A5102738130- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Wound Healing and Treatments
- Central Venous Catheters and Hemodialysis
- Pressure Ulcer Prevention and Management
- Infective Endocarditis Diagnosis and Management
- Diabetic Foot Ulcer Assessment and Management
- Antibiotic Resistance in Bacteria
- Urinary Tract Infections Management
- Dialysis and Renal Disease Management
- Streptococcal Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Nosocomial Infections in ICU
- Pelvic floor disorders treatments
- Antifungal resistance and susceptibility
- Viral gastroenteritis research and epidemiology
- Surgical Sutures and Adhesives
- Bacteriophages and microbial interactions
- Bacterial biofilms and quorum sensing
- Surgical site infection prevention
- Antibiotic Use and Resistance
- Escherichia coli research studies
- Urinary Bladder and Prostate Research
- Amoebic Infections and Treatments
- Healthcare cost, quality, practices
Birmingham City University
2019-2024
Florida Cancer Specialists & Research Institute
2024
Salford Royal NHS Foundation Trust
2013-2023
Healthcare Infection Society
2023
Marymount University
2020
Salford Royal Hospital
2000-2016
University of Salford
1993-2015
Manchester Academic Health Science Centre
2015
Mott MacDonald (United Kingdom)
2014
New York Hospital Queens
2009
BackgroundStaphylococcus aureus bacteraemia is a common cause of severe community-acquired and hospital-acquired infection worldwide. We tested the hypothesis that adjunctive rifampicin would reduce bacteriologically confirmed treatment failure or disease recurrence, death, by enhancing early S killing, sterilising infected foci blood faster, reducing risks dissemination metastatic infection.MethodsIn this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years)...
The phenomenon of lysogeny was cited by Jacob and Monod in 1961 as an example gene control repressors. It hypothesized that each temperate phage produces a repressor which specifically blocks the functioning early genes phage. Since late function only if provided with certain products, proposed action would suffice to turn off all lytic genes, thereby permitting lysogenization. According these ideas, dormant resume upon removal repressor, it inducing agents, such UV light, inactivating repressor.
Background: Catheter‐related bloodstream infections (CRBSIs) are a serious complication in the provision of home parenteral nutrition (HPN). Antibiotic salvage central venous catheters (CVCs) CRBSI is recommended; however, this based on limited reports. We assessed efficacy antibiotic CRBSIs HPN patients. Materials and Methods : All confirmed occurring patients receiving national intestinal failure unit (IFU), between 1993 2011, were analyzed. A standardized protocol involving urokinase CVC...
No AccessJournal of Urology1 Nov 1981The Role Chlamydiae in Genitourinary Disease A.W. Bruce, P. Chadwick, W.S. Willett, and M. O’Shaughnessy BruceA.W. Bruce More articles by this author , ChadwickP. Chadwick WillettW.S. Willett O’ShaughnessyM. View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)54660-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The incidence chlamydial organisms early morning urine...
To estimate UK prevalence and incidence of clinically significant carbapenemase-producing Enterobacteriaceae (CPE), to determine epidemiological characteristics, laboratory methods infection prevention control (IPC) measures in acute care facilities.A 6 month survey was undertaken November 2013-April 2014 21 sentinel laboratories as part the European Survey on Carbapenemase-Producing (EuSCAPE) project. Up 10 consecutive, non-duplicate, carbapenem-non-susceptible isolates Escherichia coli or...
Background: The mechanisms which regulate cutaneous inflammation in the setting of collagen vascular disease have been a topic recent interest; emphasis has placed on type I interferon‐associated recruitment CXCR3+ lymphocytes dermatomyositis (DM). Methods: On total 42 biopsies from patients with DM, systemic lupus erythematosus (SLE), discoid (DLE) and subacute (SCLE) comprehensive phenotypic studies were performed to explore practical value analysis subclassification lesions disease....
To elucidate the cause of late operative site pain in six cases scoliosis managed with Isola posterior instrumentation that required removal implants.Microbiologic examination wound swabs and enriched culture tissue specimens was undertaken all cases. Histologic study peri-implant membranes also conducted.The presentation similar: back appearing between 12-20 months after surgery, followed by a local swelling leading to sinus. In only one these discharge positive for bacterial growth....
The adherence of several gram-negative uropathogens to human uroepithelial cells was examined with scanning and transmission electron microscopy, in vitro adhesion assays. bacteria studied demonstrated different extracellular structures: fimbria glycocalyx. Human were obtained from a bladder tumor cell line (T-24) groups patients, including those no history urinary tract infection (controls), recurrent infection, acute cystitis tumors before after bacillus Calmette-Guerin therapy. Results...
Summary We report a case of acute pancreatitis associated with campylobacter infection. The patient presented clinical symptoms and signs which suggested appendicitis. However, she was found to have an Recent reports shown that is pathogenic in the biliary tract, we suggest it may also be responsible for some cases absence disease.
Following a pneumocystis pneumonia (PCP) outbreak in our nephrology unit, all transplant patients were offered chemoprophylaxis with trimethoprim-sulphamethoxazole (TMP-SMX) as the first line agent. A high rate of complications was noted. We aimed to quantify TMP-SMX associated adverse events and evaluate its prophylactic benefit their light. Potential risk factors for complications' development also investigated.This an observational study outcomes recipients commenced on prophylaxis 1year...
The primary objective of this study was to evaluate the fluid management capabilities a superabsorbent wound dressing (Zetuvit Plus Silicone), with secondary objectives related parameters that support whether enables undisturbed healing.This an open labelled non-comparative study. Patients included in were selected by clinical investigator(s) according patient required for moderately highly exuding wounds.A total 50 patients Results demonstrated able absorb all levels exudate across range...