- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Bacterial Infections and Vaccines
- Parasites and Host Interactions
- Antibiotic Resistance in Bacteria
- Indigenous Health and Education
- Fungal Infections and Studies
- Parasitic Infections and Diagnostics
- Child Nutrition and Water Access
- Antimicrobial Resistance in Staphylococcus
- Acne and Rosacea Treatments and Effects
- Cassava research and cyanide
- Plant Pathogenic Bacteria Studies
- Infections and bacterial resistance
- Healthcare Regulation
- Blood groups and transfusion
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Bacterial Identification and Susceptibility Testing
- Reproductive Health and Contraception
- Streptococcal Infections and Treatments
- Neurological Complications and Syndromes
- melanin and skin pigmentation
- Enterobacteriaceae and Cronobacter Research
- Geography and Environmental Studies
Fundação de Medicina Tropical
2011-2024
Dermatology Foundation
2012-2024
Beneficência Portuguesa de São Paulo
2021
Universidade do Estado do Amazonas
2011-2020
Universidade Estadual da Paraíba
2014
Fundação de Amparo à Pesquisa do Estado do Amazonas
2013
Universidade Nilton Lins
2009
Gonorrhoea and antimicrobial resistance (AMR) in Neisseria gonorrhoeae are major public health concerns globally. Enhanced AMR surveillance for gonococci is essential worldwide; however, recent quality-assured gonococcal Latin America, including Brazil, has been limited. Our aims were to (i) establish the first nationwide surveillance, quality assured according WHO standards, (ii) describe susceptibility of clinical isolates collected from 2015 2016 all five main regions (seven sentinel...
Neisseria gonorrhoeae antimicrobial resistance (AMR) surveillance is imperative internationally, but only eight (22.9%) countries in the WHO Region of Americas reported complete AMR data to Global Gonococcal Antimicrobial Surveillance Program (WHO GASP) 2016. Genomic studies are ideal for enhanced understanding gonococcal populations, including spread strains. To elucidate circulating lineages/sublineages, their determinants, and baseline genomic diversity among strains Brazil, we conducted...
Antibiotic therapy in hematologic patients, often weak and susceptible to a wide range of infections, particularly nosocomial infections derived from long hospitalization periods, is challenging issue. This paper presents ESBL-producing strains isolated such patients treated at the Amazon Hematology Hemotherapy Foundation (HEMOAM) Brazilian Region identify ESBL genes carried by them as well susceptibility 11 antimicrobial agents using E-test method. A total 146 clinical samples were obtained...
Background Little is known about the aetiology of urethral discharge syndrome (UDS) and genital ulcer disease (GUD) in Brazil due to limited access laboratory tests treatment based mainly on syndromic approach. Objectives To update Brazilian guidelines according current scenario, first nationwide aetiological study for UDS GUD was performed. Methods Male participants with (UD) and/or (GU) reports were enrolled. Sample collection performed by 12 sentinel sites located five regions. Between...
Background: Currently, the Enterobacteriaceae species are responsible for a variety of serious infections and already considered global public health problem, especially in underdeveloped countries, where surveillance monitoring programs still scarce limited. Analyses were performed on complete genome an extensively antibiotic-resistant strain Enterobater hormaechei, which was isolated from patient with non-Hodgkin’s lymphoma, who had been admitted to hospital city Manaus, Brazil. Methods:...
BACKGROUND This case report describes a of 25-year-old man who underwent surgical procedure and was subsequently diagnosed with acute myeloid leukemia. Following his immediate admission to specialized hospital unit for hematology hemotherapy receive chemotherapy, he found have concurrent infection multidrug-resistant Elizabethkingia meningoseptica as well Enterococcus faecium. Both isolates are commonly associated healthcare-associated infections. CASE REPORT The patient described in this an...
Hospital or community acquired methicillin-resistant Staphylococcus aureus(MRSA) have been described as an important public health problem, becausetheir resistance to beta-lactam and others antibiotics like macrolides, lincosamides,clindamycin, aminoglycosides sulfonamides. In this study we identified MRSAprevalence at the Foundation of Tropical Dermatology Venereology Alfredo daMatta in Manaus, Brazil. The data were obtained from culture susceptibilitytests register book, clinical...
We report two ciprofloxacin and ofloxacin-resistant Neisseria gonorrhoeae strains that were isolated from the urethral discharge of male patients at sexually transmitted diseases outpatient clinic Alfredo da Matta Foundation (Manaus, state Amazonas, Brazil). The gonococci displayed minimal inhibitory concentrations (> 32.00 µg/mL) three mutations in quinolone resistance-determining region (S91F D95G GyrA S87R ParC). Both isolates genotyped using N. multi-antigen sequence typing analysis...
