Serum specimens from 163 persons with Lyme disease, tick-borne or louse-borne relapsing fever, yaws, syphilis, leptospirosis, Rocky Mountain spotted fever were analyzed to assess the specificity of indirect fluorescent antibody (IFA) tests, an enzyme-linked immunosorbent assay (ELISA), and microscopic agglutination (MA) procedures. Strong cross-reactivity occurred when sera individuals tested against heterologous Borrelia antigens. Antibodies burgdorferi bound Treponema pallidum in...

An enzyme-linked immunosorbent assay was compared with an indirect fluorescent antibody test for its ability to detect antibodies the Lyme disease spirochete in sera of naturally infected humans, dogs, and white-footed mice experimentally Swiss mice. Ninety-five percent total 123 analyzed reacted similarly both tests. For 36 human sera, correlation coefficient (r = 0.47) logarithmic transformations titers significant at P less than 0.01. Within each mammalian species, mean were within...

This study aimed to examine attention and processing speed outcomes in very preterm (VPT; < 32 weeks' gestational age) or low birth weight (VLBW; 1,500 g) children, determine whether brain abnormality measured by neonatal MRI can be used predict outcome these domains.

Results of hospital-based studies indicate a high risk cognitive impairment 3 months after stroke. There are no comprehensive data on this issue from prospective community-based comparing first-ever stroke patients with stroke-free subjects.We administered neuropsychological battery to 99 nonaphasic survivors at and age- sex-matched (1:1) individuals. Domain-specific deficits were identified by blinded consensus.Stroke more likely suffer any (relative [RR], 1.5; 95% CI, 1.1 2.1) attributable...

Journal Article Transovarlal Transmission of Borrelia burgdorferi in Ixodes dammini (Acari:Ixodidae) Get access Louis A. Magnarelli, Magnarelli Department Entomology, the Connecticut Agricultural Experiment Station, New Haven, Connecticut; and Medical Entomology Laboratory, York College, Armonk, Please address requests for reprints to Dr. P. O. Box 1106,New 06504. Search other works by this author on: Oxford Academic PubMed Google Scholar John F. Anderson, Anderson Durland Fish The...

Borrelia burgdorferi, the etiologic agent of Lyme disease, was isolated from 111 237 Peromyscus leucopus captured during all seasons year. Borreliae were cultured tissues spleen (101 mice), left kidney (76 and right (73 blood (12 one fetus. Mice infected winter, when immature Ixodes dammini inactive. The prevalence infection winter (less than or equal to 33%) more twofold lower that summer (ca. 75%), a time nymphal ticks are abundant. Overwintering, mice reservoir hosts for subadult begin...

Primary objective: To determine whether neuropsychological test performance or affective factors predict long-term post-concussive symptoms and cognitive complaint following mild traumatic brain injury.Methods procedures: Participants included 21 individuals with injury, 19 spinal injury but no to the 20 neurologically-normal controls. All participants completed measures of symptoms, complaint, depression, anxiety, personality were administered a variety tests.Main outcomes results: The...

Borrelia burgdorferi, the etiologic agent of Lyme disease, and Babesia microti, causative human babesiosis, were isolated from 71 57%, respectively, 14 specimens Peromyscus leucopus Microtus pennsylvanicus collected Prudence Patience Islands, R.I. Both pathogens five individual rodents. The presence these two infectious organisms in same mammal suggests that larval Ixodes dammini may ingest both subsequently transmit them nymphal stage.

Borrelia burgdorferi and Babesia microti were isolated from 35 of 51 white-footed mice (Peromyscus leucopus) meadow voles (Microtus pennsylvanicus) captured on two Narragansett Bay, R.I., islands inhabited by deer, the principal host for adult stages vector tick, Ixodes dammini. Immature ticks parasitized both islands. From 105 four other not deer neither pathogen was isolated, nor I. dammini found.

Depression after a traumatic brain injury (TBI) is very common, yet there lack of evidence-based treatment options for people who experience depression TBI. Traditionally, history TBI has been considered an exclusion criterion transcranial magnetic stimulation trials because the increased risk seizure We present what we believe to be first case patient with treated stimulation.

In prior research, older adults were found to be less responsive social slights than younger adults, but the mechanisms behind such effects have remained unclear. The present study examined age differences in susceptibility deleterious of exclusion and investigated explanatory role cognitive socioemotional variables. Forty (aged 22–39) 40 58–89) played a modified version "Cyberball," virtual ball-tossing game, which they initially included by 2 other players progressively excluded subsequent...

The clinical differentiation of progressive supranuclear palsy from P arkinson's disease can be challenging, due to overlapping features and a lack diagnostic markers. Abnormalities in cognitive function form part the spectrums these diseases distinctive profiles may helpful differentiating period. A comprehensive neuropsychological test battery was administered 12 patients with clinically diagnosed matched for age duration. Effect size ( C ohen's d ) calculated tests that were significantly...

Primary Objective:The most widely used proxies of cognitive complaint after mTBI are post-concussion syndrome (PCS) symptom checklists, which do not have a clear relationship with cognition. This study investigated whether an mTBI-specific measure would clearer associations objective cognition than PCS checklist.Research Design:An observational design was used. A sample 109 participants (52 and 57 healthy controls) completed checklist, measure, measures information processing speed,...

The objective of this study was to determine whether different isolates Babesia microti could be distinguished from morphologically similar B. gibsoni by using a ribosomal DNA (rDNA) probe. A Babesia-specific rDNA probe obtained polymerase chain reaction amplification sequences universal primers directed against highly conserved portions the eukaryotic 16S-like rRNA gene. chemiluminescent hybridized Southern blots restriction endonuclease-digested preparations infected dogs and humans...

Seven cultures of Borrelia burgdorferi differing from strains B31 and ZS7 were identified among 99 isolates Ixodes scapularis ticks white-footed mice (Peromyscus leucopus) 1 isolate an dentatus tick. Five the six novel I. feeding on humans. The lacked OspA OspB, four possessed OspD band, two reacted with anti-OspC monoclonal antibody. Restriction fragment length polymorphisms HindIII-digested DNAs OspA-negative did not hybridize radiolabeled ospA or LA88 DNA, only 46047 hybridized pG gene....

Of 411 forest birds of 33 species examined near Valtice, Czech Republic, 29% were infested with Ixodes ricinus (L.); 2.2% parasitized by Haemaphysalis concinna Koch. Borreliae detected in 5.1 and 11.7% larval nymphal I. ricinus, respectively. None the 13 H. tested was infected. In total, 3.2% immatures infected borreliae. Borreliae-containing ticks European robin, Erithacus rubecula Eurasian blackbird, Turdus merula L.; Blackcap, Sylvia atricapilla chiffchaff, Phylloscopus collybita...

This study investigated whether coping style and/or illness perceptions are related to the severity of self-reported post-concussion syndrome (PCS) symptoms in post-acute period after mild traumatic brain injury (mTBI). We hypothesised that reporting early and late enduring-type PCS symptomatology (self-reported symptoms) would be significantly negatively associated with: (a) an active "approach" (b) belief have negative consequences on respondent's life. Using a prospective observational...