A5001693609- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Facial Nerve Paralysis Treatment and Research
- COVID-19 epidemiological studies
- Ear Surgery and Otitis Media
- Long-Term Effects of COVID-19
- Reconstructive Facial Surgery Techniques
- Trauma Management and Diagnosis
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Diabetes and associated disorders
- Congenital Ear and Nasal Anomalies
- Facial Trauma and Fracture Management
- Olfactory and Sensory Function Studies
- Reconstructive Surgery and Microvascular Techniques
- COVID-19 Pandemic Impacts
- Nasal Surgery and Airway Studies
- Tracheal and airway disorders
- Biochemical Analysis and Sensing Techniques
- vaccines and immunoinformatics approaches
- Phonetics and Phonology Research
- Trigeminal Neuralgia and Treatments
- Facial Rejuvenation and Surgery Techniques
- COVID-19 and healthcare impacts
- Ear and Head Tumors
Centre Hospitalier Universitaire de Nice
2023-2025
Unité de Recherche Clinique Côte d'Azur
2024-2025
Observatoire de la Côte d’Azur
2024-2025
Ministry of Health
2019-2023
Université Côte d'Azur
2023
Centre Antoine Lacassagne
2023
Al-Sabah Hospital
2022
Hôpital de la Conception
2017-2020
Aix-Marseille Université
2018-2019
Assistance Publique Hôpitaux de Marseille
2018
This is a retrospective single-center study of 417 consecutive patients with coronavirus disease 2019 (COVID-19) admitted to Jaber Al-Ahmad Hospital in Kuwait between February 24, 2020 and May 2020. In total, 39.3% were asymptomatic, 41% symptomatic mild/moderate symptoms, 19.7% the intensive care unit (ICU). Most common symptoms cohort fever (34.3%) dry cough (32.6%) while shortness breath was reported (75.6%) ICU admissions. Reported complications requiring admission included Sepsis...
COVID-19 is challenging healthcare preparedness, world economies, and livelihoods. The infection death rates associated with this pandemic are strikingly variable in different countries. To elucidate discrepancy, we analyzed 2431 early spread SARS-CoV-2 sequences from GISAID. We estimated continental-wise admixture proportions, assessed haplotype block estimation, tested for the presence or absence of strains' recombination. Herein, identified 1010 unique missense mutations seven clusters....
COVID-19 has a highly variable clinical presentation, ranging from asymptomatic to severe respiratory symptoms and death. Diabetes seems be one of the main comorbidities contributing worse outcome.In here we analyze characteristics outcomes diabetic patients Kuwait.In this single-center, retrospective study 417 consecutive patients, compare disease severity, outcome, associated complications, laboratory findings between non-diabetic patients.COVID-19 with diabetes had more ICU admission than...
Abstract Objective To evaluate taste disorders after middle ear surgery, their modifying factors especially chorda tympani nerve injury or underlying otologic disease. We investigated consequences of on quality life. Study Design Prospective cohort study. Setting Monocentric study in tertiary care center. Methods A total 214 patients who underwent surgery were included. Data regarding collected by questionnaires over a 1‐year follow‐up period. Results Taste reported 42.7% at 10 days, 23.3% 4...
To translate and validate French versions of two health-related quality life questionnaires for patients with peripheral facial palsy: Facial Disability Index (FDI) Clinimetric Evaluation (FaCE) scale.Prospective cohort study.University tertiary referral centre.A pilot test was performed on 10 subjects (5 palsy more than 1-month duration 5 normal subjects), then 67 adult were enrolled in the validation study.Translation original has followed international guidelines using a forward-backward...
Abstract This is a retrospective single-center study of 417 consecutive patients with coronavirus disease 2019 (COVID-19) admitted to Jaber Al-Ahmad Hospital in Kuwait between February 24, 2020 and May 2020. In total, 39.3% were asymptomatic, 41% symptomatic mild/moderate symptoms, 5.3% the intensive care unit (ICU) recovered, 14.4% died. The mean age death cases was 54.20 years (± 11.09). Comorbidities more prevalent who died compared others. Key findings include abnormal levels markers...
Abstract Background Many countries have succeeded in curbing the outbreak of COVID-19 by employing strict public health control measures. However, little is known about effectiveness such measures developing countries. In this study, we seek to assess impact various Kuwait gain more insight into progression and associated healthcare burden. Methods We use a SEIR mathematical model simulate epidemic with additional testing hospitalization compartments. NBD observational framework for...
Abstract Background The objective of this study was to evaluate the impact early oral hydration on incidence pharyngocutaneous fistula (PCF) after total laryngectomy (TL) or pharyngolaryngectomy (TPL). Methods A prospective series 25 patients operated between October 2017 and March 2019 who received starting 2 days surgery were compared a retrospective cohort 28 did not receive any hydration. These are two consecutive including all patients. Results There no significant difference groups in...
Abstract Background COVID-19 has a highly variable clinical presentation, ranging from asymptomatic to severe respiratory symptoms and death. Diabetes seems be one of the main comorbidities contributing worse outcome. Objective In here we analyze characteristics outcomes diabetic patients Kuwait. Methods this single-center, retrospective study 417 consecutive patients, compare disease severity, outcome, associated complications, laboratory findings between non-diabetic patients. Results with...
Abstract Objectives To investigate the role of ethnicity in COVID-19 outcome disparities a cohort Kuwait. Methods This is retrospective analysis 405 individuals infected with SARS-CoV-2 Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression models used to report odds ratios (OR) for ICU admission dying from COVID-19. Results The included 290 Arabs 115 South Asians. Asians recorded significantly higher death rates compared (33% vs. 7.6%, P...
Background: Many countries have succeeded in curbing the initial outbreak of COVID-19 by imposing strict public health control measures. However, little is known about effectiveness such measures developing countries. In this study, we seek to assess impact various Kuwait gain more insight into progression and associated healthcare burden. Methods: We use a SEIR mathematical model simulate first wave epidemic with additional testing hospitalization compartments. calibrate our using NBD...
Background: Middle ear (ME) pressure regulation has been suggested as a physiological mechanism that maintains equilibrium between the ME and ambient environment. This would be based on complex sensorineural reflex loop composed of mechanoreceptors, an integrative center, efferent neural pathways. Our aim was to demonstrate hypoxic conditions, which inhibit mechanoreceptors in general, similarly participate inhibition opening Eustachian tube (ET), thus, suggest such receptors are involved...
Abstract COVID-19 is challenging healthcare preparedness, world economies, and livelihoods. The infection death rates associated with this pandemic are strikingly variable in different countries. To elucidate discrepancy, we analyzed 2431 early spread SARS-CoV-2 sequences from GISAID. We estimated continental-wise admixture proportions, assessed haplotype block estimation, tested for the presence or absence of strains recombination. Herein, identified 1010 unique missense mutations seven...
Developing countries are struggling to control the COVID-19 outbreak, facing shortage in testing supplies and international competition. Many with relatively smaller populations like Kuwait have resorted early lockdowns aggressive public health interventions. had its first imported case on Feb 24, 2020. Analysis of data from stage outbreak can provide important information about potential epidemic healthcare burdens as well assist evaluating impact various measures. Such measures essentially...