with bloodstream infections (BSIs) NICUs Pune, India. Design, Setting, Participants This multicenter prospective cohort study enrolled all neonates admitted 3 India, from...
Human adenovirus type 3 (HAdV-3) causes severe respiratory illness in children, but outbreaks long-term care facilities have not been frequently reported. We describe an outbreak of HAdV-3 infection a facility for children with neurologic impairment, where only 63 residents were ambulatory.A clinical case was defined as fever (temperature, > or = 38.0 degrees C) and either worsening symptoms conjunctivitis resident, onset from June through August 2005. reviewed medical records; conducted...
Background Globally, over 400,000 neonatal deaths in 2015 were attributed to sepsis, however, the incidence and etiologies of these infections are largely unknown low-middle income countries. We aimed determine etiology community-acquired early-onset (<72 hours age) sepsis (EOS) using culture molecular diagnostics. Methods This was a prospective observational study, which we conducted surveillance for pathogens combination blood polymerase chain reaction (PCR)-based test. Blood performed on...
Abstract Background Antimicrobial resistance (AMR) is a growing threat to newborns in low- and middle-income countries (LMIC). Methods We performed prospective cohort study 3 tertiary neonatal intensive care units (NICUs) Pune, India, describe the epidemiology of bloodstream infections (BSIs). All neonates admitted NICU were enrolled. The primary outcome was BSI, defined as positive blood culture. Early-onset BSI on day life (DOL) 0–2 late-onset DOL or later. Results From 1 May 2017 until 30...
Abstract Background Drug-resistant gram-negative (GN) pathogens are a common cause of neonatal sepsis in low- and middle-income countries. Identifying GN transmission patterns is vital to inform preventive efforts. Methods We conducted prospective cohort study, 12 October 2018 31 2019 describe the association maternal environmental colonization with bloodstream infection (BSI) among neonates admitted intensive care unit (NICU) Western India. assessed rectal vaginal pregnant women presenting...
We measured the reproduction number before and after interventions were implemented to reduce Ebola transmission in 9 outbreaks Liberia during 2014. evaluated risk factors for secondary cases association between patient admission an treatment unit (ETU) survival. The declined 94% from 1.7 (95% CI 1.1-2.6) 0.1 0.02-0.6) began. infections was 90% lower patients admitted ETU (risk ratio 0.1, 95% 0.04-0.3) than those who died community. case-fatality rate 68% 60-74), associated with a 50%...
Coronavirus disease 2019 (COVID-19), the respiratory caused by severe acute syndrome coronavirus 2 (SARS-CoV-2), was first identified in Wuhan, China and has since become pandemic. In response to cases United States, close contacts of confirmed COVID-19 were investigated enable early identification isolation additional learn more about risk factors for transmission. Close nine travel-related States monitored daily development symptoms (active monitoring). Selected (including those with...
Using a population-based survey we examined the behaviors, beliefs, and HIV/HSV-2 serostatus of men women in traditionally non-circumcising community Kisumu, Kenya prior to establishment voluntary medical male circumcision services. A total 749 906 participated. Circumcision status was not associated with infection nor increased high risk sexual behaviors. In males, preference for being or becoming circumcised inconsistent condom use lifetime number partners. Preference understanding that...
Objective: To implement the Comprehensive Unit-based Safety Program (CUSP) in four neonatal intensive care units (NICUs) Pune, India, to improve infection prevention and control (IPC) practices. Design: In this quasi-experimental study, we implemented CUSP NICUs IPC practices three focus areas: hand hygiene, aseptic technique for invasive procedures, medication intravenous fluid preparation administration. Sites received training methodology, formed multidisciplinary teams, selected...
Three randomized controlled trials showed that voluntary medical male circumcision (VMMC) reduces the risk of female-to-male HIV transmission by approximately 60%. However, data from communities where VMMC programs have been implemented are needed to assess changes in prevalence and whether men women compensate for perceived reductions increasing their behaviors.Scale-up free began Kisumu, Kenya 2008. Between 2009 2013, a sequence 3 unlinked cross-sectional surveys were conducted. All...
We examined SARS-CoV-2 anti-spike 1 IgG antibody levels following COVID-19 vaccination (AstraZeneca [AZ], Sinovac [SV], Pfizer-BioNTech [PZ]) among Thai healthcare providers.
In 2014, as part of the Global Health Security Agenda, Ethiopia was provided technical and financial resources needed to prioritize antimicrobial resistance (AMR) in national public health sphere. Under direction a multi-stakeholder working group, AMR surveillance launched July 2017 at 4 sentinel sites across country. The initiative represents one first systematic efforts prospectively collect, analyze, report national-level microbiology results from network hospitals laboratories Baseline...
Abstract Objective: Studies evaluating the incidence, source, and preventability of hospital-onset bacteremia fungemia (HOB), defined as any positive blood culture obtained after 3 calendar days hospital admission, are lacking in low- middle-income countries (LMICs). Design, setting, participants: All consecutive cultures performed for 6 months during 2020–2021 2 hospitals India were reviewed to assess HOB National Healthcare Safety Network (NHSN) reportable central-line–associated...
Abstract Persons who died of Ebola virus disease at home in rural communities Liberia and Guinea resulted more secondary infections than persons admitted to treatment units. Intensified monitoring contacts this the community is an evidence-based approach reduce transmission communities.
ABSTRACT Background Coronavirus disease 2019 (COVID-19), the respiratory caused by severe acute syndrome coronavirus 2 (SARS-CoV-2), was first identified in Wuhan, China and has since become pandemic. As part of initial response activities United States, enhanced contact investigations were conducted to enable early identification isolation additional cases learn more about risk factors for transmission. Methods Close contacts nine travel-related States identified. meeting criteria active...
Background. From January 2014–July 2014, more than 46 000 unaccompanied children (UC) from Central America crossed the US–Mexico border. In June–July, UC aged 9–17 years in 4 shelters and 1 processing center states were hospitalized with acute respiratory illness. We conducted a multistate investigation to interrupt disease transmission. Methods. Medical charts abstracted for UC. Nonhospitalized influenza-like illness interviewed, nasopharyngeal oropharyngeal swabs collected detect...