Liyan Chen

ORCID: 0009-0001-9400-0241
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Research Areas
  • Phytoestrogen effects and research
  • Tea Polyphenols and Effects
  • Spine and Intervertebral Disc Pathology
  • Endometrial and Cervical Cancer Treatments
  • Protein Hydrolysis and Bioactive Peptides
  • Respiratory and Cough-Related Research
  • Probiotics and Fermented Foods
  • Food Quality and Safety Studies
  • Fermentation and Sensory Analysis
  • COVID-19 Clinical Research Studies
  • Medical Research and Treatments
  • Medical Imaging and Analysis
  • Hepatitis B Virus Studies
  • Lymphoma Diagnosis and Treatment
  • Cervical and Thoracic Myelopathy
  • Hepatitis C virus research
  • Asthma and respiratory diseases
  • Mycotoxins in Agriculture and Food
  • Regional Development and Environment
  • Dermatological and COVID-19 studies
  • Autoimmune Neurological Disorders and Treatments
  • Cancer-related molecular mechanisms research
  • Genetic and Environmental Crop Studies
  • Ginger and Zingiberaceae research
  • Migraine and Headache Studies

Institute of Chinese Materia Medica
2024

Nanjing Medical University
2024

Jiangsu Province Hospital
2024

First Affiliated Hospital of Jiangxi Medical College
2024

Jiangxi Provincial People's Hospital
2024

Chinese Academy of Agricultural Sciences
2014-2023

Tea Research Institute
2014-2023

Weihai Maternal and Child Health Hospital
2023

Fujian Medical University
2023

Union Hospital
2023

Background Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a promising brain modality in poststroke upper extremity rehabilitation. Although several studies have examined the safety and reliability of taVNS, mechanisms underlying motor recovery stroke patients remain unclear. Objectives This study aimed to investigate effects taVNS paired with task-oriented training (TOT) on function subacute explore potential mechanisms. Methods In this double-blinded, randomized,...

10.3389/fnins.2024.1346634 article EN cc-by Frontiers in Neuroscience 2024-03-08

Objective: To explore the effects of mindfulness-based stress reduction (MBSR) training combined with dexmedetomidine hydrochloride preemptive sedation on postoperative sleep quality in patients undergoing laparoscopic ovarian tumor resection. By comparing quality, pain scores, anxiety and adverse reactions among three groups patients, clinical efficacy this treatment was evaluated. Methods: A total 123 resection hospital from January 2022 to December 2023 were included. Based interventions,...

10.26689/jcnr.v8i12.9051 article EN Journal of Clinical and Nursing Research 2025-01-02

ABSTRACT Antinutritional factors in soy meal (SM) include trypsin inhibitor, galactooligosaccharides (GOSs), structural polysaccharides, and large‐molecular‐weight protein. These antinutritional limit the usage of SM for young monogastric animals. Aspergillus oryzae solid‐state fermentation was applied to eliminate these factors, changes physical chemical characteristics were investigated. A. –treated more nutrient dependent than oxygen dependent, which illustrated by scanning electron...

10.1094/cchem-01-13-0007-r article EN Cereal Chemistry 2013-06-12

BACKGROUND:Since the outbreak of COVID-19 in December 2019, there have been 96 623 laboratory-confirmed cases and 4784 deaths by 29 China. We aimed to analyze risk factors incidence thrombosis from patients with confirmed pneumonia. MATERIAL AND METHODS:Eighty-eight inpatients pneumonia were reported (31 critical cases, 33 severe 24 common cases). The factor assessment, laboratory results, ultrasonographic findings, prognoses these analyzed, compared among groups different severity....

10.12659/msm.929708 article EN Medical Science Monitor 2021-02-10

Detection for cough in mice has never yielded clearly audible sounds, so there is still a great deal of debates as to whether can response tussive stimuli. Here we introduce an approach detection mouse based on sound monitoring and airflow signals. 40 Female BALB/c were pretreated with normal saline, codeine, capasazepine or desensitized capsaicin. Single was put plethysmograph, exposed aerosolized 100 µmol/L capsaicin 3 min, followed by continuous observation min. Airflow signals total 6...

10.1371/journal.pone.0059263 article EN cc-by PLoS ONE 2013-03-21

A method based on ultrasonic extraction (USE) followed by LC-MS is presented for the determination of vitexin and isovitexin in pigeonpea extracts this study. The influential parameters USE procedure were optimized, optimal conditions as follows: solvent, 60% ethanol solution; liquid/solid ratio 10:1 (mL/g), power, 250 W; temperature, 40-50 degrees C; three cycles, each cycle 15 min. Validation was performed terms repeatability reproducibility. RSDs yields lower than 5.85 8.09%,...

10.1002/jssc.200700312 article EN Journal of Separation Science 2008-01-14

Abstract Objective This study aims to investigate blood and biochemical laboratory findings in patients with coronavirus disease (COVID‐19) analyze the potential predictors of poor outcome COVID‐19. Methods The clinical, laboratory, data 87 COVID‐19 were collected retrospectively analyzed. Only at time admission used analysis for outcome. These divided into two groups: adverse prognosis group (36 patients) non‐adverse (51 patients). was defined as intensive care unit or death. Results On...

