- Antibiotic Use and Resistance
- Infection Control in Healthcare
- Pneumonia and Respiratory Infections
- Parasitic Diseases Research and Treatment
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Bacterial Identification and Susceptibility Testing
- COVID-19 Clinical Research Studies
- Disaster Response and Management
- Nosocomial Infections in ICU
- Pneumocystis jirovecii pneumonia detection and treatment
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Streptococcal Infections and Treatments
- Infection Control and Ventilation
- Antibiotic Resistance in Bacteria
- Patient Satisfaction in Healthcare
- Medical Device Sterilization and Disinfection
- Food Safety and Hygiene
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Neonatal and Maternal Infections
- Dental Research and COVID-19
Robert Koch Institute
2020-2024
World Health Organization
2018-2021
University of Geneva
2018-2020
Centers for Disease Control and Prevention
2014-2019
Instituut voor Tropische Geneeskunde
2013-2017
Epidemic Intelligence Service
2016-2017
National Center for Immunization and Respiratory Diseases
2017
Cairo University
2016
Ministry of Health
2015-2016
King Abdulaziz University
2015-2016
A marked increase in the number of cases Middle East respiratory syndrome coronavirus (MERS-CoV) infection occurred Jeddah, Saudi Arabia, early 2014. We evaluated patients with MERS-CoV Jeddah to explore reasons for this and assess epidemiologic clinical features disease.We identified all laboratory-confirmed that were reported Arabian Ministry Health from January 1 through May 16, conducted telephone interviews symptomatic who not health care personnel, we reviewed hospital records. as...
Acute respiratory infection (ARI) is an important cause of mortality in children and adults. However, studies assessing risk factors for ARI-related deaths low- middle-income settings are limited. We describe death associated among aged < 2 years adults ≥18 hospitalized with ARI Guatemala.We used illness surveillance data Guatemala from 2007 to 2013. was defined as evidence acute ≥ 1 sign/symptom disease patients. Clinical, sociodemographic, follow-up were gathered....
Abstract Objectives The COVID-19 pandemic has had a substantial impact on health systems. WHO Antimicrobial Resistance (AMR) Surveillance and Quality Assessment Collaborating Centres Network conducted survey to assess the effects of AMR surveillance, prevention control. Methods From October December 2020, Global Use System (GLASS) national focal points completed questionnaire, including Likert scales open-ended questions. Data were descriptively analysed, income/regional differences assessed...
Hand hygiene is at the core of effective infection prevention and control (IPC) programmes. 10 years after development WHO Multimodal Hygiene Improvement Strategy, we aimed to ascertain level hand implementation its drivers in health-care facilities through a global survey.From Jan 16 Dec 31, 2019, IPC professionals were invited email campaigns complete online Self-Assessment Framework (HHSAF). A geospatial clustering algorithm selected unique responses post-stratification weighting was...
Antibiotic-nonsusceptible invasive pneumococcal disease (IPD) decreased substantially after the US introduction of pediatric 7-valent conjugate vaccine (PCV7) in 2000. However, rates antibiotic-nonsusceptible non-PCV7-type IPD increased during 2004-2009. In 2010, 13-valent (PCV13) replaced PCV7. We assessed impact PCV13 on rates.We defined as isolation from a normally sterile site resident 10 surveillance sites. isolates were those intermediate or resistant to ≥1 antibiotic classes according...
Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) causes a spectrum of illness. We evaluated whether cycle threshold (Ct) values (which are inversely related to virus load) were associated with clinical severity in patients from Saudi Arabia whose nasopharyngeal specimens tested positive for this by real-time reverse transcription PCR. Among 102 patients, median Ct 31.0 the upstream E gene target 41 (40%) who died was significantly lower than 33.0 61 survivors (p = 0.0087). In...
BackgroundStrengthening infection prevention and control (IPC) is essential to combat healthcare-associated infections, antimicrobial resistance, prevent respond outbreaks.AimTo assess national IPC programmes worldwide according the World Health Organization (WHO) core components.MethodsBetween June 1st, 2017 November 30th, 2018, a multi-country, cross-sectional study was conducted, based on semi-structured interviews with focal points of countries that pledged WHO 'Clean Care Safer Care'...
Background Podoconiosis is a neglected tropical disease (NTD) that prevalent in red clay soil-covered highlands of Africa, Central and South America, northern India. It estimated up to one million cases exist Ethiopia. This study aimed estimate the prevalence podoconiosis East West Gojam Zones Amhara Region Methodology/Principal Findings A cross-sectional household survey was conducted Debre Eliyas Dembecha woredas (districts) Zones, respectively. The covered all 17,553 households 20 kebeles...
Abstract Background Exposure to antibiotics has been shown be one of the drivers antimicrobial resistance (AMR) and is critical address when planning implementing strategies for combatting AMR. However, data on antibiotic use in sub-Saharan Africa are still limited. Using hospital-based surveillance from African Network Improved Diagnostics, Epidemiology Management Common Infectious Agents (ANDEMIA), we assessed self-reported multiple countries. Methods ANDEMIA included 12 urban rural health...
During March-May 2014, a Middle East respiratory syndrome (MERS) outbreak occurred in Jeddah, Saudi Arabia, that included many persons who worked or received medical treatment at King Fahd General Hospital. We investigated 78 had laboratory-confirmed MERS during March 2-May 10 and documented contact this hospital. The with comprised 53 patients, 16 healthcare workers, 9 visitors. Among the most probable sites of acquisition were emergency department (22 patients), inpatient areas (17),...
Around 5–15% of all hospital patients worldwide suffer from healthcare-associated infections (HAIs), and years excessive antimicrobial use in human animal medicine have created emerging resistance (AMR). A considerable amount evidence-based measures been published to address these challenges, but the largest challenge seems be their implementation. In June 2017, a total 42 experts convened at Geneva IPC-Think Tank discuss four domains implementation science: 1) teaching skills; 2) fostering...
Podoconiosis is a form of non-filarial elephantiasis that affects barefoot individuals in highland tropical areas. The disease presents with bilateral, asymmetric swelling the legs, usually confined to below knee. This study aimed assess podoconiosis patients' perceptions prevention, control, causes and familial clustering disease, document physical, social economic impairments associated ultimate aim enabling development tailored interventions this region. descriptive part largest...
The stigma, deformity and disability related to most neglected tropical diseases may lead poor mental health. We aimed assess the comorbidity of podoconiosis distress.A comparative cross-sectional study was conducted in 2012, including 346 people with 349 healthy neighbourhood controls. Symptoms distress were assessed using validated Amharic translation Kessler-10 scale (K10). A linear regression analysis identify factors associated distress.The mean K10 score 15.92 (95% CI: 15.27 16.57)...
Podoconiosis, or non-filarial elephantiasis, is a neglected tropical disease (NTD) characterised by swelling of the lower legs. When left untreated, this disfiguring condition has significant social impact. This study aimed to describe stigma experience among podoconiosis patients in Dembecha, Northern Ethiopia and assess potential associations between sociodemographic determinants. The was conducted May 2012 Ethiopia. A questionnaire-based cross-sectional design used assessed using...