Shan Gao

ORCID: 0009-0001-6295-6505
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Crystal structures of chemical compounds
  • Metal-Organic Frameworks: Synthesis and Applications
  • Metal complexes synthesis and properties
  • Gas Sensing Nanomaterials and Sensors
  • Crystallography and molecular interactions
  • Analytical Chemistry and Sensors
  • Molecular Sensors and Ion Detection
  • Thermal properties of materials
  • Advanced Nanomaterials in Catalysis
  • Advanced Chemical Sensor Technologies
  • Electrochemical sensors and biosensors
  • Thyroid Disorders and Treatments
  • Synthesis and Characterization of Heterocyclic Compounds
  • Conducting polymers and applications
  • Covalent Organic Framework Applications
  • Magnetism in coordination complexes
  • Enzyme Catalysis and Immobilization
  • Advanced biosensing and bioanalysis techniques
  • Advanced Sensor and Energy Harvesting Materials
  • Nanoplatforms for cancer theranostics
  • Microbial Metabolic Engineering and Bioproduction
  • Structural and Chemical Analysis of Organic and Inorganic Compounds
  • Lanthanide and Transition Metal Complexes

First Affiliated Hospital of Xi'an Jiaotong University
2011-2025

Wuhan University
2025

Renmin Hospital of Wuhan University
2025

Wuhan Third Hospital
2025

Tongren Hospital
2025

Anhui Medical University
2007-2024

Shandong University of Technology
2024

Shenyang Center for Disease Control and Prevention
2024

China Medical University
2024

Liaoning Normal University
2024

With the advent of 5G era, hexagonal boron nitride (BN) platelets are ideal fillers to incorporate into polymers for preparing thermally conductive composites, which applied in relieving heat dissipation electronic devices. In this study, we report a green, low cost, and high-efficient method improve thermal conductivity (λ) carboxylated acrylonitrile-butadiene rubber (XNBR) composites via noncovalent modification tannic acid (TA) chemistry. The TA decorating on surface BN without...

10.1021/acs.iecr.1c02217 article EN Industrial & Engineering Chemistry Research 2021-08-23

Abstract Glucose and pH dual‐responsive insulin delivery carriers that have been validated in animal models, remain elusive much desired. Herein, a new class of covalent organic frameworks (COFs)‐based nanocarriers is developed by encapsulating (Ins) glucose oxidase (GOx) into COFs (COF‐1 COF‐5) via both Brønsted Lewis type (N:→B) complexations. Subsequently, polyethylene glycolated fluorescein isothiocyanate (FITC‐PEG) incorporated the exchange reactions between disulfide chains thiol...

10.1002/adhm.202000221 article EN Advanced Healthcare Materials 2020-06-16

Abstract Timely restoration of blood supply after myocardial ischemia is imperative for the treatment acute infarction but causes additional ischemia/reperfusion (MI/R) injury, which has not been hitherto effectively targeted by interventions MI/R injury. Hence, development advanced nanomedicine that can reduce apoptosis cardiomyocytes while protecting against in vivo utmost importance. Herein, a redox‐responsive and emissive TPE‐ss covalent organic framework (COF) nanocarrier integrating...

10.1002/smll.202205062 article EN Small 2022-10-17

With the rapid development of advanced microelectronic equipment, thermal interface materials with high conductivity and excellent mechanical properties have become an urgent need.

10.1039/d2tc00099g article EN Journal of Materials Chemistry C 2022-01-01

Inflammation plays an important role in the progression of cancer and other diseases, such as diabetes cardiovascular cerebrovascular diseases. The systemic immune-inflammation index (SII) was recognized objective biomarker reflecting immunoinflammatory status. This study aimed to identify association between SII with all-cause, non-cancer mortality among general population United States. 25,955 participants (≥ 20 years) were included from 2005 2018 National Health Nutrition Examination...

10.1186/s12889-025-21423-1 article EN cc-by-nc-nd BMC Public Health 2025-01-20

The hypermetabolic response associated with burns is characterized by skeletal muscle atrophy and an increased incidence of disability death. Significant remodeling the gut microbiota occurs after severe burn trauma. However, specific mechanisms which contribute to burn-induced remain unexplored. results showed that disruption exacerbated atrophy. Fecal metabolite analysis revealed perturbations, primarily within tryptophan (Trp) metabolic pathway. Animal models further demonstrated disorder...

