A5025338531- Travel-related health issues
- Bacterial Identification and Susceptibility Testing
- Disaster Response and Management
- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Antibiotic Use and Resistance
- Climate Change and Health Impacts
- Antibiotic Resistance in Bacteria
- Health and Conflict Studies
- Parasites and Host Interactions
- Urinary Tract Infections Management
- Microscopic Colitis
- Infection Control in Healthcare
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Ovarian cancer diagnosis and treatment
- Tumors and Oncological Cases
- Mosquito-borne diseases and control
- Infections and bacterial resistance
- Lymphadenopathy Diagnosis and Analysis
- Anesthesia and Sedative Agents
- Salmonella and Campylobacter epidemiology
- Amoebic Infections and Treatments
- Nosocomial Infections in ICU
- CAR-T cell therapy research
- Antimicrobial Resistance in Staphylococcus
North Bristol NHS Trust
2024
Southmead Hospital
2024
Royal Navy
2013-2021
Liverpool School of Tropical Medicine
2021
Guy's and St Thomas' NHS Foundation Trust
2014-2015
King's College London
2014-2015
St Thomas' Hospital
2013-2015
New York Proton Center
2015
Engineering Associates (United States)
2015
Iowa City Public Library
2015
BackgroundStaphylococcus aureus bacteraemia is a common cause of severe community-acquired and hospital-acquired infection worldwide. We tested the hypothesis that adjunctive rifampicin would reduce bacteriologically confirmed treatment failure or disease recurrence, death, by enhancing early S killing, sterilising infected foci blood faster, reducing risks dissemination metastatic infection.MethodsIn this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years)...
Background Gastrointestinal parasite (GIP) infections are a major cause of global morbidity, infecting hundreds millions people each year and potentially leading to lifelong infection serious complications. Few data exist on screening for GIP in migrants entering the UK or current performance different traditional diagnostic approaches. This study aimed describe prevalence Nepalese Gurkha recruits screened arrival UK. Methodology/Principal findings We present retrospective analysis from male...
Fidaxomicin is sporicidal and may be associated with a reduced time to resolution of diarrhoea when used treat patients Clostridium difficile infection (CDI). This study investigated whether fidaxomicin for treatment all CDI C. environmental contamination. Surfaces in the rooms 66 hospitalized treated metronidazole and/or vancomycin 68 were sampled. Patients less likely contaminate their environment (25/68, 36.8%) than (38/66 57.6%) (P = 0.02). Treatment was contamination difficile.
Clostridium difficile was recovered from 33 (34%) of 98 rooms patients who were excretors compared with 36 (49%) 73 active infection. Not all laboratory algorithms can distinguish between these 2 groups, yet both may be a significant source for ongoing transmission.
Diseases and non-battle injuries (DNBIs) are common on UK military deployments, but the collection analysis of clinically useful data these remain a challenge. Standard medical returns do not provide adequate clinical information, clinician-led approaches have been laudable, integrated nor standardised used long-term. Op TRENTON is novel humanitarian operation in support United Nations Mission South Sudan, which included deployment level 1 2 treatment facilities at Bentiu to healthcare for...
Abstract Cooperation between CD4 + T cells can enhance the response and modulate cytokine profile, defining these parameters has become a major issue for multivalent‐vaccine strategies.We explored cooperation using adoptive transfer of two populations TCR transgenic different specificity. One was transferred without prior activation, whereas second activatedfor five days by antigen stimulation under polarizing culture conditions. Both were into single host then primed particle‐mediated DNA...
Mycotic aneurysms, especially outside the aorta, are uncommon, with group A Streptococcus a particularly rare cause. We report case of extra-aortic mycotic aneurysm following sore throat without demonstrable bacteremia where identification pathological organism was made by molecular diagnostic techniques after standard laboratory culture negative.
Strongyloidiasis is associated with Gram-negative bacteremia. Septic portal vein thrombosis or pylephlebitis a rare but serious complication of intra-abdominal infection, and it often Bacteroides We present the first report bacteremia underlying Strongyloides stercoralis infection briefly review management septic thrombosis.
These are exciting but challenging times for all those involved in the management of patients with infection. The unrelenting appearance multi-drug resistant (MDR) organisms combined reduction numbers new antibiotics development is providing clinical challenges that have not
Disease non-battle injury has plagued British expeditionary forces through the ages. While in recent years significant mortality reduced, it had a large impact on operational effectiveness, at times leading to closure of major medical treatment facilities (MTFs). Infection Prevention and Control (IPC) benefits from subject matter expert champion ensure remains front people’s minds be hand manage acute dynamic situations. To mitigate lack an IPC Nursing Officer, we piloted deployed military...
A 77-year-old Caucasian male presented with productive cough for two days. He had lived in the UK all his life. multiple small nodules throughout neck consistent lymphadenopathy, a large scar on right side (Fig [1][1]). ![Fig 1.][2]</img> Fig 1. Scar of
Acute respiratory distress syndrome (ARDS) has a very high mortality and few interventions exist that have direct effect on the morbidity of this condition. Although previously used, neuromuscular blockade not been popular in recent years with long-term muscular weakness …