A5062226440- Respiratory Support and Mechanisms
- Electrical and Bioimpedance Tomography
- Hemodynamic Monitoring and Therapy
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Respiratory Health Research
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Anesthesia and Pain Management
- Non-Invasive Vital Sign Monitoring
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Anesthesia and Sedative Agents
- Enhanced Recovery After Surgery
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Organ Transplantation Techniques and Outcomes
- Innovations in Medical Education
- Abdominal Surgery and Complications
- Intravenous Infusion Technology and Safety
- Radiology practices and education
- Transplantation: Methods and Outcomes
Medizinische Hochschule Hannover
2012-2025
University of Lübeck
2006-2014
University Medical Center
2007-2008
University Hospital Schleswig-Holstein
2006-2007
RWTH Aachen University
2006
Royal Brompton Hospital
2006
University of Freiburg
2006
IRCCS Policlinico San Donato
2006
Integrated Cardio Metabolic Centre
1989
Electrical impedance tomography (EIT) is a non-invasive bedside tool which allows an individualized ventilator strategy by monitoring tidal ventilation and lung aeration. EIT can be performed at different cranio-caudal thoracic levels, but data are missing about the optimal belt position. The main goal of this prospective observational study was to evaluate impact electrode layers on variation in relation global volume changes order propose proper position for measurements.EIT measurements...
Dynamic thoracic EIT is capable of detecting changes the ventilation distribution in lung. Nevertheless, it has yet to become an established clinical tool. Therefore, necessary consider application scenarios wherein fast and distinct tissue conductivities are be found also have a clear diagnostic significance. One such scenario artificial patients suffering from acute respiratory distress syndrome (ARDS). New protective strategies involving recruitment manoeuvres associated with noticeable...
Background: Anesthesia per se and pneumoperitoneum during laparoscopic surgery lead to atelectasis impairment of oxygenation. We hypothesized that a ventilation with positive end-expiratory pressure (PEEP) general anesthesia leads more homogeneous distribution as determined by electrical impedance tomography (EIT). Furthermore, we supposed PEEP in lung-healthy patients would improve the parameters oxygenation respiratory compliance. Methods: Thirty-two scheduled undergo cholecystectomy were...
BACKGROUND: Consensus regarding on-support evaluation and weaning concepts from Impella 5.5 support is scarce. The derived left ventricular end-diastolic pressure (dLVEDP), estimated by device algorithms, a rarely reported tool for monitoring the process. Its validation clinical accuracy have not been studied in patients. We assess dLVEDP’s predicting pulmonary capillary wedge (PCWP) propose corrective equation. METHODS: included 29 consecutive patients treated with 5.5: 12 generation cohort...
Background Post‐operative positive end‐expiratory pressure ( PEEP ) setting to minimize the risk of ventilator‐associated lung injury is still controversial. Assessment regional ventilation distribution by electrical impedance tomography EIT might be superior as compared with global parameters. The aim this prospective observational study was compare dynamic compliance C RS different indices during a short clinical applicable descending trial. Methods Twenty mechanically ventilated patients...
Transapical transcatheter aortic valve implantation (TA-TAVI) is increasingly used to treat stenosis in high-risk patients. Mixed venous oxygen saturation (SvO2) still the 'gold standard' for determination of systemic delivery consumption ratio cardiac surgery Recent data suggest that regional cerebral (rScO2) determined by near-infrared spectroscopy closely related SvO2. The present study compares rScO2 and SvO2 patients undergoing TA-TAVI. n = 20 scheduled TA-TAVI were enrolled this...
To determine whether the results of functional residual capacity measurements after endotracheal suctioning could guide decision to perform an alveolar recruitment maneuver and thus improve lung function.Prospective, randomized, controlled interventional study.Intensive care unit a university hospital.Fifty-nine mechanically ventilated patients within 2 hrs elective cardiac surgery without preexisting diseases.Patients received standard procedure with disconnection ventilator (20 secs, 14 F...