10.1002/advs.202409296 article EN cc-by Advanced Science 2025-02-14

Abstract With the development of biotherapeutic field, biomacromolecules with definite curative and small side effects have gradually become a hot spot in research new drugs. However, use as drug candidates pose some technical difficulties related to their medicinal properties, mainly stability vivo transport delivery. Currently, diverse nanodrug delivery systems been used deliver because they can maintain stability, significantly increase bioavailability, improve targeted distribution...

10.1002/adtp.202200053 article EN Advanced Therapeutics 2022-07-15

There are scarce reports regarding the prognosis of a second course antithyroid drug (ATD) therapy on recurrent Graves' disease (GD). The aim this study was to assess long-term remission rate after ATD and verify significant clinical predictors remission.A prospective randomized trial with follow-up conducted evaluate effects therapy.A total 128 GD patients who had finished first regular were enrolled in study, prescribed methimazole (MMI) treatment titration regimen. randomly assigned two...

10.1530/eje-14-0704 article EN cc-by European Journal of Endocrinology 2014-12-03

Digital transformation shapes business operations across industries. The present study investigates the challenges of this in asset-intensive businesses. Based on a qualitative case metals and mining industry, explores early attempts to implement digital technology-enabled changes inter-organizational exchange as part firms' models their ecosystems. In particular, identifies related ways firms industry manage seize opportunities that technologies provide for operations. include lack...

10.24251/hicss.2019.593 article EN cc-by-nc-nd Proceedings of the ... Annual Hawaii International Conference on System Sciences/Proceedings of the Annual Hawaii International Conference on System Sciences 2019-01-01

Graves' disease is a common organ-specific autoimmune disease. The identity of its autoantigen, the TSH receptor (TSHR), was established and used to induce typical animal model. A-subunit, shed portion TSHR, either initiates or amplifies response thyroid gland, thereby causing in humans. In present study, we investigate effect TSHR A-subunit on induction murine neonatal tolerance for development Female BALB/c mice were pretreated with different doses adenovirus expressing (Ad-TSHR289) by ip...

10.1210/en.2010-0737 article EN Endocrinology 2011-02-02

Objective: Propofol is the most widely administered intravenous anesthetic to induce deep sedation for gastroscopy procedures. Coadministration of nalbuphine can provide analgesia and patients experiencing visceral pain, thereby decreasing amount propofol needed reducing risk propofol-induced adverse events. We carried out this study determine median effective dose (ED50) in combination with different dosages optimal dosage during painless gastroscopy. Methods: recruited sixty-five aged...

10.3389/fphar.2022.1014486 article EN cc-by Frontiers in Pharmacology 2022-09-20

A broadband and narrowband switchable terahertz (THz) absorber based on a bulk Dirac semimetal (BDS) strontium titanate (STO) is proposed. Narrowband absorption can be switched by adjusting the Fermi level of BDS. When BDS 100 meV, device an with three peaks. The frequencies are 0.44, 0.86, 1.96 THz, respectively, when temperature STO 250 K. By from to 500 K, blue shifts approximately 0.14, 0.32, 0.60 respectively. sensitivities peaks 0.56, 1.27, 2.38 GHz/K, adjusted 30 bandwidth 0.70 THz....

10.1364/ao.509826 article EN Applied Optics 2024-01-18

Glycyrrhetin urea has emerged as a privileged scaffold with anti-inflammatory activity for the treatment and prevention of acute kidney injury (AKI). In this study, structural modifications A ring glycyrrhetinic acid yielded series derivatives, among which compound 7o exhibited most promising activity. was confirmed to interact STING through cellular heat shift assay inhibit STING/NF-κB pathway in RAW264.7 cells. It acted on pathway, inhibited NF-κB phosphorylation, subsequently reduced...

10.1021/acsomega.4c09003 article EN cc-by-nc-nd ACS Omega 2024-11-28
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