- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Proteins in Food Systems
- Receptor Mechanisms and Signaling
- Adenosine and Purinergic Signaling
- Neuroendocrine Tumor Research Advances
- Microencapsulation and Drying Processes
- Growth Hormone and Insulin-like Growth Factors
- Chemokine receptors and signaling
- Sarcoma Diagnosis and Treatment
- Renal and related cancers
- Multiple Myeloma Research and Treatments
- Inflammatory mediators and NSAID effects
- Categorization, perception, and language
- Plant-based Medicinal Research
- Psoriasis: Treatment and Pathogenesis
- Cancer Immunotherapy and Biomarkers
- Water Quality Monitoring Technologies
- Breast Cancer Treatment Studies
- Ubiquitin and proteasome pathways
- Breast Lesions and Carcinomas
- Circular RNAs in diseases
- Radiopharmaceutical Chemistry and Applications
- HER2/EGFR in Cancer Research
Tianjin Medical University Cancer Institute and Hospital
2024-2025
University of Wisconsin–Madison
2025
Kunming Medical University
2017-2020
Harrison International Peace Hospital
2018
Affiliated Hospital of Taishan Medical University
2010
Taishan Medical University
2007-2008
Objective: Tumor cell malignancy is indicated by histopathological differentiation and proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading classification in breast cancer neuroendocrine tumors. However, its prognostic significance pancreatic ductal adenocarcinoma (PDAC) remains uncertain. Methods: Patients who underwent radical pancreatectomy PDAC were retrospectively enrolled, relevant factors examined. Grade (GOM), a novel index based on proposed,...
Smoking is the leading cause of COPD. Exploring molecular markers and understanding pathogenic mechanisms smoking-related COPD are helpful for early clinical diagnosis treatment disease. This study aims to identify specific circulating microRNAs (miRNAs) from blood patients with a long history smoking.Blood samples four different groups were collected, miRNA microarray was performed. Differential expression miRNAs verified by quantitative polymerase chain reaction. In vitro, THP-1 cells...
Abstract Background Nuclear expression of CTNNB1 is occasionally negative in solid‐pseudopapillary neoplasm (SPN) the pancreas, leading to a missed diagnosis. In present study, we aimed investigate clinical significance mutation detection for diagnosing SPN and explore difference clinicopathological characteristics at different ages sex. Methods Patients who underwent surgery pathologically confirmed our institution between 2011 2020 were collected. Their data analyzed. Results The median...
Little progress has been made in recent years using first-line chemotherapy, including gemcitabine combined with nab-paclitaxel, FOLFIRINOX, and NALIRIFOX, for advanced pancreatic adenocarcinoma (APC). In addition, the optimal second-line chemotherapy regimen not determined. This study aimed to compare effectiveness of different types APC.
Insulin-like growth factor binding protein 2 (IGFBP2) is overexpressed in tumor tissues of several malignancies, including pancreatic cancer. Because its role progression, IGFBP2 has been investigated as a biomarker. However, little known about utility Plasma levels were determined using enzyme-linked immunosorbent assay 75 patients with ductal adenocarcinoma (PDAC), 73 matched healthy controls, and 17 chronic pancreatitis patients. Our results showed that the plasma IGFPB2 level was...
As a key component of inherent optical properties (IOPs) in ocean color remote sensing, phytoplankton absorption coefficient ($a_{phy}$), especially hyperspectral, greatly enhances our understanding community composition (PCC). The recent launches NASA's hyperspectral missions, such as EMIT and PACE, have created an urgent need for algorithms studying phytoplankton. Retrieving $a_{phy}$ from sensing coastal waters has been extremely challenging due to complex properties, causing traditional...
To explore the effects of thalidomide on ratio Th17 to Treg cells in peripheral blood and expression IL-17 IL-35 patients with multiple myeloma(MM), so as provide reference for clinical treatment MM.A total 82 MM treated from January 2014 December 2016 were enrolled group, 30 healthy subjects selected control (control group). The T cell subsets accounted CD4+T detected by flow cytometer. levels serum measured ELISA, differences various indexes compared between 2 groups.Compared significantly...