A5058930926- Air Quality Monitoring and Forecasting
- Air Quality and Health Impacts
- Atmospheric chemistry and aerosols
- Cancer, Hypoxia, and Metabolism
- Microbial Metabolic Engineering and Bioproduction
- Epigenetics and DNA Methylation
- Pharmacological Effects of Natural Compounds
- Adipokines, Inflammation, and Metabolic Diseases
- Mitochondrial Function and Pathology
- Sirtuins and Resveratrol in Medicine
- Neurogenesis and neuroplasticity mechanisms
- Neuroscience and Neuropharmacology Research
- Diet and metabolism studies
- Adipose Tissue and Metabolism
University of Milan
2022-2024
The RHAPS (Redox-Activity And Health-Effects Of Atmospheric Primary Secondary Aerosol) project was launched in 2019 with the major objective of identifying specific properties fine atmospheric aerosol from combustion sources that are responsible for toxicological effects and can be used as new metrics health-related outdoor pollution studies. In this paper, we present overall methodology introduce phenomenology first data observed. A comprehensive physico-chemical characterization has been...
Abstract Neuronal maturation is the phase during which neurons acquire their final characteristics in terms of morphology, electrical activity, and metabolism. However, little known about metabolic pathways governing neuronal maturation. Here, we investigate contribution main pathways, namely glucose, glutamine, fatty acid oxidation, primary rat hippocampal neurons. Blunting glucose oxidation through genetic chemical inhibition mitochondrial pyruvate transporter reveals that this protein...
We previously reported that in the absence of Prostaglandin D2 synthase (L-PGDS) peripheral nerves are hypomyelinated development and with aging they present aberrant myelin sheaths. now demonstrate L-PGDS expressed Schwann cells is part a coordinated program aiming at preserving integrity.
Since white adipose tissue (WAT) lacks parasympathetic cholinergic innervation, the source of acetylcholine (ACh) acting on adipocyte receptors is unknown. This study was designed to identify ACh-producing cells in mouse and human visceral WAT determine whether a non-neuronal system becomes activated obese inflamed WAT. Mouse epididymal (eWAT) omental fat were studied normal subjects. The expression key molecules involved signaling evaluated by qRT-PCR western blotting whereas their...
The RHAPS project was launched in 2019 with the major objective to identify specific properties of fine atmospheric aerosol from combustion sources that are responsible for toxicological effects and can be used as new metrics health-related outdoor pollution studies. In this paper, we present overall methodology RHAPS, introduce phenomenology first data observed. A comprehensive physico-chemical characterization has been achieved by means high-time resolution measurements (e.g. number size...