A5057219909- COVID-19 epidemiological studies
- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Vibrio bacteria research studies
- SARS-CoV-2 and COVID-19 Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Antibiotic Use and Resistance
- Salmonella and Campylobacter epidemiology
- Mycobacterium research and diagnosis
- Respiratory viral infections research
- COVID-19 and healthcare impacts
- Infectious Diseases and Tuberculosis
- Enterobacteriaceae and Cronobacter Research
- Bacterial Infections and Vaccines
- Food Safety and Hygiene
- Viral Infections and Outbreaks Research
- Nosocomial Infections in ICU
- Antifungal resistance and susceptibility
- Pharmaceutical and Antibiotic Environmental Impacts
Ministry of Health
2016-2025
The Research Council
2023
National Public Health Laboratory
2021
Ministry of Agriculture and Fisheries
2021
Royal Hospital
2010-2020
The molecular epidemiology and mechanisms of resistance carbapenem-resistant Enterobacteriaceae (CRE) were determined in hospitals the countries Gulf Cooperation Council (GCC), namely, Saudi Arabia, United Arab Emirates, Oman, Qatar, Bahrain, Kuwait. Isolates subjected to PCR-based detection antibiotic-resistant genes repetitive sequence-based PCR (rep-PCR) assessments clonality. Sixty-two isolates which screened positive for potential carbapenemase production assessed, 45 found produce...
The molecular epidemiology and mechanisms of resistance carbapenem-resistant Acinetobacter baumannii (CRAB) were determined in hospitals the states Cooperation Council for Arab States Gulf (Gulf [GCC]), namely, Saudi Arabia, United Emirates, Oman, Qatar, Bahrain, Kuwait. Isolates subjected to PCR-based detection antibiotic genes repetitive sequence-based PCR (rep-PCR) assessments clonality. Selected isolates multilocus sequence typing (MLST). We investigated 117 resistant carbapenem...
To establish the role of local transmission versus possible pathogen import due to previous foreign exposure in infections caused by carbapenem non-susceptible Enterobacteriaceae Arabian Peninsula, 200 independent isolates collected 16 hospitals Saudi Arabia, Kuwait, Oman and United Arab Emirates were studied. All strains multidrug resistant; 42.5% them also qualified as extremely drug resistant. The frequency various carbapenemases varied according participating countries, but collection, a...
Candida auris has emerged in the past decade as a multi-drug resistant public health threat causing care outbreaks. Here we report epidemiological, clinical, and microbiological investigations of C. outbreak regional Omani hospital between April 2018 2019. The started intensive areas (intensive unit (ICU), coronary (CCU), high dependency unit) but cases were subsequently diagnosed other medical surgical units. In addition to patients' clinical screening samples, environmental swabs from...
The molecular epidemiology and resistance mechanisms of carbapenem-resistant Pseudomonas aeruginosa (CRPA) were determined in hospitals the countries Gulf Cooperation Council (GCC), namely, Saudi Arabia, United Arab Emirates, Oman, Qatar, Bahrain Kuwait.Isolates screened for common carbapenem-resistance genes by PCR. Relatedness between isolates was assessed using previously described genotyping methods: an informative-single nucleotide polymorphism MassARRAY iPLEX assay (iPLEX20SNP)...
AimThe purpose of this viewpoint is to summarize the advantages and constraints tools strategies available for reducing annual incidence tuberculosis (TB) by implementing World Health Organization (WHO) End TB Strategy linked WHO Elimination Framework, with special reference Oman.MethodsThe case-study was built based on presentations discussions at an international workshop elimination in low countries organized Ministry Health, Oman, which took place from September 5 7, 2019, supported...
Background: Candida auris (C. auris) is an emerging healthcare-associated pathogen resulting in significant morbidity and mortality. The aim of this study to report data from the national C. surveillance system for 2019 conduct a survival analysis reported cohort. Methods: retrospective was conducted all cases nationally Oman Antimicrobial Surveillance System (OMASS) 2019, isolates were sent Central Public Health Laboratories (CPHL). Clinical demographic obtained through E-Surveillance...
PulseNet International (PNI) is a global network of 88 countries who work together through their regional and national public health laboratories to track foodborne disease around the world. The vision PNI implement globally standardized surveillance using whole genome sequencing (WGS) for real-time identification subtyping pathogens strengthen preparedness response lower burden disease. Several in North America Europe have experienced significant benefits mitigation after implementing WGS....
Hypervirulent Klebsiella pneumoniae (hvKp) is a variant that has been increasingly linked to severe, life-threatening infections including pyogenic liver abscess and bloodstream infections. HvKps belonging the capsular serotypes K1 K2 have reported worldwide, however, very scarce studies are available on their genomics virulence. In current study, we report four hypermucoviscous extended-spectrum β-lactamase-producing hvKp clinical strains of serotype isolated from pus urine critically ill...
