Rekha Ramachandran

ORCID: 0009-0002-0184-0426
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About
Contact & Profiles
Research Areas
  • Shoulder Injury and Treatment
  • Orthopedic Surgery and Rehabilitation
  • Foot and Ankle Surgery
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health disparities and outcomes
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Smoking Behavior and Cessation
  • Musculoskeletal Disorders and Rehabilitation
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Air Quality and Health Impacts
  • COVID-19 and Mental Health
  • Lung Cancer Treatments and Mutations
  • Gallbladder and Bile Duct Disorders
  • Pneumothorax, Barotrauma, Emphysema
  • Pancreatic and Hepatic Oncology Research
  • Lung Cancer Diagnosis and Treatment
  • Total Knee Arthroplasty Outcomes
  • Global Cancer Incidence and Screening
  • Shoulder and Clavicle Injuries
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Behavioral Health and Interventions
  • Acute Ischemic Stroke Management
  • Elbow and Forearm Trauma Treatment
  • Liver Disease Diagnosis and Treatment
  • Management of metastatic bone disease

University of Alabama at Birmingham
2014-2024

Deggendorf Institute of Technology
2024

Mayo Clinic
2015

University of Alabama
2014-2015

Harvard University
2014

University of Cincinnati
2014

Brigham and Women's Hospital
2014

Clinical Research Institute
2014

Duke University
2014

Mayo Clinic in Florida
2014

Background— The accuracy of stroke diagnosis in administrative claims for a contemporary population Medicare enrollees has not been studied. We assessed the validity diagnostic coding algorithms identifying by linking data from REasons Geographic And Racial Differences Stroke (REGARDS) Study to claims. Methods and Results— REGARDS enrolled 30 239 participants ≥45 years United States between 2003 2007. experts adjudicated suspected strokes, using retrieved medical records. linked...

10.1161/circoutcomes.113.000743 article EN Circulation Cardiovascular Quality and Outcomes 2014-06-25

We assessed the age-related differences in use of total shoulder arthroplasty (TSA) and outcomes, associated time-trends using United States Nationwide Inpatient Sample (NIS) between 1998 2010. Age was categorised as < 50, 50 to 64, 65 79 ≥ 80 years. Time-trends TSA were compared logistic regression or Cochran Armitage test. The overall increased from 2.96/100 000 12.68/100 Significantly lower rates noted 2009 2010, with 2000, for: mortality, 0.1% versus 0.2% (p = 0.004); discharge an...

10.1302/0301-620x.97b10.35696 article EN The Bone & Joint Journal 2015-10-01

To assess the association of hospital procedure volume for total shoulder arthroplasty (TSA) with patient outcomes and complications.We used US Nationwide Inpatient Sample from 1998-2011 to study annual TSA characteristics outcomes, including discharge disposition (home versus inpatient facility), length index hospitalization, postarthroplasty periprosthetic fracture, revision. Annual was categorized as <5, 5-9, 10-14, 15-24, ≥25 procedures annually.Patients receiving at higher hospitals...

10.1002/acr.22507 article EN Arthritis Care & Research 2014-11-04

Tumor cells are known to undergo considerable metabolic reprogramming meet their unique demands and drive tumor growth. At the same time, this may come at a cost with resultant vulnerabilities. The small molecule L-2-hdroxyglutarate (L-2HG) is elevated in most common histology of renal cancer. Similar other oncometabolites, L-2HG has potential profoundly impact gene expression. Here, we demonstrate that remodels amino acid metabolism cancer through combined effects on histone methylation RNA...

10.1172/jci171294 article EN cc-by Journal of Clinical Investigation 2024-05-14

Chronic obstructive pulmonary disease (COPD) is associated with a two-to-five fold increase in the risk of coronary artery independent shared factors. This association hypothesized to be mediated by systemic inflammation but this link has not been established. We included 300 participants enrolled SPIROMICS cohort, 75 each lifetime non-smokers, smokers without airflow obstruction, mild-moderate COPD, and severe-very severe COPD. quantified emphysema airway on computed tomography,...

