A5052602372- Sexual Differentiation and Disorders
- Hormonal and reproductive studies
- Bladder and Urothelial Cancer Treatments
- Sarcoma Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Growth Hormone and Insulin-like Growth Factors
- Peptidase Inhibition and Analysis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Breast Cancer Treatment Studies
- Inflammatory Biomarkers in Disease Prognosis
- HER2/EGFR in Cancer Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Diet and metabolism studies
- Uterine Myomas and Treatments
- Cancer Treatment and Pharmacology
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Corneal surgery and disorders
- Lung Cancer Research Studies
Memorial Ankara Hospital
2024-2025
Ankara Bilkent City Hospital
2023-2024
City Hospital
2024
Weatherford College
2024
Van Yüzüncü Yıl Üniversitesi
2014-2021
Despite the extensive research on hepatocellular carcinoma (HCC) exploring various treatment strategies, survival outcomes have remained unsatisfactory. The aim of this was to evaluate ability machine learning (ML) methods in predicting probability HCC patients. study retrospectively analyzed cases patients with stage 1-4 HCC. Demographic, clinical, pathological, and laboratory data served as input variables. researchers employed feature selection techniques identify key predictors patient...
Introduction: Biliary tract cancers (BTC) comprise a heterogeneous group of malignancies, including gallbladder cancer, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma. The main determinants prognosis in BTC are the stage disease eligibility for curative treatment. Additionally, liver functional capacity is also one factors influencing survival biliary cancers. age–bilirubin–INR–creatinine (ABIC) score has been previously shown to predict hepatic diseases. aim our study...
In this Turkish Oncology Group study, we aimed to evaluate the effectiveness of trastuzumab emtansine (TDM1) in adjuvant treatment early-stage human epidermal growth factor receptor-2 (HER2)-positive breast cancer with residual disease using real-life data. A total 13 centers participated study between September 2019 and October 2024. Patients HER2-positive who underwent surgery after completing neoadjuvant chemotherapy HER2-targeted therapies had invasive or axillary lymph nodes received...
Glycogenic hepatopathy is a rare cause of high transaminase levels in type 1 diabetes mellitus. This condition, characterized by elevated liver enzymes and hepatomegaly, caused irreversible excessive accumulation glycogen hepatocytes. case report on 19-year-old male case, diagnosed with glycogenic hepatopathy. After the diagnosis was documented biopsy, put glycemic control which led to significant decline hepatomegaly enzymes. It emphasized that, mellitus cases, should also be considered...
Introduction Letrozole is an aromatase inhibitor (AI), which suppresses plasma estrogen levels by inhibiting the enzyme, that causes conversion of androgens to in peripheral tissues. There very few information literature regarding development acute heart failure after AI use. We would like report a case patient who was started letrozole for hormonal treatment and developed due this. Case Fifty-seven-year-old woman with hormone positive breast cancer operated neoadjuvant chemotherapy received...
Menopause is a natural step in the process of aging. Postmenopausal women have decreased levels antioxidants and increased oxidative stress, latter which plays an important role atherogenesis. The aim present study was to evaluate relationship body mass index (BMI) with serum catalase activity, malondialdehyde (MDA), dehydroepiandrosterone sulfate (DHEAS) healthy postmenopausal estimate whether MDA/DHEAS ratio possible marker stress for determining cardiovascular risk these women.
Mild clinical signs of hyperandrogenism such as hirsutism may appear during the menopausal transition part normal aging process, but development frank virilization suggests a specific source androgen excess. We report case 68-year-old woman with that had started 6 months before. Clinical analyses revealed high levels serum testosterone for postmenopausal woman. Pelvic MRI and abdomen CT showed no evidence ovarian adrenal tumor. Postmenopausal can be result numerous etiologies ranging from...
ABS TRACT Objective: Synovial sarcoma, an aggressive subtype of soft tissue tumors, mainly occurs in young individuals.In patients with synovial the tumor is predominantly localized lower extremities, cases.The present study aimed to investigate contribution localization prognosis sarcoma and determine factors affecting patient survival.Material Methods: We retrospectively analyzed clinical data 35 who were treated at our clinic between February 2000 October 2022.Overall survival (OS)...
Colon lymphoma is a rare type of gastrointestinal and represents 0.2% to –1.2% all primary colon cancers. This study aimed retrospectively examine the general characteristics, treatment methods, survival characteristics patients with who were followed-up at our center. retrospective included diagnosed followed up Ankara Numune Training Research Hospital Bilkent City between December 2005 June 2023. Clinicopathological features, radiological findings, treatments, modalities obtained from...
Neuroendocrine tumors (NETs) originate from cells of the endocrine system.They are most commonly observed in gastrointestinal tract, lungs, bronchi, thymus, and pancreas.According to 2012 Surveillance, Epidemiology, End Results data, incidence NET was found be seven cases per 100,000 individuals. 1The has increased last three decades. colorectal NETs recent years is primarily attributed an increase use colonoscopies for cancer screening other indications.The estimated one case people. 2 In...
Epidermal growth factor receptor (EGFR) mutations like the common L858R and exon 19 deletions are well studied, but rarer insertions have received less attention. This case report describes a patient with this uncommon EGFR insertion mutation in metastatic lung adenocarcinoma. A 51-year-old male nonsmoker adenocarcinoma rare experienced disease progression on initial carboplatin-pemetrexed chemotherapy. However, treatment second-generation tyrosine kinase inhibitor afatinib led to partial...
Introduction: Endometrium cancer is the most common gynaecological malignancy in developed countries. In this study, we aimed to investigate effect of HER2 positivity on prognosis endometrial cancer. Methods: our patients admitted clinic with a diagnosis between September 2019 and December 2023 were retrospectively evaluated. Human epidermal growth factor receptor 2 (HER2) immunohistochemistry was performed 121 patients. HER2-low group (HER2 score: 0 1) HER2-high 3) defined according score...
Mean platelet volume (MPV) is associated with cardiovascular morbidity and mortality in type 2 diabetic patients. However, the effects of blood glucose regulation treatment regime on MPV has not been adequately studied Aims: We regimen mean Type patients.A total 232 patients who were admitted to hospital short intervals 3 months last years included study. When second admission HbA1c was greater than first HbA1c, they classified as being deteriorated group, otherwise improved group. Also,...
Abs tract Malignancy is an important cause of mortality in acromegaly. Hematological malignancies are very rare Here, we report 80-yearold patient with acromegaly and multiple myeloma. Patient died within a month diagnosis. Previous studies have shown that growth hormone somatomedin-C activate B lymphocyte receptors found myeloma cells. Possible effects on progression discussed the light relevant literature. Turk Jem 2013; 17: 75-8
Abstract Background Bladder cancer surgery is critical for treatment, and systemic treatment before or after cystectomy may be necessary. We aimed to investigate the efficacy response neoadjuvant adjuvant treatments. Methods Data on 93 patients with resectable muscle-invasive bladder were analyzed retrospectively. Patients who received chemotherapies included. The group was divided into pathological responders non-responders. Overall survival disease-free calculated. Results median age 61.5...