A5101756802- Cancer-related molecular mechanisms research
- Glioma Diagnosis and Treatment
- Circular RNAs in diseases
- MicroRNA in disease regulation
- CRISPR and Genetic Engineering
- RNA modifications and cancer
- Animal Genetics and Reproduction
- Metabolomics and Mass Spectrometry Studies
- Peroxisome Proliferator-Activated Receptors
- Traditional Chinese Medicine Analysis
- Advanced Memory and Neural Computing
- Renal and related cancers
- Cancer, Hypoxia, and Metabolism
- Nanoplatforms for cancer theranostics
- Pluripotent Stem Cells Research
- Gout, Hyperuricemia, Uric Acid
- Liver Disease Diagnosis and Treatment
- 2D Materials and Applications
- Magnesium in Health and Disease
- Ubiquitin and proteasome pathways
- Sesame and Sesamin Research
- Ion Transport and Channel Regulation
- Concrete Corrosion and Durability
- Viral Infections and Immunology Research
- Perovskite Materials and Applications
Anhui Medical University
2021-2025
First Affiliated Hospital of Anhui Medical University
2025
Massachusetts General Hospital
2025
Harvard University
2025
Research Network (United States)
2025
Fudan University
2009-2024
Nanjing Children's Hospital
2024
Nanjing Medical University
2024
Shanghai CASB Biotechnology (China)
2024
China University of Petroleum, Beijing
2022-2024
Pain-perceptual nociceptors (PPN) are essential sensory neurons that recognize harmful stimuli and can empower the human body to react appropriately perceive precisely unusual or dangerous conditions in real world. Furthermore, sensitization-regulated (SRN) greatly assist pain-sensitive reduce pain sensation by normalizing hyperexcitable central neural activity. Therefore, implementation of PPNs SRNs hardware using emerging nanoscale devices improve efficiency bionic medical machines giving...
Abstract Digital PCR (dPCR) holds immense potential for precisely detecting nucleic acid markers essential personalized medicine. However, its broader application is hindered by high consumable costs, complex procedures, and restricted multiplexing capabilities. To address these challenges, an all‐in‐one dPCR system introduced that eliminates the need microfabricated chips, offering fully automated operations enhanced Using this innovative oscillation‐induced droplet generation technique,...
The unclear effects of microwaves, as a greener alternative to hot air, on sensory perception, aroma, and hazardous components sesame oil were investigated. Microwaves (900 W, 6–10 min) created more seed porosity cell destruction facilitated γ-tocopherol release in (349.30–408.50 mg/kg) than 200 °C, 20 min air (304.90 mg/kg). (6–10 generated aromatic heterocyclics (42.40–125.12 aldehydes (5.15–2.08 (25.59 mg/kg 1.34 (6 produced with stronger roasted flavour, weaker bitter burnt flavour air....
Ischemic stroke is a serious health hazard that lacks effective treatment strategies. This study aims to investigate baicalin’s effect on tight junctions and immune cell infiltration after ischemic injury. Rat brain microvascular endothelial cells (BMECs) were treated with OGD/R establish an in vitro model. Caspase-3, Bax, Bcl-2, zonula occludens-1 (ZO-1), occludin, claudin-5, tumor necrosis factor (TNF)-[Formula: see text], interleukin (IL)-6, inducible nitric oxide synthase (iNOS),...
Actin depolymerizing factor (ADF) is a key modulator for dynamic organization of actin cytoskeleton. Interestingly, it was found that the ADF1 gene silencing delays flowering, but its mechanism remains unclear. In this study, used as bait to screen interacting proteins by yeast two-hybrid (Y2H) system. One them, REM16 transcription identified. As one AP2/B3-like transcriptional family members, contains two B3 domains and transcript levels kept increasing during floral transition stage....
Promoter status of O6-methylguanine-DNA methyltransferase (MGMT) has been widely established as a clinically relevant factor in glioblastoma (GBM) patients. However, addition to varied therapy schedule, the prognosis GBM patients is also affected by variations age, race, primary or recurrent tumor. This study comprehensively investigated association between MGMT promoter and overall different subtype including new diagnosed patients, elderly patients.A comprehensive search was performed...
Abstract Recent years have witnessed rapid developments in organic–inorganic hybrid perovskites, among which 2D Ruddlesden–Popper (RP) perovskites stand out due to their outstanding ambient stability. In photodetector applications, RP are mostly limited lateral device configuration because of preferred in‐plane charge transportation within quantum well structures. this work, the low‐temperature solution construction perovskite‐based photodiodes vertical architecture is demonstrated. The...
Background: Inflammation plays an important role in tumorigenesis. Previous studies have reported the prognostic value of several peripheral inflammatory markers glioma patients, including neutrophil-to-lymphocyte ratio (NLR). However, it still remains unclear whether can independently predict prognosis glioblastoma (GBM) patients. The present study aims to explore systemic markers, neutrophils, lymphocytes, platelets, NLR, and platelet-to-lymphocyte (PLR), patients with GBM. Methods: A...
Biological bipolar metaplasticities were successfully mimicked in two-dimensional (2D) MoS 2 transistors via the implementation of two different surface decorations, poly (vinyl alcohol) (PVA) and chitosan bio-polymers. Interestingly, depressing metaplasticity was when PVA bio-polymer used as decoration layer, whereas long-term potentiation realized taken layer. Furthermore, electronic band structures 2D devices with decorations further investigated using first-principles calculations for...
Background and Objectives: Mutations in the Leucine-rich repeat kinase 2 (LRRK2) gene are one of most common genetic causes Parkinson's disease (PD) linked to immune dysregulation both central nervous system periphery. However, peripheral profiles soluble factors associated with LRRK2 mutations PD have not been comprehensively characterized. Using serum CSF samples from Cohort Consortium (LCC), this study aimed probe a broad range biomarkers PD. Methods: We investigated levels regulators...
The trophoblast (TR) is the first to differentiate during mammalian embryogenesis and play a pivotal role in development of placenta. We used dual inhibitor system (PD0325901 CHIR99021) with mixed feeders successfully obtain bovine stem-like (bTS) cells, which were similar phenotype mouse stem cells (TSCs). bTS that generated using this continually proliferated, displayed normal diploid karyotype, had no signs altered morphology or differentiation even after 150 passages. These exhibited...
As Th22 subsets are identified, their involvement in the pathogenesis of numerous autoimmune diseases has become apparent. In this study, we investigated differentiation cells thyroid including Hashimoto's thyroiditis (HT) and Graves' disease (GD). Besides, also explored an iodine-induced (AIT) model (i.e., NOD.H-2(h4) mice). HT patients, showed level circulating correlated with serum IL-22, was significantly higher than GD patients healthy control subjects. Levels IL-6, a major cell...