- Advancements in Battery Materials
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Advanced Battery Materials and Technologies
- Supercapacitor Materials and Fabrication
- Advanced Battery Technologies Research
- biodegradable polymer synthesis and properties
- Advanced battery technologies research
- Cutaneous Melanoma Detection and Management
- Integrated Circuits and Semiconductor Failure Analysis
- Antimicrobial agents and applications
- Intensive Care Unit Cognitive Disorders
- Music Therapy and Health
- Biosensors and Analytical Detection
- Electrohydrodynamics and Fluid Dynamics
- Osteoarthritis Treatment and Mechanisms
- Nanoparticles: synthesis and applications
- Musculoskeletal synovial abnormalities and treatments
- Neuroscience and Music Perception
- High Entropy Alloys Studies
- Electrospun Nanofibers in Biomedical Applications
- Antimicrobial Peptides and Activities
- Nanopore and Nanochannel Transport Studies
- Thermal Expansion and Ionic Conductivity
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Jinan University
2022-2024
Weatherford College
2023
Reef Ecologic
2023
Fuzhou Second Hospital
2016-2020
Xiamen University
2016-2020
Fujian Medical University
2020
Shanghai Ninth People's Hospital
2014-2016
Shanghai Jiao Tong University
2014-2016
In this study, a nanocalcium silicate (n-CS)/polyetheretherketone (PEEK) bioactive composite was prepared using process of compounding and injection-molding. The mechanical properties, hydrophilicity, in vitro bioactivity the composite, as well cellular responses MC3T3-E1 cells (attachment, proliferation, spreading, differentiation) to were investigated. results showed that properties hydrophilicity composites significantly improved by addition n-CS PEEK. addition, an apatite-layer formed on...
Abstract: A bioactive composite was prepared by incorporating 40 wt% nano-hydroxyapatite (nHA) into polyetheretherketone (PEEK) through a process of compounding, injection, and molding. The mechanical surface properties the nHA/PEEK were characterized, in vitro osteoblast functions investigated. (elastic modulus compressive strength) increased significantly, while tensile strength decreased slightly as compared with PEEK. Further, addition nHA PEEK roughness hydrophilicity composite. In...
Abstract Infection is one of the major causes failure orthopedic implants. Our previous study demonstrated that nanotube modification implant surface, together with nanotubes loaded quaternized chitosan (hydroxypropyltrimethyl ammonium chloride chitosan, HACC), could effectively inhibit bacterial adherence and biofilm formation in vitro. Therefore, aim this was to further investigate vitro cytocompatibility osteogenic cells vivo anti-infection activity titanium implants HACC-loaded (NT-H)....
Abstract: Titania nanotubes loaded with antibiotics can deliver a high concentration of locally at specific site, thereby providing promising strategy to prevent implant-associated infections. In this study we have fabricated titania various diameters (80, 120, 160, and 200 nm) nm length via electrochemical anodization. These were 2 mg gentamicin using lyophilization method vacuum drying. A standard strain, Staphylococcus epidermidis (American Type Culture Collection 35984), two clinical...
The potential threat that silver nanoparticles (Ag NPs) pose to bacterial communities in estuarine environments has become a subject of intensifying global interest. Herein, eight water samples were collected from...
Titanium-based implants have been widely used in orthopedic surgery; however, failures still occur. Our vitro study has demonstrated that gentamicin-loaded, 80 nm-diameter nanotubes possessed both antibacterial and osteogenic activities. Thus, the aim of this was to further investigate vivo anti-infection effect titanium with gentamicin-loaded nanotubes. Thirty-six male Sprague Dawley rats were establish an implant-associated infection model. A volume 50 μL Staphylococcus aureus suspension...
ABSTRACT Infection of open tibial fractures with contamination remains a challenge for orthopedic surgeons. Local use antibiotic-impregnated polymethylmethacrylate (PMMA) beads and blocks is widely used procedure to reduce the risk infection. However, development antibiotic-resistant organisms make management infection more difficult. Our in vitro study demonstrated that quaternized chitosan (hydroxypropyltrimethyl ammonium chloride [HACC])-loaded PMMA bone cement exhibits strong...
Titania nanotube-based local drug delivery is an attractive strategy for combating implant-associated infection. In our previous study, we demonstrated that the gentamicin-loaded nanotubes could dramatically inhibit bacterial adhesion and biofilm formation on implant surfaces. Considering overuse of antibiotics may lead to evolution antibiotic-resistant bacteria, synthesized a new quaternized chitosan derivative (hydroxypropyltrimethyl ammonium chloride chitosan, HACC) with 27% degree...
Realizing the high energy density of lithium batteries depends significantly on creating an electrolyte suited for high-voltage operation and compatible with metal. Generally, a concentration solvents within diluted electrolytes may readily form thick susceptible solid interphases, especially when encountering lithium-metal anode. Herein, we present design by increasing LiTFSI salt dimethyl carbonate (DMC) solvent to solve interfacial incompatibility. The increased not only leads ion...
Delivery of local drugs with a titania nanotube is an attractive approach to combat implant-related infection. Our earlier study has confirmed that nanotubes loaded gentamicin could significantly improve the antibacterial ability. On this basis, used andrographolide in paper high activity, which cannot only avoid evolution antibiotic-resistant bacteria but also simultaneously excellent biocompatibility osteogenic cells.Two mg was into nanotubes, were fabricated different diameters (50 and...
<title>Abstract</title> <bold>Background: </bold>Lower extremity nodular melanoma (NM) is a common malignant tumor with poor prognosis. We aims to identify the prognostic factors and develop nomogram model predict overall survival (OS) in patients lower NM. <bold>Method</bold>: A total of 746 NM were selected randomly divided into training set (522 cases) validation (224 from Surveillance, Epidemiology, End Results(SEER) database. The underwent univariate multivariate Cox regression analyses...