10.1002/jcla.23598 article EN cc-by-nc-nd Journal of Clinical Laboratory Analysis 2020-09-28

Ordered mesoporous silica SBA-15 with different pore size and organic groups (–SH, –NH2, –COOH) were synthesized. The adsorption of (−)-epigallocatechin gallate (EGCG) from green tea extract (GTE) was conducted on these functional ordered SBA-15, which studied as a class potential adsorbents. performance EGCG correlated the surface chemistry size. Amino-functionalized (SBA-15-NH2) large (10.7 nm) exhibited extremely rapid rate well high capacity 287 mg g−1 for adsorbing at 25 °C, is much...

10.1039/c4ra06922f article EN RSC Advances 2014-07-30

Abstract BACKGROUND Ginseng‐Douchi (GD) is a complex fermented product of ginseng and soybean, similar to natto, effective in the treatment hyperlipidemia, but mechanism action involved needs be further explored. RESULTS The present study combines comprehensive strategy network pharmacology metabolomics explore lipid‐lowering GD. First, hyperlipidemia rats model induced by high‐fat diet was established evaluate therapeutic effects Second, potential biomarkers were identified using serum...

10.1002/jsfa.13858 article EN Journal of the Science of Food and Agriculture 2024-09-12

Abstract Rationale: Endometrial neuroendocrine carcinoma is a rare histological subtype of endometrial cancer, divided into low-grade (carcinoid) and high-grade (small cell large carcinoma). It characterized by high invasiveness poor prognosis. L/SCNEC an extremely pathological type carcinoma, the number reports on this condition few globally. Patient concerns: A 54-year-old Chinese female presented with vaginal bleeding. Diagnoses: Outpatient hysteroscopy biopsy were performed, examination...

10.1097/md.0000000000016433 article EN cc-by-nc Medicine 2019-07-01

Purpose Idiopathic sudden sensorineural hearing loss is a clinical emergency with an increased incidence of occurrence in recent years. Hyperbaric oxygen has been widely used the treatment loss. However, prognostic factors related to its curative effects are still not clear, which hinders application. The aim this study was investigate efficacy and hyperbaric therapy (HBOT) plus drug therapies Method Patients who were treated from April October 2017 retrospectively included. Clinical...

10.1044/2018_aja-18-0095 article EN American Journal of Audiology 2019-02-28

Thymoma is an uncommon neoplasia derived from the epithelial cells of thymus, which leads to immune dysregulation and associated with a series autoimmune diseases. However, concurrence these disease entities rare, exact mechanisms diseases are still unclear. We have admitted several cases who were diagnosed thymoma, haemolytic anaemia, pure red cell aplasia. These first report three disorders. After thymectomy, anaemia improved, decreased, haemoglobin was normalized.

10.1159/000503376 article EN Acta Haematologica 2020-01-01

Abstract Eosinophilic bronchitis (EB) is a clinical disease characterized by chronic cough, airway eosinophil infiltration, and responsive to steroid therapy but with the absence of hyperreactivity (AHR). This study established an EB mouse model all above features. First, 42 mice were divided into 7 groups investigate optimal time interval between cough AHR detections. Afterward, 28 asthma, EB, normal saline (NS), dexamethasone (DXM) groups. Mice challenged using nasal drops 200 µg ovalbumin...

10.1038/s41598-020-67475-8 article EN cc-by Scientific Reports 2020-06-29

The roles of microRNA (miRNA/miR)‑383‑5p have been reported in several malignancies, including breast cancer, gastric ovarian cancer and lung adenocarcinoma. However, its function diffuse large B‑cell lymphoma (DLBCL) remains unclear. Thus, the present study aimed to investigate role miR‑383‑5p DLCBL. Reverse transcription‑quantitative PCR analysis was performed detect expression 80 paired tissue samples from patients with DLBCL control subjects, as well related cell lines. Kaplan‑Meier...

10.3892/ol.2021.12776 article EN Oncology Letters 2021-05-06

As one of the important elements excellent traditional Chinese culture, “carrying things with kindness, promoting virtue and spreading morality” has gone through thousands years vicissitudes life cohesion core essence moral concepts nation. The spiritual pursuit lies in emphasis on profound a tolerant mindset, carrying all tolerating differences one’s own cultivation behaviour, actively forward light morality, thereby social harmony development. is highly compatible socialist values new era,...

10.22158/sssr.v5n4p223 article EN Studies in Social Science Research 2024-12-19

Patients with bicuspid stenosis often have anatomical characteristics such as elliptical valve rings, high and asymmetric calcification, unequal leaflets, concomitant widening of the ascending aorta and/or transverse heart. These unfavorable factors are more likely to cause poor placement transcatheter aortic replacement (TAVR) valves, expansion stents, which can lead reduced durability, residual perivalve leakage, rupture rings surrounding structures, serious surgical related complications...

10.59958/hsf.7005 article EN The Heart Surgery Forum 2024-04-21

The purpose of this prospective case-control study was to evaluate the clinical effects and host immune response in patients with chronic hepatitis B (CHB) treated either entecavir (ETV)or adefovir dipivoxil (ADV).Forty-two diagnosed CHB were recruited randomly assigned receive ADV (n=19) or ETV(n=18) followed for a minimum 96 weeks.Serum virus (HBV) DNA, e antigen antibody (HBeAg, HBeAb), alanine amino-transferase (ALT) aspartate aminotransferase(AST) measured at baseline every 24 weeks...

10.5754/hge12287 article EN Hepatogastroenterology 2012-05-22
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