Non-intubated uniportal video-assisted thoracoscopic surgery (niVATS) is a novel approach to major and minor lung resection. It benefits from holistic anesthesiological concept with adequate pain relief sedation in minimal-invasive setup allowing thoracic procedures under spontaneous breathing. At present no gold standard for niVATS exists. The primary aim of our retrospective observational study was evaluate feasibility safety minimally invasive both pulmonary resections at institution.All...
Objectives: To compare the effect of student examiners (SE) to that faculty (FE) on examinee performance in an OSCE as well post-assessment evaluation area emergency medicine management.Methods: An test-format (seven stations: Advanced Cardiac Life Support (ACLS), Basic (BLS), Trauma-Management (TM), Pediatric-Emergencies (PE), Acute-Coronary-Syndrome (ACS), Airway-Management (AM), and Obstetrical-Emergencies (OE)) was administered 207 medical students their third year training after they...
Intra-articular injection of local anaesthetics, opioids and corticosteroids is frequently used to obtain perioperative analgesia following joint surgery. Although anaesthetics were shown induce chondrotoxicity, the safety profile regarding chondrotoxicity other injected drugs less clear.Our objective was investigate cytotoxicity for intra-articular analgesia.An experimental in-vitro study.Hannover Medical School, science laboratory, 2013.Human cartilage cell line T/C 28-a2.Incubation cells...
Abstract There is no agreement on gold standard method for positive end-expiratory pressure (PEEP) titration. Electrical impedance tomography (EIT) may aid in finding the optimal PEEP level. In this pilot trial, we investigated potential differences suggested ( BestPEEP ) as derived by respiratory compliance and EIT-derived parameters. We examined if compliance-derived differs with regard to regional ventilation distribution relation atelectasis hyperinflation. Measurements were performed...
Fast-track cardiac anaesthesia programs aiming at early tracheal extubation have not only been linked to a decrease in intensive care unit and hospital length of stay but also morbidity mortality as well containment rising medical costs. General recommendations for the inclusion criteria concerning fast-track are available. The present study determined factors influencing time patients undergoing newly implemented protocol. Seventy-nine were retrospectively studied. Successful fast track was...
Open endotracheal suctioning procedure (OSP) and recruitment manoeuvre (RM) are known to induce severe alterations of end-expiratory lung volume (EELV). We hypothesised that EIT volumes lack clinical validity. studied the suitability estimate EELV compared oxygen wash-in/wash-out technique.Fifty-four postoperative cardiac surgery patients were enrolled received standardized ventilation OSP. Patients randomized into two groups receiving either RM after (group RM) or no NRM). Measurements...
Pulmonary complications have a major impact on the morbidity and mortality of critically ill patients with multiple trauma. Intraoperative protective ventilation low tidal volume may prevent lung injury infection, whereas role positive end-expiratory pressure (PEEP) levels is unclear. The aim this study was to evaluate influence different intraoperative PEEP incidence pulmonary after emergency trauma surgery.We retrospectively analysed data who underwent surgery within 24 h in our level I...
Assessment of regional alveolar recruitment and derecruitment during protective respiratory therapy in lung failure is necessary to predict the process ventilatory avoid pulmonary complications. Different studies showed that clinical management ARDS can successfully be controlled by CT scan analysis [1]. Information about distribution ventilation also assessed bedside method electrical impedance tomography (EIT) [2]. To correlate assessment with EIT scans as a reference technique PEEP trial,...
Background: Micro-axial pumps are well-established temporary mechanical circulatory support devices (tMCS). Treatment strategies bridge-to-recovery or bridge-to-decision, as well high-risk elective cardiac surgeries. A new feature of the device is capability deriving left ventricular end-diastolic pressure from continuously measured LV-waveform. The objective was to evaluate precision this calculated LVEDP (cLVEDP) compared invasively pulmonary capillary wedge (PCWP) while using...