A5101548345- Antibiotic Use and Resistance
- Geriatric Care and Nursing Homes
- Streptococcal Infections and Treatments
- Patient Satisfaction in Healthcare
- Bacterial Identification and Susceptibility Testing
- Global Maternal and Child Health
- Antibiotic Resistance in Bacteria
- Travel-related health issues
- Viral Infections and Vectors
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Antimicrobial Resistance in Staphylococcus
- Nosocomial Infections in ICU
- Neonatal and Maternal Infections
- SARS-CoV-2 detection and testing
- Toxoplasma gondii Research Studies
- Tuberculosis Research and Epidemiology
- Viral Infections and Outbreaks Research
- Medical Device Sterilization and Disinfection
- Vibrio bacteria research studies
- Complementary and Alternative Medicine Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Parasitic Infections and Diagnostics
- Maternal and fetal healthcare
- Listeria monocytogenes in Food Safety
Public Health England
2014-2021
Government of the United Kingdom
2020
University College London
1997-2015
University College London Hospitals NHS Foundation Trust
1997-2015
Special Olympics
2012
Christian Medical College & Hospital
2005
Schieffelin Institute of Health Research and Leprosy Centre
2005
International Center for Research on Women
2005
Czech Academy of Sciences, Institute of Microbiology
2005
China Science and Technology Publishing & Media
2001
Abstract Objectives The COVID-19 pandemic has had a substantial impact on health systems. WHO Antimicrobial Resistance (AMR) Surveillance and Quality Assessment Collaborating Centres Network conducted survey to assess the effects of AMR surveillance, prevention control. Methods From October December 2020, Global Use System (GLASS) national focal points completed questionnaire, including Likert scales open-ended questions. Data were descriptively analysed, income/regional differences assessed...
CONTEXT: Women often suffer silently with reproductive tract infections (RTIs).Studies of the prevalence these in South Asia have been hindered by low participation rates, and little is known about rates among youngest married women. METHODS:A community-based cross-sectional study RTIs was conducted 1996-1997 women 16-22 years age Tamil Nadu, India.The were questioned symptoms, received pelvic speculum examinations provided samples for laboratory tests.Qualitative quantitative data on...
Primary infection with Toxoplasma gondii in pregnancy can result miscarriage, hydrocephalus, cerebral calcification and chorioretinitis the newborn. The objective of our study was to evaluate seroprevalence analyse risk factors for toxoplasmosis antenatal women from 2006 2008 an ethnically diverse population Central London re-examine need a screening policy.We performed serum IgG estimations T. using commercial kit, analysed acquisition questionnaire.Seroprevalence 17.32% 2610 samples...
To estimate UK prevalence and incidence of clinically significant carbapenemase-producing Enterobacteriaceae (CPE), to determine epidemiological characteristics, laboratory methods infection prevention control (IPC) measures in acute care facilities.A 6 month survey was undertaken November 2013-April 2014 21 sentinel laboratories as part the European Survey on Carbapenemase-Producing (EuSCAPE) project. Up 10 consecutive, non-duplicate, carbapenem-non-susceptible isolates Escherichia coli or...
Evidence to inform decontamination practices at Ebola holding units (EHUs) and treatment centres is lacking. We conducted an audit of procedures inside Connaught Hospital EHU in Freetown, Sierra Leone, by assessing environmental swab specimens for evidence contamination with virus RT-PCR. Swabs were collected following discharge Virus Disease (EVD) patients before after routine decontamination. Prior decontamination, RNA was detected within a limited area all bedside sites tested, but not...
This is the first report of molecular epidemiology Staphylococcus aureus from skin and soft tissue infections (SSTI) in Laos. We selected a random sample 96 S. SSTI isolates received by Microbiology Laboratory, Mahosot Hospital, Vientiane, between July 2012 June 2014, including representation seven referral hospitals. Isolates underwent susceptibility testing Clinical Laboratory Standards Institute methods, spa typing DNA microarray analysis, with whole genome sequencing for rare lineages....
To compare two molecular assays (rrs quantitative PCR (qPCR) versus a combined 16SrRNA and LipL32 qPCR) on different sample types for diagnosing leptospirosis in febrile patients presenting to Mahosot Hospital, Vientiane, Laos.Serum, buffy coat urine samples were collected admission, follow-up serum ∼10 days later. Leptospira spp. culture microscopic agglutination tests (MAT) performed as reference standards. Bayesian latent class modelling was estimate sensitivity specificity of each...
Abstract Introduction Previous investigations have identified high rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among residents and staff in care homes reporting an outbreak disease 2019 (COVID-19). We investigated a single suspected or confirmed case to assess whether early mass testing might reduce risk transmission during the peak pandemic London. Methods Between 18 27 April 2020, COVID-19 Public Health England had nasal swab test for SARS-CoV-2 by...
To assess the incidence of maternal group B Streptococcus (GBS) infection in England.Population surveillance augmented through data linkage.England.All pregnant women accessing National Health Service (NHS) England.Invasive GBS (iGBS) infections during pregnancy or within 6 weeks childbirth were identified by linking Public England (PHE) national microbiology for 2014 to NHS hospital admission records. Capsular serotypes determined reference laboratory typing clinical isolates from aged...
Rigorous antimicrobial stewardship programmes (ASPs) are an essential strategy against resistance. To evaluate and score ASPs in acute English NHS hospitals determine association of ASP scores with prescribing. structure process were evaluated through online survey 148/152 2017. Scores assigned to quality indicators based on resource- labour-intensiveness, their total modified WHO-categorized 'Access', 'Watch' 'Reserve' (AwaRe) prescribing was analysed. The response rate 97% 78% trusts...
In recognition of the central importance surveillance and epidemiology in control antimicrobial resistance need to strengthen at all levels, Wellcome has brought together a new international expert group SEDRIC (Surveillance Epidemiology Drug Resistant Infections Consortium). aims advance transform ways tracking, sharing analysing rates infection drug resistance, burden disease, information on antibiotic use, opportunities for preventative measures such as vaccines, contamination...
ABSTRACT Background We investigated six London care homes experiencing a COVID-19 outbreak and found very high rates of SARS-CoV-2 infection among residents staff. Here we report follow-up serological analysis in these five weeks later. Methods Residents staff had convalescent blood sample for antibody levels neutralising antibodies by SARS-COV-2 RT-PCR after the primary investigation. Results Of 518 initial investigation, 208/241 (86.3%) surviving 186/254 (73.2%) underwent testing. Almost...
Background: Care homes are experiencing large outbreaks of coronavirus disease 2019 (COVID-19) associated with high case-fatality. We conducted detailed investigations in six London care reporting suspected COVID-19 during April 2020. Methods: Residents and staff had nasal swabs taken for SARS CoV-2 testing using RT-PCR were followed-up 14 days. They categorized as symptomatic, post-symptomatic or pre-symptomatic if they symptoms at the time testing, two weeks before after respectively,...