Background: Since the introduction of vaccination in Oman 1981, measles incidence has decreased, and achieved elimination 2019. Measles cases country are currently import-related. Aim: To understand immunity profile Omani population identify high-risk groups. Methods: A total 1990 anonymous blood samples out 2032 collected from all regional referral hospitals one private laboratory November 2015 to January 2016 were tested for immunoglobulin G. We grouped study into 4 birth cohorts analysed...
Background: Since the introduction of vaccination in Oman 1981, measles incidence has decreased, and achieved elimination 2019. Measles cases country are currently import-related. Aim: To understand immunity profile Omani population identify high-risk groups. Methods: A total 1990 anonymous blood samples out 2032 collected from all regional referral hospitals one private laboratory November 2015 to January 2016 were tested for immunoglobulin G. We grouped study into 4 birth cohorts analysed...
Crimean-Congo hemorrhagic fever (CCHF) is a serious disease with high fatality rate reported in many countries. The first case of CCHF Oman was detected 1995 and serosurveys have suggested widespread infection humans livestock throughout the country.Cases to Ministry Health (MoH) between 2017 were retrospectively reviewed. Diagnosis confirmed by serology and/or molecular tests Oman. Stored RNA from recent cases studied sequencing complete open reading frame (ORF) viral S segment at Public...
The purpose of this study was to characterize the New Delhi metallo-beta lactamase (NDM)-7-producing Enterobacteriaceae isolated in Arabian Peninsula.Enterobacteriaceae identified carry blaNDM-7 a collection 157 NDM-producing isolates from Kuwait, Oman, Saudi Arabia, and United Arab Emirates (UAE) were investigated for their antibiotic disinfectant susceptibility, resistance gene content. virulence profile, phylogenetic sequence types also determined. plasmids carrying transferred, complete...
BackgroundCOVID-19's emergence carries with it many uncertainties and challenges, including strategies to manage the epidemic. Oman has implemented non-pharmaceutical interventions (NPIs) mitigate impact of COVID-19. However, responses NPIs may be different across populations within a country large number migrants, such as Oman. This study investigated NPIs, assessed use time-varying reproduction (Rt) monitor them.MethodsPolymerase chain reaction (PCR) laboratory-confirmed COVID-19 data for...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been proven to be lethal human health, which affects almost every corner of the world. The objectives this study were add context global data and international genomic consortiums, give insight into efficiency contact tracing system in Oman.We combined epidemiological whole-genome sequence from 94 samples SARS-CoV-2 Oman understand origins, genetic variation, transmissibility. size was obtained through a customized SARS-COV-2...
To assess the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Oman and longitudinal changes antibody levels over time within first 11 months coronavirus disease 2019 (COVID-19) pandemic.This nationwide cross-sectional study was conducted as a four-cycle serosurvey using multi-stage stratified sampling method from July to November 2020. A questionnaire used included demographics, history infection list symptoms, COVID-19 contact, previous diagnosis or...
Background Influenza is a serious vaccine‐preventable disease with high incidence, hospitalization, and mortality in high‐risk groups. The epidemiology, seasonality, risk factors for influenza are well defined most of the temperate countries, but estimating burden World Health Organization (WHO) Region Eastern Mediterranean scarce. In Oman, despite advancements surveillance, clinical seasonality remain not fully understood. Objectives To estimate incidence influenza‐associated...
The prevalence of carbapenem-resistant Enterobacterales (CRE) in the Arabian Peninsula is predicted to be high, as suggested from published case reports. Of particular concern, E. coli (CR-EC), due importance this species a community pathogen. Herein, we conducted comprehensive molecular characterization putative CR-EC strains Oman. We aim establish baseline for future monitoring. performed whole-genome sequencing (WGS) 35 CR-EC. Isolates were obtained patients at multiple centers 2015....
Mycobacterium tuberculosis (MTB) is a global public health issue. Although Oman reduced the burden of (TB) by 85% in under 25 years, annual incidence rate remains stagnant. Whole genome sequencing (WGS) used to investigate transmission dynamics MTB complex. This study aimed resolve traditional genotype clusters and exploring geospatial distribution understand epidemiology TB Oman.Confirmed cases with spoligotyping were randomly selected. WGS 70 isolates selected for final analysis....
Abstract Introduction Severe acute respiratory illness (SARI) is a potentially lethal condition, necessitating thorough medical care. COVID‐19 underscored the SARI threat, but other high‐risk pathogens require monitoring alongside SARS‐CoV‐2. Oman instituted comprehensive testing system to gauge prevalence of these between 2017 and 2021, aiding resource allocation public health responses potential pathogen outbreaks. Methods Samples from cases admitted ICU were tested for using Fast‐Track...
Mucormycosis is a rare, severe fungal infection mainly affecting immunocompromised individuals. Because of limited data on its epidemiology in Oman, we present this national, multicentric, retrospective review that includes all cases proven mucormycosis between 2006 and 2022 Oman. There were 51 reported The annual incidence was 0.38-0.69 per million population before COVID-19. During the pandemic, rose significantly to 1.76 2020, 5.31 2021, then decreased 0.87 2022. Diabetes observed 82.4% (