A5100353925- Pregnancy and preeclampsia studies
- Minimally Invasive Surgical Techniques
- Uterine Myomas and Treatments
- Platelet Disorders and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ectopic Pregnancy Diagnosis and Management
- Birth, Development, and Health
- Orthopedic Infections and Treatments
- Maternal and fetal healthcare
- Cerebrospinal fluid and hydrocephalus
- Adrenal and Paraganglionic Tumors
- Gestational Diabetes Research and Management
- Blood groups and transfusion
- Orthopaedic implants and arthroplasty
- Thyroid Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Endometriosis Research and Treatment
- Congenital Diaphragmatic Hernia Studies
- Pancreatitis Pathology and Treatment
- Electrospun Nanofibers in Biomedical Applications
- Lung Cancer Treatments and Mutations
- Fetal and Pediatric Neurological Disorders
- Neonatal Respiratory Health Research
- Gestational Trophoblastic Disease Studies
- Gynecological conditions and treatments
University of Electronic Science and Technology of China
2009-2025
Chengdu Women's and Children's Central Hospital
2021-2025
Sichuan University
2023-2025
Central South University
2006-2025
Third Xiangya Hospital
2006-2025
West China Second University Hospital of Sichuan University
2023-2025
Shanghai First People's Hospital
2023-2025
Chinese PLA General Hospital
2016-2024
University of Bern
2021-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2012-2024
Leptomeninges, consisting of the pia mater and arachnoid, form a connective tissue investment barrier enclosure brain. The exact nature leptomeningeal cells has long been debated. In this study, we identify five molecularly distinct fibroblast-like transcriptomes in cerebral leptomeninges; link them to anatomically cell types pia, inner outer arachnoid barrier, dural border layer; contrast sixth transcriptome present choroid plexus median eminence. Newly identified transcriptional markers...
Women with polycystic ovary syndrome (PCOS) have hyperandrogenism and insulin resistance a high risk of miscarriage during pregnancy. Similarly, in rats, maternal exposure to 5α-dihydrotestosterone (DHT) from gestational day 7.5 13.5 leads subsequently increased fetal loss. A variety hormonal metabolic stimuli are able trigger different types regulated cell death under physiological pathological conditions. These include ferroptosis, apoptosis necroptosis. We hypothesized that,...
Introduction Cholangiocarcinoma (CCA) is a malignant tumor of the biliary epithelium with poor prognosis. The lack biomarkers to predict therapeutic response and prognosis one major challenges for CCA treatment. Tertiary lymphoid structures (TLS) provide local pivotal microenvironment immune responses. prognostic value clinical relevance TLS in remain unclear. We aimed explore characteristics significance CCA. Methods investigated using surgery cohort containing 471 patients (cohort 1) an...
Objectives To estimate the prevalence of mild cognitive impairment ( MCI ) in Beijing, China, and to explore potential protective risk factors for . Design Population‐based survey. Setting The Beijing Ageing Brain Rejuvenation Initiative BABRI ). Participants randomly recruited from (N = 1,211). Measurements underwent a battery neuropsychological examinations determine function answered series personal questions. its subtypes were computed using Petersen's criteria. Influencing estimated...
Strong and biodegradable materials are key to the development of next-generation medical devices for interventional treatment. Biodegradable polymers such as polylactide (PLA) have controllable degradation profiles, but their mechanical strength is much weaker than some metallic iron; on other hand, tuning corrosion rate iron a proper time range biomedical applications has always been challenge. Very recently, we achieved complete stent in vivo within clinically required frame by combining...
Detection of in vivo biodegradation is critical for development next-generation medical devices such as bioresorbable stents or scaffolds (BRSs). In particular, it urgent to establish a nondestructive approach examine degradation new-generation coronary stent interventional treatment based on mammal experiments; otherwise not available semi-quantitatively monitor any clinical trial. Herein, we put forward semi-quantitative measure sirolimus-eluting iron scaffold (IBS) optical coherence...
