A5033227717- Pregnancy and preeclampsia studies
- Nitric Oxide and Endothelin Effects
- Birth, Development, and Health
- Cardiovascular Issues in Pregnancy
- Antioxidant Activity and Oxidative Stress
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Reproductive Physiology in Livestock
- Fatty Acid Research and Health
- Electrolyte and hormonal disorders
- Inflammatory mediators and NSAID effects
- Neuroscience of respiration and sleep
- Adipose Tissue and Metabolism
- Cardiovascular Health and Disease Prevention
- Renin-Angiotensin System Studies
- Hospital Admissions and Outcomes
- Gestational Diabetes Research and Management
- Nursing Education, Practice, and Leadership
- Patient Safety and Medication Errors
- Thermoregulation and physiological responses
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Diversity and Career in Medicine
- Crystallization and Solubility Studies
- Abdominal vascular conditions and treatments
University of South Florida
2024
University of Michigan
2012-2014
Indiana University – Purdue University Indianapolis
2014
Committee on Publication Ethics
2014
E Ink (South Korea)
2014
University of Pittsburgh
1994-2004
Magee-Womens Research Institute
1994-2001
St. Catherine University
2001
Magee-Womens Hospital
2001
University of Washington
1998
Preeclampsia is a disorder of pregnancy diagnosed by gestational hypertension and proteinuria. Epidemiological evidence suggests that women who experience preeclampsia are at greater risk heart disease later in life compared with had normal pregnancies. Our objective was to determine whether endothelial function impaired postpartum history their first pregnancy. We measured forearm blood flow (FBF) venous occlusion plethysmography 50 healthy women: 16 prior preeclampsia, 14 normotensive...
Abstract The endothelium serves many functional roles, including the modulation of vascular smooth muscle tone through release vasoactive agents such as nitric oxide (NO) and eicosanoids. We proposed that NO produced by endothelial cells would increase production eicosanoids enhanced expression and/or activation prostaglandin H synthase. eicosanoid synthesis were stimulated in a bovine coronary microvessel cell line with calcium ionophore A23187 (1 μmol/L). Our data demonstrated following:...
Although the function of metallothionein (MT), a 6- to 7-kDa cysteine-rich metal binding protein, remains unclear, it has been suggested from in vitro studies that MT is an important component intracellular redox signaling, including being target for nitric oxide (NO). To directly study interaction between and NO live cells, we generated fusion protein consisting sandwiched two mutant green fluorescent proteins (GFPs). In with this chimera (FRET-MT) demonstrate resonance energy transfer...
The purpose of this study was to test the use virtual simulation improve teamwork among nursing staff. Using a quasi-experimental design, staff (n = 43) from one patient care unit participated in 1-hr session, which focused on common problems. overall mean scores improved pre- (M 3.25, SD 0.58) post-intervention 3.49, 0.67, p < .012). intervention also had large (0.60 ≤ d 0.97) and significant effects measures three subscales (i.e., trust, team orientation, backup).
We tested the hypothesis that endothelin acting through endothelial ET B receptor subtype and nitric oxide (NO) pathway accounts for reduced myogenic reactivity of renal resistance vasculature during pregnancy. Small arteries (100–200 μm) were isolated from virgin midterm pregnant rats when gestational hyperfiltration vasodilation are maximal in this species. Myogenic (the adjustment arterial diameter response to a change transmural pressure) was assessed with pressurized myograph system. A...
Live virus vaccines can cause serious adverse reactions when administered to immunocompromised patients. Because children infected with human immunodeficiency (HIV) may be immunosuppressed, immunization of these live is a potential problem. A retrospective survey was conducted by the New York City Department Health, consultation from Centers for Disease Control, evaluate frequency events following receipt among HIV infection receiving pediatric care in and Jersey. Outpatient records 319...
Changes in the uterine and umbilical circulations during induced hypercapnia were studied nine unanesthetized near-term pregnant sheep. Blood flows measured with electromagnetic flow transducers arterial pressures vascular catheters implanted under anesthesia 2–16 days prior to experiments. Hypercapnia was fetus alone by giving acetazolamide iv fetus, 100–200 mg/kg. Mean fetal Pco2 increased from49.5 63.4 mmHg but no significant changes blood flowoccurred. Stepwise increases both maternal...
Recordings of 30-minute dyadic conversations between strangers were coded for the frequency occurrence 11 story receipt and eight sequencing variables, duration all storytellings, sequences. Analysis data indicated that (1) females spent significantly more time than males as recipients storytelling; (2) differed on a linear combination five variables (displays interest tokens, appreciates, adds or predicts details, withholds sequential talk, talk at story's end); (3) there no significant...