A5100985129- Platelet Disorders and Treatments
- Advanced MRI Techniques and Applications
- Oral microbiology and periodontitis research
- Cancer-related Molecular Pathways
- Functional Brain Connectivity Studies
- Blood groups and transfusion
- Immune cells in cancer
- MicroRNA in disease regulation
- RNA modifications and cancer
- Oral Health Pathology and Treatment
- Neural dynamics and brain function
- Cancer-related molecular mechanisms research
- Protein Degradation and Inhibitors
- Treatment of Major Depression
- Complement system in diseases
- Trace Elements in Health
- Multiple Myeloma Research and Treatments
- Lung Cancer Treatments and Mutations
- Mitochondrial Function and Pathology
- Cancer therapeutics and mechanisms
- Blood properties and coagulation
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- TGF-β signaling in diseases
- Chronic Lymphocytic Leukemia Research
- Hematopoietic Stem Cell Transplantation
Zhejiang University
2024
Hangzhou Seventh Peoples Hospital
2023-2024
China Medical University
2023
Qilu Hospital of Shandong University
2016-2018
Shandong University
2013
Studies in murine models suggested that platelet desialylation was an important mechanism of thrombocytopenia during sepsis. First, we performed a prospective, multicenter, observational study enrolled septic patients with or without to determine the association between and sepsis, severe shock. Gender- age-matched healthy adults were selected as normal controls analysis levels (study I). Next, conducted open-label randomized controlled trial (RCT) which who had sepsis (platelet counts ≤50 ×...
Abstract Porphyromonas gingivalis ( P. ) is a pivotal pathogen of periodontitis. Our previous studies have confirmed that mitochondrial dysfunction in the endothelial cells caused by was dependent on Drp1, which may be mechanism causing dysfunction. Nevertheless, signalling pathway induced remains unclear. The purpose this study to investigate role RhoA/ROCK1 regulating . used infect EA.hy926 (endothelial cells). expression and activation RhoA ROCK1 were assessed western blotting pull‐down...
Selective serotonin reuptake inhibitors (SSRIs) are among the most important antidepressants. However, there is limited research on predicting occurrence of treatment-resistant depression (TRD) after 5 years. Examining predictive effect TRD using resting-state fMRI in patients initiating SSRIs treatment at onset major depressive disorder (MDD) could potentially enhance management.
// Yuan-xin Sun 1 , Hui Li 2 Qi Feng Xin Ying-yi Yu Li-wei Zhou Yan Gao Guo-sheng 3 Juan Ren 4 Chun-hong Ma 5 Cheng-jiang Jun Peng 1, 6 Department of Hematology, Qilu Hospital, Shandong University, Jinan, China Rheumatology, People’s Hospital Bao’an, Shenzhen, Provincial Key Laboratory Immunohematology, First Affiliated Xi’an Jiaotong Xi’an, Immunology, University School Medicine, Cardiovascular Remodeling and Function Research, Chinese Ministry Education Health,...
The aim of this study was to identify regions with altered degrees centrality (DC) and changes in their functional connectivity (FC) first-episode drug-naïve major depressive disorder (FEDN-MDD) patients using resting-state magnetic resonance imaging (fMRI). included 74 FEDN-MDD who met the criteria 41 healthy controls (HCs). All had undergone fMRI scanning resting condition. To evaluate differences between HCs, we first compared DC 2 groups. most significant were then taken as seeds, FC...