10.1186/s12931-018-0946-1 article EN cc-by Respiratory Research 2018-12-01

Information about survival outcomes in metastatic biliary tract cancer (BTC) is sparse, and the numbers often quoted are based on reports of clinical trials data that may not be representative patients treated real world. Furthermore, impact more widespread adoption a standardized combination chemotherapy regimen since 2010 unclear.

10.1177/10732748231211764 article EN cc-by-nc Cancer Control 2023-01-01

Inequities in pollution-attributable health disparities are similar most urban areas throughout the United States, and appear to encompass racial socio-demographic differences, thereby suggesting increased risks for those living these areas. Individuals residing close proximity Superfund sites, predominantly people of color, increasingly stricken with lung diseases. The prevalence chronic diseases, such as obstructive pulmonary disease (COPD), asthma children, lower respiratory tract...

10.3390/ijerph19159271 article EN International Journal of Environmental Research and Public Health 2022-07-28

The prevalence of nonalcoholic fatty liver disease is rapidly rising. We aimed to investigate associations diet quality and dietary patterns with (NAFLD) in Black White adults. included 1726 participants who attended the Year 20 Exam Coronary Artery Risk Development Young Adults (CARDIA) study had their attenuation (LA) measured using computed tomography at 25 (2010-2011). NAFLD was defined as an LA ≤51 Hounsfield units after exclusion other causes fat. a priori diet-quality score (APDQS)...

10.3390/nu14040854 article EN Nutrients 2022-02-18

Abstract Background Given the dearth of data regarding time to treatment initiation (TTI) in palliative setting, and its impact on survival outcomes, we sought determine TTI a real‐world cohort metastatic colorectal cancer (mCRC) pancreatic (mPC) patients evaluate outcomes. Methods We collected for mCRC mPC from Flatiron Health electronic health records (EHR) derived database. divided into 3 categories: &lt; 2 weeks, 2–&lt; 4 4–8 diagnosis first‐line therapy. Outcome measures were median...

10.1002/cam4.5133 article EN cc-by Cancer Medicine 2022-08-17

Abstract Introduction Smoking is a key determinant of mortality among people living with HIV (PLWH). Methods To better understand the effects smoking cessation interventions in PLWH, we conducted pooled analysis four randomized controlled trials hospital-initiated through Consortium Hospitals Advancing Research on Tobacco (CHART). In each study, cigarette smokers were randomly assigned to usual care or intervention. The primary outcome was self-reported past 30-day tobacco abstinence at...

10.1093/ntr/ntz168 article EN Nicotine & Tobacco Research 2019-09-13

Expectancies demonstrate cross-sectional associations with e-cigarette use, but the prospective relationships between expectancies and use are unknown. This study examined longitudinal of among hospitalized tobacco cigarette smokers. E-cigarette (e-cigarette-specific Brief Smoking Consequences Questionnaire-Adult [BSCQ-A]), (tobacco-specific BSCQ-A), number days used e-cigarettes in past 30 were assessed at baseline hospitalization, 6-months post-hospitalization, 12-months...

10.1093/ntr/ntx043 article EN Nicotine & Tobacco Research 2017-02-11

ABSTRACT Purpose Low-dose computed tomography lung cancer screening is effective for reducing mortality. It critical to understand the practices screen-eligible individuals living in Alabama and Georgia where leading cause of death. High incidence mortality rates are attributed high smoking among underserved, low income, rural populations. Therefore, purpose this study: (1) define sociodemographic clinical characteristics patients who were screened at an Academic Medical Center (AMC) a...

10.1101/2024.05.12.24307248 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-05-13

Background: Pregnancy in adolescents continues to remain a significant public health challenge, with repeat pregnancies this age group often receiving insufficient attention. In Uganda, adolescent pregnancy varies between 26.1% and 55.6%. Evidence shows that adolescence is more common settings of high poverty, low educational attainment use long-acting reversible contraceptives among others. Objectives: The main aim study determine the underlying risk protective factors Uganda. Design: This...

10.1177/17455057241302449 article EN cc-by-nc Women s Health 2024-01-01
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