- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Bone health and osteoporosis research
- Bariatric Surgery and Outcomes
- Ginger and Zingiberaceae research
- Thyroid Disorders and Treatments
- Vitamin D Research Studies
- Pharmacological Effects of Natural Compounds
- Diet and metabolism studies
- Traditional Chinese Medicine Studies
- Adrenal and Paraganglionic Tumors
- Hip and Femur Fractures
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Tryptophan and brain disorders
- Vitamin C and Antioxidants Research
- Chronic Kidney Disease and Diabetes
- Birth, Development, and Health
- Genetic and rare skin diseases.
- Acute Lymphoblastic Leukemia research
- Diabetic Foot Ulcer Assessment and Management
- Oropharyngeal Anatomy and Pathologies
- Synthesis of Tetrazole Derivatives
- Obesity and Health Practices
- Bee Products Chemical Analysis
University of Oxford
2025
The Royal Free Hospital
2025
University College London
2025
European Neuroendocrine Tumor Society
2025
Research Institute for Endocrine Sciences
2017-2025
Queen Mary University of London
2025
Shahid Beheshti University
2025
Shahid Beheshti University of Medical Sciences
2017-2024
Kermanshah University of Medical Sciences
2024
Zanjan University of Medical Sciences
2008-2016
Objective: To assess the effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus. Methods: In a double-blinded, placebo-controlled clinical trial, 70 diabetic were enrolled. They allocated randomly into group control group. consumed 1600 mg versus wheat flour placebo daily for 12 weeks. Serum sugar, lipids, CRP, PGE2 TNFα measured before after intervention. Results: Ginger reduced fasting plasma glucose, HbA1C,...
The effects of sex hormones remain largely unexplored in pheochromocytomas and paragangliomas (PPGLs) gastroenteropancreatic neuroendocrine tumors (GEP-NETs). We evaluated the estradiol, progesterone, Dehydroepiandrosterone sulfate (DHEAS), testosterone on human patient-derived PPGL/GEP-NET primary culture cell viability (n = 38/n 12), performed next-generation sequencing immunohistochemical hormone receptor analysis PPGL tumor tissues 36). In PPGLs, estradiol progesterone (1 µm)...
Abstract Objective Heterozygous germline loss-of-function variants in AIP are associated with young-onset growth hormone and/or prolactin-secreting pituitary tumours. However, the pathogenic role of c.911G>A; p.(Arg304Gln) (R304Q) variant has been controversial. Recent data from public exome/genome databases show this is not infrequent. The objective work was to reassess pathogenicity R304Q based on clinical, genomic and functional assay data. Design, materials methods Data were...
Considering recent revisions in the nomenclature for fatty liver disease, alongside limited data on sex-specific differences its cardiovascular/mortality outcomes, this study aims to investigate prevalence and impact of metabolic-associated disease (MAFLD) cardiovascular (CVD) mortality men women over a 12-year follow-up period. In large population-based cohort study, 7101 individuals aged ≥ 30 were enrolled. The MAFLD was investigated both genders. After excluding with history previous CVD,...
Objectives. To examine the efficacy of combination therapy with levothyroxine and liothyronine in improvement general health, psychological problems, metabolic status primary hypothyroidism. Methods. Seventy-one patients diagnosed hypothyroidism were randomly allocated into two study groups: first group received usual dose second for at least 4 months. The main outcomes psychosocial problems (Goldberg's General Health Questionnaire, GHQ-28), bodyweight, heart rate, blood pressure, serum...
Abstract Background Various risk of mortality due to hip fracture has been reported by different studies. There is scarce controlled study on from developing countries and no data Middle East region. The objective this determine its factors one year after low trauma fracture. Methods One hundred two patients not caused high impact injuries or local bone diseases followed up prospectively for year. Control group consisted sex age matched admitted ophthalmology ward eye surgery. Data about...
Gestational diabetes mellitus (GDM) affects nearly 5% of pregnancies. Significant proportion the women with previous GDM develops type 2 (T2DM) in next years, which indicates a higher risk them than general population.We conducted this study to determine factors and incidence abnormal glucose level metabolic syndrome (MetS) history long period after delivery our region.We extracted demographic characteristics 110 who had delivered during 2004 - 2010 three main hospitals Zanjan City, Iran....
Hypovitaminosis D has been associated with the development of gestational diabetes mellitus (GDM) in many observational studies.We report first study impact prenatal vitamin supplementation on postpartum dysglycemia GDM patients a randomized clinical trial.Women at 12 - 32 weeks gestation were assigned randomly to either intervention group (in which serum 25-hydroxy [25OHD] levels measured immediately, n = 48) or control was stored and assayed 6 post-partum, 48). Participants initial 25OHD <...
: Background: In Iran, congenital hypothyroidism (CH) screening programs to prevent mental retardation have been started recently. this national program, all neonates with thyroid-stimulating hormone (TSH) level ≥ 5mIU/L are required be recalled for a confirmatory test (venous sampling).Objectives: This study was designed investigate the incidence of CH and patient recall rate on basis above mentioned cutoff value TSH compare results those obtained in other studies.Patients Methods:...
The aim of this study was to estimate the incidence hip fracture in Zanjan, Iran and describe its seasonal variation. A total 244 cases fractures (131 men, 113 women) were recorded during 1 year. annual age-standardized rates 206.5 214.8 per 100,000 men women, respectively. Most occurred winter, in-house daytime. In-hospital mortality 2.5%. Incidence rate (HF) less than western countries mostly due lower which is probably because breast-feeding. One most important consequences osteoporosis...
Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood. Patients with ALL commonly present easy bruising and infections due to medullary involvement. The extra involvements manifests as hepatosplenomegaly, lymphadenopathy, testicular enlargement. Among extramedullary manifestations ALL, thyroid involvement rare. Herein, we reported a case that manifested nodule.An 18-year-old young man nodule presented without any other symptom or sign. excisional biopsy was planned by...
Cushing's syndrome (CS) is a rare disorder, once exogenous causes have been excluded. However, when diagnosed, the majority of cases are adrenocorticotropic hormone (ACTH)-dependent, which substantial minority due to source outside pituitary, ectopic ACTH (EAS). Differentiating among pituitary-dependent CS, disease (CD) and an can be problematic. Because non-invasive tests in evaluation CS patients often lack adequate sensitivity specificity, bilateral inferior petrosal sinus sampling...