Yang Chen

ORCID: 0009-0000-4273-9784
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About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Proteins in Food Systems
  • Asymmetric Hydrogenation and Catalysis
  • Graphene research and applications
  • Anaerobic Digestion and Biogas Production
  • Meat and Animal Product Quality
  • Cancer survivorship and care
  • Advanced Glycation End Products research
  • Cannabis and Cannabinoid Research
  • Inflammatory Bowel Disease
  • Surfactants and Colloidal Systems
  • Pediatric Pain Management Techniques
  • Helicobacter pylori-related gastroenterology studies
  • Pickering emulsions and particle stabilization
  • Membrane Separation Technologies
  • Advanced Sensor and Energy Harvesting Materials
  • Software System Performance and Reliability
  • Carbon dioxide utilization in catalysis
  • Diet, Metabolism, and Disease
  • Chemical Synthesis and Reactions
  • Family Support in Illness
  • Software-Defined Networks and 5G
  • Chemical Synthesis and Analysis
  • Carcinogens and Genotoxicity Assessment

Sichuan University
2025

West China Hospital of Sichuan University
2025

Jiangnan University
2015-2024

Shanghai University
2024

State Key Laboratory of Food Science and Technology
2015-2024

Taiyuan Maternity and Child Care Hospital
2024

Qingdao University of Science and Technology
2023

Qingdao University of Technology
2023

Peking Union Medical College Hospital
2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2023

This study was designed to explore the effects and discrepancy of different CLA-producing Bifidobacterium pseudocatenulatum on relieving colitis investigate potential mechanisms. B. MY40C CCFM680 were administered mice with DSS-induced colitis. The content tight junction proteins mucin2 significantly upregulated. TNF-α IL-6 downregulated, while IL-10 PPAR-γ TLR4/NF-κB pathway activation inhibited. Moreover, each treated strain increased Allobaculum decreased Sutterella, Bacteroides,...

10.1021/acs.jafc.0c06329 article EN Journal of Agricultural and Food Chemistry 2021-01-29

Recently, microbial changes in the human gut have been proposed as a possible cause of obesity. Therefore, modulation microbiota through probiotic supplements is great interest to support obesity therapeutics. The present study examines functional effect and metabolic targets bacterial strain, Bifidobacterium animalis subsp. lactis CECT 8145, selected from screening Caenorhabditis elegans. This strain significantly reduced total lipids (40.5% ± 2.4) triglycerides (27.6% 0.5), exerting...

10.1021/acs.jafc.5b05934 article EN Journal of Agricultural and Food Chemistry 2016-04-07

Irritable bowel syndrome with diarrhea and functional are both disorders that cause chronic diarrhea. Chronic is closely related to daily life the psychological condition of in patients, probiotics can play a significant role alleviating some research. Lactobaccilus plantarum CCFM1143 relieve mice caused by enterotoxigenic Escherichia coli (ETEC); however, its clinical effects remain unclear. This study aimed assess as therapy for patients. Fifty-five patients were randomly assigned into...

10.3389/fimmu.2021.746585 article EN cc-by Frontiers in Immunology 2021-10-15

The accumulation of heterocyclic amines (HAs) and advanced glycation end products (AGEs) during different processing stages was investigated in commercial raw materials to plant-based hamburger meats (PBHMs). Principal component analysis (PCA) performed explore the difference between samples each stage. total free HA level accumulated from 4.74-6.63 ng/g plant proteins 5.81-20.23 textured vegetable after extrusion. concentration MeAαC increased 29.23 ± 3.50 59.44 0.26 ng/g, resulting an...

10.1021/acs.jafc.2c06393 article EN Journal of Agricultural and Food Chemistry 2022-11-14

This study aimed to investigate the dose-response effect of Bifidobacterium breve CCFM683 on relieving psoriasis and its underlying patterns. Specifically, expression keratin 16, 17, involucrin were substantially decreased by administration 109 CFU 1010 per day. Moreover, interleukin (IL)-17 TNF-α levels CFU/day. Furthermore, gut microbiota in mice treated with or CFU/day was rebalanced improving diversity, regulating microbe interactions, increasing Lachnoclostridium, decreasing...

10.3390/nu15081952 article EN Nutrients 2023-04-18

Background Childhood adversities (CAs) and stressful life events (SLEs) are linked to depressive, anxiety, PTSD symptoms. However, their interrelationships not well studied. We aimed examine the potential role of symptoms as risk factors for both outcomes, test stress sensitization hypothesis, investigate pathways linking CAs, symptoms, depressive anxiety Methods conducted a cross-sectional study using data from adult participants at baseline (2006-2010) online follow-up (2016) in UK...

10.3389/fpsyt.2025.1488320 article EN cc-by Frontiers in Psychiatry 2025-03-21

Oil-in-water emulsions contain the inner oil phase, protein membrane at interface and aqueous phase. In this study, spatial partition of resveratrol was investigated in sunflower oil, fish medium-chain triglyceride (MCT) peppermint stabilized by native whey isolate (WPI), heat-denatured WPI sodium caseinate. Resveratrol added phase its analyzed term solubility bulk protein, concentration interfacial protein. The final concentrations were basically greater than those MCT emulsions, while...

10.3390/antiox12030589 article EN cc-by Antioxidants 2023-02-27

Abstract Oleoyl ethanolamide is a lipid mediator that exhibits biological activity in animal and cell models. In this study, an effective process described to synthesize oleoyl by chemical amidation with native oil used as acyl donor the presence of sodium methoxide. Reaction conditions were optimized. When reaction was conducted mixed solvent, reacting 2 mmol high oleic sunflower 20 ethanolamine 1.5 % methoxide agitation, >90 fatty acid formed after 3 h time. The product purified...

10.1007/s11746-015-2749-6 article EN Journal of the American Oil Chemists Society 2015-11-12

10.1016/j.acap.2016.01.003 article EN Academic Pediatrics 2016-01-20

Cellular retinaldehyde-binding protein (CRALBP) carries 11-cis-retinal and/or 11-cis-retinol as endogenous ligands in the retinal pigment epithelium (RPE) and Müller cells of retina has been linked with autosomal recessive retinitis pigmentosa. Ligand interactions determine physiological role CRALBP RPE where is thought to function a substrate carrier for dehydrogenase synthesis visual regeneration. However, also present optic nerve brain its natural ligand are not yet known. We have...

10.1074/jbc.273.33.20712 article EN cc-by Journal of Biological Chemistry 1998-08-01
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