Abstract Background Cryptococcosis is a disease of wide geographic distribution. It most critical when it affects immunocompromised patients, with AIDS, tuberculosis or other diseases that require prolonged hospitalization. Methods This study described case report, molecular epidemiology, the phylogenetic relationship, along antifungal susceptibility test new ST 623 C. neoformans isolated in patient non-Hodgkin’s Lymphoma, from Manaus, Brazil. Results The was susceptible to all drugs tested....
Methicillin-resistant Staphylococcus remains a severe public health problem worldwide. This research was intended to identify the presence of methicillin-resistant coagulase-negative staphylococci clones and their staphylococcal cassette chromosome mec (SCCmec)-type isolate from patients with haematologic diseases presenting bacterial infections who were treated at Blood Bank state Amazonas in Brazil. Phenotypic genotypic tests, such as SCCmec types multilocus sequence typing (MLST),...
We report new sequence types of 14 penicillinase-producing Neisseria gonorrhoeae, isolated from sexually transmitted disease clinic attendees in Manaus, Brazil. They were characterized by WI/WII/WIII groups, susceptibility testing and Multi-Antigen Sequencing Typing/Mutilocus Sequence Typing protocols. Twelve classified as WII/III 2 WI presented resistance to penicillin tetracycline. New alleles for por AroE genes novel identified, revealing molecular characteristics not described...
Abstract Background Healthcare workers are susceptible to colonization by multiresistant bacteria, which can increase the risk of outbreaks. Methods Samples were collected from nasopharynx, hands, and lab coats healthcare workers. The phenotypic identification was carried out using a VITEK®2 rapid test system. PCR tests for mec A gene sequencing amplicons performed. Staphylococcus epidermidis aureus phylogenies reconstructed Bayesian inference. Results total 225 participated in this study....
Abstract Objectives Regular quality-assured WGS with antimicrobial resistance (AMR) and epidemiological data of patients is imperative to elucidate the shifting gonorrhoea epidemiology, nationally internationally. We describe dynamics gonococcal population in 11 cities Brazil between 2017 2020 emerging disappearing lineages associated AMR, compare Brazilian AMR from 2015 2016, explain recent changes epidemiology. Methods was performed using Illumina NextSeq 550 genomes 623 isolates were used...
Salmonella Typhi is a zoonotic pathogen responsible for life-threatening bloodstream infection that common in places with limited sanitation and hygiene. This study aimed to characterize the resistance genes sequence type (ST) of Paratyphi isolated from patient acute myeloid leukemia (AML) undergoing treatment at Fundação HEMOAM, north Brazil. Phenotypic identification antimicrobial susceptibility testing were performed using VITEK-2 system. The genomic DNA was sequenced Illumina® equipment....
Introdução: A doença inflamatória intestinal (DII) é uma enteropatia crônica que causa distúrbios gastrointestinais em cães e gatos. Pode resultar perda de proteína geralmente quando um tipo enterite linfoplasmocitária. Nesse caso, frequentemente está associada à linfangiectasia. Os sinais clínicos incluem diarreia, vômitos peso progressiva. Esta afeta principalmente animais meia-idade. Existe apenas relato cão jovem nenhum foi observado na raça Dachshund. O objetivo deste artigo relatar a...
In last few decades, gonococci have developed resistance to all the antibiotics used as first line of treatment for gonococcal infections, leaving Extended- Spectrum Cephalosporins (ESCs) remaining option gonorrhea [1,2].
Chryseobacterium indologenes is an emerging nosocomial pathogen that produces IND-type chromosomal metallo-beta-lactamase. The phenotype and molecular aspects of two multidrug resistant C. strains the analysis tertiary structure IND enzyme were studied. Identification species susceptibility tests performed using Vitek-2 compact. Chromosomal plasmid DNA extracted PureLink™ Genomic Mini Kit PureLink Quick Plasmid Miniprep Kit, sequencing was ABI 3130 genetic analyzer. Two isolated are...
Objectives: To describe the prevalence of intestinal parasitosis in patients who sought a Basic Health Unit and get to know conditions socio-environmental characteristics population peri-urban area Manaus - AM, Brazil. Methods: A study conducted by spontaneous demand Unit, Northern Zone Manaus, Amazonas, between April July 2007, conducting parasitological examination 400 stool samples Hoffmann-Pons-Janer’s method, interviews. Results: From total, 271/400 (67,8%) contained parasites; 181/268...