A5103156737- Antibiotic Resistance in Bacteria
- Blood Coagulation and Thrombosis Mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
- Vibrio bacteria research studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Hemophilia Treatment and Research
- Bacterial biofilms and quorum sensing
- Salmonella and Campylobacter epidemiology
- Venous Thromboembolism Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Long-Term Effects of COVID-19
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Caching and Content Delivery
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Antibiotics Pharmacokinetics and Efficacy
- Immunotherapy and Immune Responses
- Viral gastroenteritis research and epidemiology
- Reservoir Engineering and Simulation Methods
- Urinary Tract Infections Management
- Peer-to-Peer Network Technologies
- Recommender Systems and Techniques
- Enterobacteriaceae and Cronobacter Research
- vaccines and immunoinformatics approaches
Kuwait University
2014-2025
Islamic Azad University, Tehran
2015
University of Health and Allied Sciences
2008-2010
Eastman Dental Hospital
2010
University College London
2010
Polytechnique Montréal
2009
The molecular epidemiology and mechanisms of resistance carbapenem-resistant Enterobacteriaceae (CRE) were determined in hospitals the countries Gulf Cooperation Council (GCC), namely, Saudi Arabia, United Arab Emirates, Oman, Qatar, Bahrain, Kuwait. Isolates subjected to PCR-based detection antibiotic-resistant genes repetitive sequence-based PCR (rep-PCR) assessments clonality. Sixty-two isolates which screened positive for potential carbapenemase production assessed, 45 found produce...
The molecular epidemiology and mechanisms of resistance carbapenem-resistant Acinetobacter baumannii (CRAB) were determined in hospitals the states Cooperation Council for Arab States Gulf (Gulf [GCC]), namely, Saudi Arabia, United Emirates, Oman, Qatar, Bahrain, Kuwait. Isolates subjected to PCR-based detection antibiotic genes repetitive sequence-based PCR (rep-PCR) assessments clonality. Selected isolates multilocus sequence typing (MLST). We investigated 117 resistant carbapenem...
Background: The emergence of new COVID-19 variants concern coupled with a global inequity in vaccine access and distribution has prompted many public health authorities to circumvent the shortages by altering vaccination protocols prioritizing persons at high risk. Individuals previous infection may not have been prioritized due existing humoral immunity. Objective: We aimed study association between antibody levels after vaccination. Methods: A serological analysis measure SARS-CoV-2...
This is a retrospective single-center study of 417 consecutive patients with coronavirus disease 2019 (COVID-19) admitted to Jaber Al-Ahmad Hospital in Kuwait between February 24, 2020 and May 2020. In total, 39.3% were asymptomatic, 41% symptomatic mild/moderate symptoms, 19.7% the intensive care unit (ICU). Most common symptoms cohort fever (34.3%) dry cough (32.6%) while shortness breath was reported (75.6%) ICU admissions. Reported complications requiring admission included Sepsis...
The molecular epidemiology and resistance mechanisms of carbapenem-resistant Pseudomonas aeruginosa (CRPA) were determined in hospitals the countries Gulf Cooperation Council (GCC), namely, Saudi Arabia, United Arab Emirates, Oman, Qatar, Bahrain Kuwait.Isolates screened for common carbapenem-resistance genes by PCR. Relatedness between isolates was assessed using previously described genotyping methods: an informative-single nucleotide polymorphism MassARRAY iPLEX assay (iPLEX20SNP)...
COVID-19 has a highly variable clinical presentation, ranging from asymptomatic to severe respiratory symptoms and death. Diabetes seems be one of the main comorbidities contributing worse outcome.In here we analyze characteristics outcomes diabetic patients Kuwait.In this single-center, retrospective study 417 consecutive patients, compare disease severity, outcome, associated complications, laboratory findings between non-diabetic patients.COVID-19 with diabetes had more ICU admission than...
Introduction. Urinary tract infections (UTIs) are associated with a high burden of morbidity, mortality and cost. Pseudomonas aeruginosa employs myriad virulence factors, including biofilm formation motility mechanisms, to cause persistent UTIs. P. is highly resistant antibiotics, the World Health Organization has identified it as pathogen for which novel antimicrobials urgently required. Gap statement. Genotypic phenotypic characterization from UTIs underreported. In addition, rise...
Acinetobacter baumannii is one of the most important opportunistic pathogens that causes serious health care associated complications in critically ill patients. In current study we report on diversity clinical multi-drug resistant A. Kuwait by molecular characterization. One hundred were isolated from largest governmental hospitals Kuwait. Following identification isolates methods, amplified blaOXA-51-like gene product isolate (KO-12) recovered blood showed insertion ISAba19 at position 379...
