- Pancreatic function and diabetes
- Epigenetics and DNA Methylation
- Diabetes and associated disorders
- Cardiovascular Effects of Exercise
- Hormonal Regulation and Hypertension
- Cerebrovascular and Carotid Artery Diseases
- Macrophage Migration Inhibitory Factor
- Nutritional Studies and Diet
- Digital Holography and Microscopy
- Growth Hormone and Insulin-like Growth Factors
- Galectins and Cancer Biology
- Magneto-Optical Properties and Applications
- Tendon Structure and Treatment
- Bone Metabolism and Diseases
- Orbital Angular Momentum in Optics
- Cancer Risks and Factors
- Quantum Mechanics and Non-Hermitian Physics
- Neuroendocrine regulation and behavior
- Health and Wellbeing Research
- Cardiovascular and exercise physiology
- Cancer Cells and Metastasis
- Cardiovascular Disease and Adiposity
- Immune responses and vaccinations
- Apelin-related biomedical research
- Image Processing Techniques and Applications
Guangzhou Medical University
2024
Sun Yat-sen Memorial Hospital
2023
Sun Yat-sen University
2023
Huazhong University of Science and Technology
2021
Tongji Hospital
2021
Kaohsiung Chang Gung Memorial Hospital
2020
Shandong First Medical University
2020
Guilin Medical University
2020
Shanghai Ninth People's Hospital
2019
Fu Wai Hospital
2016-2018
The toll-like receptor 4 (TLR4) agonist, Bacille Calmette-Guérin, has exhibited gratifying effects in treating bladder cancer. study aims to explore the expression pattern, prognostic value, and potential mechanism of TLR4 cancer.The transcriptome file from GSE13507 dataset Gene Expression Omnibus database promoter methylation cancer Cancer Genome Atlas were downloaded for analysis. value TLRs was assessed by univariate Cox regression. Immunohistochemistry applied verify drug response is...
To understand the function of human hydroxysteroid (17beta) dehydrogenase 2 (HSD17B2) in peripheral tissues vivo, we studied bone development transgenic male mice ubiquitously expressing HSD17B2. Bones HSD17B2TG and WT males (26 days 6 mo old) were analyzed by pQCT histomorphometry, data correlated with serum testosterone (T), IGF-I, osteocalcin concentrations. At age 26 days, body weight was significantly lower, lengths tibia femur shorter. Histomorphometric analyses showed lower trabecular...
The ovariectomized (OVX) rat, as an established animal model of human osteoporosis, was adopted in the present experiment to study protective effects sodium daidzein sulfonate (SDS) on trabecular bone. Six-month-old Sprague-Dawley rats were sham-operated or ovariectomized. Five days later, OVX randomly assigned one three experimental groups and treated for 90 with vehicle, 17beta-estradiol (E(2)) SDS. Compared rats, SDS administration (15 mg/kg) prevented OVX-induced decrease lumbar...
Abstract We theoretically investigate the enhancement of magneto-optical Goos-Hänchen (MOGH) shift in multilayer structure combining uniaxially anisotropic epsilon-near-zero (ENZ) metamaterials with (MO) materials. The enables excitation surface plasmon resonance (MOSPR) without need for a prism or grating coupler, thereby achieving significant MOGH shift. effect thickness ENZ layer and type magnetic metal this on is also discussed. Based above structure, we design high-sensitivity miniature...
<p dir="ltr"><b>ABSTRACT</b></p><p dir="ltr">Maturation of postnatal β cells is regulated in a cell-autonomous manner, and metabolically stressed regress to an immature state, ensuring defective β-cell function the onset type 2 diabetes. The molecular mechanisms connecting nutritional transition maturation remain largely unknown. Here, we report miR-203/ZBTB20/MAFA regulatory axis that mediates process. We show miR-203 level changes during inhibits at neonatal...
<p dir="ltr"><b>ABSTRACT</b></p><p dir="ltr">Maturation of postnatal β cells is regulated in a cell-autonomous manner, and metabolically stressed regress to an immature state, ensuring defective β-cell function the onset type 2 diabetes. The molecular mechanisms connecting nutritional transition maturation remain largely unknown. Here, we report miR-203/ZBTB20/MAFA regulatory axis that mediates process. We show miR-203 level changes during inhibits at neonatal...
Platelet-rich plasma (PRP) is widely utilized in the treatment of sports injuries. However, potential systemic effects after localized PRP injection are unclear at present. In this prospective randomized study, 24 Taiwanese male athletes with tendinopathy were into a group ( n = 13) or saline 11). The concentrations serum and urine biomarkers quantified by enzyme-linked immunosorbent assay assessment as well gas chromatographic mass spectrometric analysis, respectively. results showed no...
This study was to analyze the in vivo distribution of wall shear stress (WSS), velocity and inplane pressure difference normal carotid artery by using computational fluid dynamics (CFD) based on contrastenhanced MRA (CE-MRA) data determine whether there were differences these hemodynamic parameters between atherosclerosis-free atherosclerosis-prone areas.CE-MRA performed 16 arteries obtain three-dimensional surface data.CFD analysis then estimate those (distal common distal internal artery)...
Objective: Treadmill exercise test (TET) is one of the most common noninvasive diagnosis approaches for ischemic heart diseases, but potential reduction TET accuracy among Chinese women patients was ignored by studies, especially perimenopause women. Hence, we aim to perform a systematic review and meta-analysis evaluating diagnostic women, compared with coronary angiography (CAG). Design Method: PubMed (1990 2015), MEDLINE EMBASE CNKI 2015) WANFANG were performed identify studies assessing...
The mechanism for memory T helper (Th) cell differentiation in malignant pleural effusion (MPE) of non-small lung cancer (NSCLC) is poorly understood. MicroRNAs (miRNAs), as small non-coding RNA that regulate gene expression, play a crucial role the regulation Th differentiation. However, whether miRNAs can inhibit cells MPE NSCLC has not been reported. This study aimed to explore miR-16-5p specifically inhibits interferon-gamma (IFN-γ)-regulated NSCLC.
Objective To explore the living habits related to COPD relapse in elderly patient and present intervention measures aimed at health education community. Methods investigate 100 patients' last 3 years relevant factors included daily life relapse. Results In life, smoking air conditioner were main relapse, ventilation time, background age recurrence, they statistically significant ( P < 0. 05 or 01 ). Conclusions We should do more disseminate knowledge patients, encourage them reduce using of...
Objectives: To investigate the associations of metabolic syndromes (MS) and their components with estimated 24-hour urinary sodium excretion (24hUNaE) in Chinese adults. Methods: 40,693 participants aged 51.4 ± 9.7 years measurements blood biochemistry, pressure at baseline from a prospective urban rural epidemiology study China (PURE-China) were selected for final analyses. MS diagnosed based on NCEP-ATP III criteria. 24hUNaE was second fasting urine samples using Kawasaki formula....
Aspirin is essential in the primary and secondary prevention of hypertension. However, effect aspirin on blood pressure (bp) hypertensive patients has been controversial. Therefore, we quantitatively evaluated bp untreated antihypertensive patients. We searched PubMed, Embase Cochrane library electronic databases for articles published prior to June 2019. The overall changes systolic diastolic was estimated by using random-effects models according I2 statistic. A total 15 randomized...