- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Biomarkers in Disease Mechanisms
- Neurological Disease Mechanisms and Treatments
- Immune Response and Inflammation
- Air Quality and Health Impacts
- Bone fractures and treatments
- Elbow and Forearm Trauma Treatment
- Fetal and Pediatric Neurological Disorders
- Prenatal Screening and Diagnostics
- Facial Nerve Paralysis Treatment and Research
- Autoimmune and Inflammatory Disorders Research
- Parvovirus B19 Infection Studies
- Neurogenesis and neuroplasticity mechanisms
- Systemic Lupus Erythematosus Research
- Inflammasome and immune disorders
- Multiple Sclerosis Research Studies
- Gut microbiota and health
- interferon and immune responses
- Ophthalmology and Eye Disorders
- Head and Neck Surgical Oncology
- Barrier Structure and Function Studies
- Trigeminal Neuralgia and Treatments
- Smoking Behavior and Cessation
Weifang Medical University
2024
University of South China
2024
First Hospital of Jilin University
2018
Jilin University
2018
First Bethune Hospital of Jilin University
2012
Abstract Background and purpose This study aims to examine the global, regional, national burden of ischemic stroke from 1990 2021. Method We used data Global Burden Disease (GBD) 2021 database comprehensively assess indicators globally, regionally, in 204 countries, including incidence, deaths, disability‐adjusted life years (DALYs), estimated annual percentage change (EAPC), Joinpoint regression analysis. Results In 2021, there were a total 7,804,449 cases globally (95% uncertainty...
Ischemic stroke, a major contributor to global disability and mortality, is underpinned by intricate pathophysiological mechanisms, notably neuroinflammation immune cell dynamics. Prior research has identified nuanced often paradoxical link between phenotypes ischemic stroke susceptibility. The aim of this study was elucidate the potential causal links median fluorescence intensity (MFI) morphological parameters (MP) 731 types risk.
1. Nomani AZ, Nabi S, Badshah M, Ahmed S. Review of acute ischaemic stroke in Pakistan: progress management and future perspectives. Stroke Vasc Neurol. 2017;2(1):30-39. doi:10.1136/svn-2016-000041 CrossRef Google Scholar
Rheumatoid arthritis (RA) is a global epidemic. We conducted cross-sectional study using the Global Burden of Disease (GBD) 2021 dataset to examine RA trends in patients aged 20-54 years worldwide. Key outcomes included incidence, mortality, and disability-adjusted life (DALYs), as well over time, stratifying by region, country, age, sex, Sociodemographic Index (SDI). also assessed contribution smoking RA-related mortality DALYs. Over past 32 years, incidence rate increased from 11.66 (95%...
Introduction: Childhood epilepsy is a major global health challenge with severe outcomes such as depression, intellectual disability, and increased suicide risk. It vital to understand epidemiological trends risk factors effectively address the condition's burden. Methods: This cross-sectional study utilized data from Global Burden of Disease (GBD) study, covering 204 countries 1990 2021, focusing on children aged 0 14 years epilepsy. We analyzed in incidence, mortality, disability-adjusted...
Stroke, a debilitating cerebrovascular ailment, poses significant threats to human life and health. The intricate interplay between the gut‑brain‑microbiota axis (GBMA) cerebral ischemia‑reperfusion has increasingly become focal point of scientific exploration, emerging as pivotal research avenue in stroke pathophysiology. In present review, authors delved into nexus GBMA neuroinflammation observed post‑stroke. analysis underscored roles histone deacetylase 3 neutrophil extracellular traps...
Background: Blood-brain barrier (BBB) pathology exists in neuromyelitis optica spectrum disorders (NMOSD). However, the clinical use of BBB permeability, such as predicting disease severity NMOSD, has rarely been studied a large cohort patients. Objectives: The current study explored association between permeability and parameters order to assess if could be biomarker predict characteristics NMOSD. Methods: Among 69 enrolled NMOSD patients, 47 with albumin index over 5 × 10-3 were assigned...
The cGAS–STING pathway plays an important role in ischemia-reperfusion injury the heart, liver, brain, and kidney, but its mechanisms cerebral have not been systematically reviewed. Here, we outline components of then analyze autophagy, ferroptosis, cellular pyroptosis, disequilibrium calcium homeostasis, inflammatory responses, disruption blood–brain barrier, microglia transformation, complement system activation following injury. We further value inhibitors treatment conclude that can...
The study aimed to provide the anatomic data for puncture of foramen ovale cranium in oral cavity. We scan 100 volunteers' skull on computed tomography who have no lesion base, which images were three-dimensional reconstruction. following observations and measurements carried out: shape, size cranium, angle length line. results we got are following: appears as oval, kidney round, pear strip shape. Foramen diameter is 8.20 ± 1.54 mm, width 4.08 0.73 mm men 4.23 0.79 female. distance from...
Ischemic stroke is a major global health issue, with active smoking identified as key modifiable risk factor. This study examines the burden of ischemic due to from 1990 2021, across different sociodemographic contexts.