- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Acute Ischemic Stroke Management
- Cerebral Venous Sinus Thrombosis
- Sleep and Wakefulness Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disorders and Treatments
- Neonatal Respiratory Health Research
- S100 Proteins and Annexins
- Trigeminal Neuralgia and Treatments
- Brain Metastases and Treatment
- Psychosomatic Disorders and Their Treatments
- Laser Applications in Dentistry and Medicine
- Sleep and related disorders
- Atrial Fibrillation Management and Outcomes
- Pediatric health and respiratory diseases
- Congenital Anomalies and Fetal Surgery
- Occupational and Professional Licensing Regulation
- Hedgehog Signaling Pathway Studies
University of Naples Federico II
2023
Università Cattolica del Sacro Cuore
1991-2014
Catholic University of America
2000-2013
Barrow Neurological Institute
1990
Neurological Surgery
1990
Cerebrospinal fluid shunting procedures are widely employed in the treatment of hydrocephalus and other disturbances dynamics cerebrospinal fluid. In spite its popularity, this operation frequently requires surgical revision. A retrospective analysis a series 356 adults who underwent insertion shunt between January 1970 December 1988 was performed. The incidence revision analyzed, an attempt made to identify possible causal factors. overall revisions 28.65%; number same patient ranged one...
We conducted a randomized, blinded controlled trial to test the efficacy of fibrinolytic therapy with tissue plasminogen activator and urokinase in treatment acute embolic stroke. Embolic stroke was simulated rabbits by injecting three 0.5 x mm fragments autologous arterial thrombus harvested from traumatized auricular artery. Thirty minutes after embolization were blindly treated (n = 21), 20), or 0.9% saline 20). At 6 hours sacrificed, cerebral vasculature inspected for location number...
Background and purpose Epileptic seizures account for 24–40% of all clinical onsets in patients with brain arteriovenous malformations ( AVM s). Methods We retrospectively reviewed the angioarchitectural features s associated 168 admitted to our Department from 1997 2012. Patients were dichotomized according demographic characteristics, type treatment, bleeding occurrence, morphological topographic features. Clinical status at admission discharge was also recorded. The association each one...
<h3>Background</h3> Single nucleotide polymorphisms (SNPs) on chromosome 9p21 have been recently associated with intracranial aneurysms and stroke. In this study, we tested the association between rs1333040C>T polymorphism locus sporadic brain arteriovenous malformations (BAVMs). <h3>Methods</h3> We studied 78 patients BAVMs 103 unaffected controls. Genomic DNA was isolated from peripheral blood assessed by PCR–restriction fragment length using BsmI restriction endonuclease....
Gait impairment is common in multiple sclerosis (MS), but difficult to evaluate clinical practice. In this proof-of-concept observational study, we compared walking ability recorded by Google Maps Timeline conventional measures people with MS.We used open-access record the total number of days activity, distance, time, and speed. Each variable was included a different stepwise linear regression model including all variables.We nine MS (age 43.1 ± 6.6 years; females 55.6%; disease duration...
A case of a girl with multiple spinal meningiomas, without evidence neurofibromatosis, is described. The patient first underwent the complete removal an intradural tumour at lower lumbar level, age eight year. second meningioma, located upper was surgically excised after five year symptom-free period.
A case of a thrombosed aneurysm the vein Galen in 9-year-old boy is reported. Previously, only ten clotted aneurysms have been described. In our case, thrombosis occurred spontaneously after birth. Clinical presentation was characterized by signs hydrocephalus, with an abrupt deterioration several years satisfactory clinical evolution. The patient successfully treated ventriculoperitoneal shunt.
We observed a 32-year-old female who had suffered from left hemisphere ischemic stroke with right hemiparesis at the age of seven. At that time, CT scan demonstrated lesion in nucleo-capsular region and cerebral angiogram documented complete occlusion supraclinoid segment internal carotid artery. When we patient neurological examination moderate brachio-crural hemiparesis. A brain MRI showed an old involving 'flow voids' suggestive for vascular malformation sylvian region. rotational 3-D...
408 Positional cerebral ischemia (PCI) is an extremely rare condition in which dramatic central nervous system deficits are triggered by standing patients with severe stenosis or occlusion of the major brain-supplying blood vessels [1] . Because PCI generally associated orthostatic hypotension [2, 3] , a hemodynamic mechanism has been proposed [4] However, reported even without The treatment medical, but surgery can be considered refractory cases (endarterectomy for carotid artery either...