ObjectiveWe aimed to determine the safety of Vaginal natural orifice transluminal endoscopic surgery (vNOTES) in terms Enhanced Recovery after Surgery (ERAS) concept for tubal pregnancy and provide a detailed process vNOTES surgery, including experience key points surgeons performing this procedure.MethodsThe Longitudinal Natural Orifice Transluminal Endoscopic Study (LovNOTESS), which was conducted Chengdu, China. A total 219 patients who underwent ectopic between September 2021 March 2022....
To evaluate the association between body iron stores, dietary intake, and risk of diabetes in northern China.The data a cross-sectional household survey 2002 Liaoning Province China was used. The final sample our study contained 2,997 subjects aged >or=18 years. Fasting plasma glucose serum ferritin were measured. Dietary information collected by 3-day food records.Serum associated with elevated even adjusted for age, sex, nondietary factors, factors. No among total nonheme found. However,...
Type 2 diabetes mellitus (T2DM) results from insulin resistance and β-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which secreted pancreatic α cells: excessively high circulating levels glucagon lead to excessive hepatic glucose output. We investigated if α-cell numbers increase T2DM what factor (s) regulate turnover. Leprdb/Leprdb (db/db) mice were used as model αTC1 cells study potential trophic factors. Here, we demonstrate that db/db...
The anatomical routes for the clearance of cerebrospinal fluid (CSF) remain incompletely understood. However, recent evidence has given strong support leading to lymphatic vessels. A current debate centers upon through which CSF can access lymphatics, with emerging either direct meningeal lymphatics or along cranial nerves reach outside skull. Here, a method was established infuse contrast agent into ventricles using indwelling cannulae during imaging mice at 2 and 12 months age by magnetic...
Advanced maternal age (AMA) pregnancy is associated with higher risks of adverse perinatal outcomes, which may result from premature senescence the placenta. α-Klotho a well-known antiaging protein; however, its expression and effect on placenta in AMA pregnancies have not yet been fully elucidated. The patterns mouse human placentas were determined by Western blotting immunohistochemistry (IHC) staining. JAR cells was manipulated to investigate role trophoblastic senescence, transwell...
ObjectiveThis study aimed to assess the surgical outcomes and identify conversion risk factors of Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) in treating ovarian cyst.MethodsThis was a retrospective 505 patients who underwent vNO TES for cyst from March 2019 February 2022 wherein were classified into "converted" or "nonconverted" groups. T-tests, χ2 tests, logistic regression used statistical analyses.ResultsThere 16 (3.17%) conversions 12 (2.38%) other...
Abstract This is a prospective observational study designed to develop an echocardiography‐guided tip location program for central venous catheter (CVC) implantation, and assess the feasibility accuracy of program. First, multidisciplinary expert committee program; then, pilot was conducted in vascular access clinic tertiary hospital. A total 186 patients participated study. Successful placement achieved 172 (92.5%) patients. The reached 99.4%. feasible accurate. Ultrasound images revealed...
This study aimed to identify risk factors for peripartum hysterectomy among pregnancies complicated by suspected Placenta Accreta Spectrum (PAS) in preoperative obstetric imaging screening. Data were retrospectively extracted from the Longitudinal Study (LoPASS), covering with PAS January 2018 March 2023 at our institute. Patients divided into Control and Hysterectomy groups based on whether they underwent hysterectomy. Sociodemographic, obstetric, clinical characteristics compared between...
Neuroinflammatory processes are directly involved in the pathogenesis of non-suicidal self-injury (NSSI) among adolescents. However, their role predicting outcome adolescent NSSI is unknown. This study aimed to explore relationship between inflammatory cytokines and effect on treatment through a prospective investigation. Thirty-two healthy adolescents 199 who had engaged were recruited. Blood samples obtained from all participants determine concentration at enrollment. Thereafter, group...
Acute myocardial infarction (AMI) with cardiovascular-kidney-metabolic (CKM) condition is linked to a high in-hospital mortality. Some previous studies reported that calcium may be related mortality among patients AMI. However, there no report about the association between serum and AMI CKM syndrome. Therefore, this study investigated admission levels in cohort of This retrospective enrolled 2537 admitted including 270 CKM. All data were extracted from electronic medical records May 2019...