A5100932413- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Lower Extremity Biomechanics and Pathologies
- Anesthesia and Sedative Agents
- Gut microbiota and health
- Anesthesia and Neurotoxicity Research
- Diet and metabolism studies
- Cardiac Arrest and Resuscitation
- Adrenal Hormones and Disorders
- Ear Surgery and Otitis Media
- Acupuncture Treatment Research Studies
- Nutrition, Health and Food Behavior
- Infant Health and Development
- Medical Imaging Techniques and Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Infant Development and Preterm Care
- Pelvic and Acetabular Injuries
- Sports injuries and prevention
- Health and Wellbeing Research
- Contact Dermatitis and Allergies
- Neonatal Health and Biochemistry
- Endoplasmic Reticulum Stress and Disease
- Occupational exposure and asthma
Air Force Medical University
2024-2025
Tongren Hospital
2024-2025
Shanghai Jiao Tong University
2024-2025
Beijing Friendship Hospital
2025
Capital Medical University
2025
Xian Yang Central Hospital
2021-2024
Chinese PLA General Hospital
2024
Shaanxi University of Chinese Medicine
2024
Xijing Hospital
2024
Nantong University
2024
Diarrhea and constipation are common health concerns in children. Numerous studies have identified strong association between gut microbiota digestive-related diseases. But little is known about the that simultaneously affects both diarrhea or their potential regulatory mechanisms. Stool samples from 618 children (66 diarrhea, 138 constipation, 414 healthy controls) aged 0-3 years were collected to investigate changes using 16S rRNA sequencing. Compared with healthy, exhibited a significant...
This prospective diagnostic study aimed to assess the utility of machine learning-based quadriceps fat pad (QFP) radiomics in distinguishing patellofemoral osteoarthritis (PFOA) from non-PFOA using Q-Dixon MRI patients presenting with anterior knee pain. accuracy retrospectively analyzed data 215 (mean age: 54.2 ± 11.3 years; 113 women). Three predictive models were evaluated: a proton density-weighted image model, fraction and merged model. Feature selection was conducted analysis variance,...
High-dose (HD) tigecycline is often required for severe multidrug-resistant gram-negative infections in liver failure patients, despite package recommendations to halve the dose those with impairment. This study evaluated efficacy and safety of different doses this population. A retrospective cohort 192 patients Child-Pugh grade C was divided into label-dose (LD), standard-dose (SD), HD groups. Primary secondary outcomes included microbial eradication, mortality, adverse effects. The SD...
ATG9A is a transmembrane protein essential for macroautophagy/autophagy that drives autophagosome formation by delivering proteins and lipids to the phagophore through vesicle trafficking. Here, we demonstrate atypical Rho GTPase RHOD required trafficking stimulates formation. Upon starvation, interacted with accompanied from Golgi toward phagophores. In addition, starvation-induced high levels of resulted in fragmentation further promote export trans-Golgi network peripheral region. Loss...
Membrane channel proteins (MCPs) play key roles in matter transport through cell membranes and act as major targets for vaccines drugs. For emerging ionic liquid (IL) drugs, a rational understanding of how ILs affect the structure function MCP is crucial to their design. In this work, GPU-accelerated microsecond-long molecular dynamics simulations were employed investigate modulating mechanism on MCP. Interestingly, prefer insert into lipid bilayer aquaporin-2 (AQP2) but adsorb entrance...
Abstract Background Contrast-induced encephalopathy (CIE) is a rare complication during or after angiography, usually transient and reversible. CIE diagnosis challenging due to the absence of no formal diagnostic criteria. can mimic stroke symptoms, including visual disturbances, seizures, confusion, coma, focal neurological deficits. This case reports deficit reversal in patient embolization an intracranial aneurysm, second angiographic procedure six days. Case presentation A 77-year-old...
Severe combined immunodeficient (SCID) mice serve as a critical model for human xenotransplantation studies, yet they often suffer from low engraftment rates and susceptibility to graft-versus-host disease (GVHD). Moreover, certain SCID strains demonstrate ‘immune leakage’, underscoring the need novel development. Here, we introduce an mouse with targeted disruption of dclre1c gene, encoding Artemis, which is essential V(D)J recombination DNA repair during T cell receptor (TCR) B (BCR)...