The present study was undertaken to evaluate the effects of black tea intake on inflammatory cytokines and metabolic biomarkers in Type 2 diabetes mellitus (T2DM). Thirty patients with T2DM were randomly assigned either a High Intake (HI) group, consuming three cups (600 mL) per day; Low (LI) administered 1 cup (200 day, each during 12‐week period. Intracellular cytokine expression, regulatory T cells (Treg), glycemic lipid profiles measured at baseline following Tea consumption correlated...
The objective of this investigation was to identify the lineages MRSA and MSSA with reduced susceptibility chlorhexidine in Kuwaiti hospitals. 121 clinical 56 isolates were included study. Antimicrobial testing performed for a selection agents including resistance genes amplified sequenced. PFGE, spa typing MLST completed isolates. results showed SCCmec II, III, IV V present 0.8%, 21.5%, 69.4% 8.3% agr-1Sa most prevalent type both (48%) (54%). 45% contained pvl 39% lukE-lukD, however, as...
The spread of antibiotic-resistant bacteria has become a large problem in most countries including Kuwait. This antibiotic resistance is usually due to the production extended-spectrum β -lactamase (ESBL) enzymes such as SHV, TEM and CTX-M. study reports emergence an ESBL-producing Klebsiella pneumonia e clone neonatal intensive care unit (NICU) Kuwaiti hospital. Eight K. pneumoniae isolates were from blood cultures seven neonates, two fingers healthcare workers NICU Al Jahra Hospital, All...
Local delivery of antibiotics may provide the advantage reducing potential side effects associated with their systemic administration. This study assessed, in vitro, antimicrobial efficacy tetracycline hydrochloride (TCH) adsorbed onto Bio-Oss bone grafts against a range pathogenic bacteria. Various levels TCH were granules by immersing aqueous solutions different initial concentrations for 48 h at room temperature. release was assessed phosphate buffered saline 37 degrees C, and its...
Type 2 diabetes mellitus (T2DM) features insulin resistance, hyperglycemia, dyslipidemia, overproduction of inflammatory cytokines, and systemic oxidative stress. Here, heat shock proteins Hsp70 Hsp 90, adiponectin, heme oxygenase-1 (HO-1, Hsp32) are profiled in peripheral blood mononuclear cells (PBMC) serum from 25 T2DM patients healthy control subjects. Cells cultured with phorbol 12-myristate 13-acetate/ionomycin were evaluated by three-color flow cytometry for immunophenotypic...
Abstract This is a retrospective single-center study of 417 consecutive patients with coronavirus disease 2019 (COVID-19) admitted to Jaber Al-Ahmad Hospital in Kuwait between February 24, 2020 and May 2020. In total, 39.3% were asymptomatic, 41% symptomatic mild/moderate symptoms, 5.3% the intensive care unit (ICU) recovered, 14.4% died. The mean age death cases was 54.20 years (± 11.09). Comorbidities more prevalent who died compared others. Key findings include abnormal levels markers...
ABSTRACT Blood isolates of Salmonella enterica serovar Typhi from two recently returned Bangladeshi patients in Kuwait were ciprofloxacin resistant, with MICs 12 mg/liter for both isolates. Both had three novel gyrA mutations (55-Leu→Trp, 87-Asp→Ala, and 106-Gln→Arg) parC (84-Glu→Lys, 106-Trp→Gly, 128-Tyr→Asp).
The present study evaluates a hypothesis that sour cherry ( Prunus cerasus ) seed extracts (SCE) modulate CD3+ T lymphocyte activity in ways predictive of potential for uses SCE management inflammatory diseases. Peripheral blood mononuclear cells (PBMC) from 12 type 2 diabetes (T2DM) patients and eight healthy control subjects were cultured 24 h with 100 ng/ml lipopolysaccharide (LPS) to increase signaling co‐incubated 0.5–100 µg/ml SCE. Cultures evaluated by two‐color flow cytometry percent...
In most hospitals, chlorhexidine is used as skin antiseptic prior to clinical procedures, in dressings and when bathing patients. We hereby report, for the first time, isolation of a Klebsiella oxytoca isolate with reduced sensitivity from foot ulcer diabetic patient, which common serious complication associated diabetes. The Minimum Inhibitory Concentration K. was found be 30 mg/L Bactericidal 60 mg/L. An increased resistance ethidium bromide (MIC 200 mg/ L) also observed. Molecular tests...
To develop an effective pharmaceutical treatment for a disease, we need to fully understand the biological behavior of that especially when dealing with cancer. The current available cancer may help in lessening burden disease or, on certain occasions, increasing survival patient. However, total eradication remains researchers hope. Some discoveries field medicine relied observations natural events. Among these events is spontaneous regression It has been argued such could be...