A5060819370- Genomics, phytochemicals, and oxidative stress
- Helicobacter pylori-related gastroenterology studies
- Ion Channels and Receptors
- Nanoplatforms for cancer theranostics
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- HER2/EGFR in Cancer Research
- Advanced Breast Cancer Therapies
- Photodynamic Therapy Research Studies
- Lung Cancer Treatments and Mutations
- Curcumin's Biomedical Applications
- Inhalation and Respiratory Drug Delivery
- Stellar, planetary, and galactic studies
- Building Energy and Comfort Optimization
- Luminescence Properties of Advanced Materials
- Cardiac and Coronary Surgery Techniques
- Ultrasound and Hyperthermia Applications
- Flavonoids in Medical Research
- Nanoparticle-Based Drug Delivery
- Surgical Simulation and Training
- Diet, Metabolism, and Disease
- Inertial Sensor and Navigation
- Wind and Air Flow Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiac, Anesthesia and Surgical Outcomes
- Urban Heat Island Mitigation
Tianjin University
2023-2025
Stone Clinic
2021
Excessive drinking poses serious health risks and is closely associated with oxidative damage. The KEAP1-NRF2-ARE axis serves as the primary antioxidant system. However, existing small molecule inhibitors are all covalently bound to KEAP1, meaning that once bound, they not easily dissociated, while continuous inhibition of KEAP1 exhibits severe side effects. In this study, BLI, CETSA, Pull-down, Co-IP HDX-MS assay analysis were conducted detect binding behavior natural product, capsaicin...
Excessive drinking poses serious health risks and is closely associated with oxidative damage. The KEAP1-NRF2-ARE axis serves as the primary antioxidant system. However, existing small molecule inhibitors are all covalently bound to KEAP1, meaning that once bound, they not easily dissociated, while continuous inhibition of KEAP1 exhibits severe side effects. In this study, BLI, CETSA, Pull-down, Co-IP HDX-MS assay analysis were conducted detect binding behavior natural product, capsaicin...
Ultrasound-enabled nanomedicine leverages ultrasound to amplify the capabilities of engineered nanosystems, paving way for innovative diagnostic and therapeutic breakthroughs in conventional nanomedicine. As a burgeoning discipline, past overviews have sometimes offered fragmented perspective, lacking comprehensive view. This review presents systematic exploration latest advancements ultrasound-enabled nanomedicine, with particular emphasis on oncology. Covered topics include molecular...
Aim: This study aimed to develop a sonodynamic–chemodynamic nanoparticle functioning on glutathione depletion in tumor immunotherapy. Materials & methods: The liposome-encapsulated 2,2-azobis[2-(2-imidazolin-2-yl) propane] dihydrochloride (AIPH) and copper–cysteine nanoparticles, AIPH/Cu-Cys@Lipo, were synthesized with one-pot method. 4T1 cells injected into female BALB/c mice for modeling. Results: AIPH/Cu-Cys@Lipo was well synthesized. It generated alkyl radicals upon ultrasound...
Escalating global climate change and the intensification of urban heatwaves have led to an increase in summer air conditioning cooling energy consumption. This phenomenon is particularly critical tropical regions, as it may trigger crisis. The rational setting indoor thermal design parameters can help conserve maximum extent while ensuring comfort for occupants. study selected Haikou City, a unique city China, research location. Indoor environment measurements questionnaire survey were...
Excessive drinking poses serious health risks and is closely associated with oxidative damage. The KEAP1-NRF2-ARE axis serves as the primary antioxidant system. However, existing small molecule inhibitors are all covalently bound to KEAP1, meaning that once bound, they not easily dissociated, while continuous inhibition of KEAP1 exhibits severe side effects. In this study, BLI, CETSA, Pull-down, Co-IP HDX-MS assay analysis were conducted detect binding behavior natural product, capsaicin...
Excessive drinking poses serious health risks and is closely associated with oxidative damage. The KEAP1-NRF2-ARE axis serves as the primary antioxidant system. However, existing small molecule inhibitors are all covalently bound to KEAP1, meaning that once bound, they not easily dissociated, while continuous inhibition of KEAP1 exhibits severe side effects. In this study, BLI, CETSA, Pull-down, Co-IP HDX-MS assay analysis were conducted detect binding behavior natural product, capsaicin...