Anterior knee pain (AKP) is a common symptom of patellofemoral osteoarthritis (PFOA). There limited prospective evidence supporting the relationships between maltracking parameters, AKP, and PFOA. Thus, this cross-sectional study aimed to determine association quadriceps fat pad (QFP) edema in patients with chronic AKP evaluate feasibility diagnostic performance PFOA assessment using fraction (FF) T2* based on Q-Dixon.
Objective: To investigate the curative effect of remifentanil on analgesia in newborns.Patients and methods: One hundred twenty full-term puerperae from January 2013 to December were selected randomly divided into three groups: patient-controlled intravenous labor group (Group A, n = 40), epidural (PCEA) B, spontaneous C, 40). General conditions, visual analogue scale (VAS) score, stage, bleeding, delivery mode, neonatal asphyxia rate, oxyhemoglobin saturation puerpera, umbilical arterial...
<title>Abstract</title> Gastric cancer remains a leading cause of cancer-related deaths with considerable heterogeneity among patients. Accurate classifications play pivotal role in prognosis prediction and personalized therapeutic strategies. Considering the practicality typing its closer clinical relevance, this study, we leveraged multi-omics data, specifically transcriptomics RNA-sequencing (mRNA) DNA methylation data from TCGA-STAD cohort, for clustering analysis. The integration...
Background: The pathology and prognosis of prostate cancer (PCa) in the peripheral zone (PZ) are worse than transition (TZ), but intra-tumor heterogeneity (ITH) differences between them is unknown.Methods: Preoperative MRI scans were retrospectively acquired PCa patients who underwent radical prostatectomy (RP) from January 2018 to February 2024. PCas classified TZ PZ using RP results as gold standard. Intergrating multimodal imaging data, lesions clustered into different habitat subregions....
This study was to explore the application value of B-ultrasound in guiding puncture biopsy chronic kidney disease (CKD) and clinical nursing effects under guidance B-ultrasound.Pathological examination performed on 94 patients with CKD ultrasound from August 2020 December 2020.; were observed for symptoms such as low back pain, backache, hematuria, subcapsular hematoma. Color Doppler ultrasonography punctured day 1, 2, 3 observe whether there subrental The pathological results analyzed...
Purpose: To study the effects of various dexmedetomidine (DEX) doses on post-surgical emergence agitation (EA) and oxidative stress in children.Methods: At times, mean arterial pressure (MAP) heart rate (HR) were measured: prior to anesthesia (T0), during intubation (T1), at onset operation (T2), end surgery (T3). The incidence EA was estimated, extent determined based pediatric delirium (PAED). Post-surgical pain using facial scale (FPS). Serum levels cortisol (Cor), epinephrine (E),...
Abstract Diarrhea and constipation are common health concerns during childhood, with an estimated prevalence of 3% to 9% worldwide. Although numerous studies have identified strong association between gut microbiota digestive-related diseases in children, little is known about the that simultaneously affects both diarrhea or their potential regulatory mechanisms. Here, we conducted a cohort study on 618 individuals (66 138 constipation) via 16S rRNA sequencing stool. Compared healthy...
Abstract Objectives Primary aldosteronism (PA) is a common but underdiagnosed secondary cause of hypertension. Emergency departments (EDs) often assess patients with severe hypertension or its sequelae, some whom have underlying PA. We aimed to determine the proportion presenting ED who meet Endocrine Society criteria for PA testing and were screened. Methods performed structured retrospective chart review adults presented three EDs in an Australian tertiary health network between August...
With the prevalence of allergic contact dermatitis (ACD) from usage skin-contact products, like wearable, skin care, and hair care screening their sensitizing potential is necessary, for sake alleviating consequent public health impact. In present study, a total 77 products classified by four categories, watch bands (WBs), (SCPs), (HCPs), rubber gloves (RGs), were investigated, using an optimized in vitro assay human cell line activation test (h-CLAT). Extracting neutral artificial sweat...